Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions
Interspecific hybridization is a route for transgenes from genetically modified (GM) animals to invade wild populations, yet the ecological effects and potential risks that may emerge from such hybridization are unknown. Through experimental crosses, we demonstrate transmission of a growth hormone t...
Published in: | Proceedings of the Royal Society B: Biological Sciences |
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crroyalsociety:10.1098/rspb.2013.1047 2024-06-23T07:51:19+00:00 Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions Oke, Krista B. Westley, Peter A. H. Moreau, Darek T. R. Fleming, Ian A. 2013 http://dx.doi.org/10.1098/rspb.2013.1047 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2013.1047 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2013.1047 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Proceedings of the Royal Society B: Biological Sciences volume 280, issue 1763, page 20131047 ISSN 0962-8452 1471-2954 journal-article 2013 crroyalsociety https://doi.org/10.1098/rspb.2013.1047 2024-06-10T04:15:16Z Interspecific hybridization is a route for transgenes from genetically modified (GM) animals to invade wild populations, yet the ecological effects and potential risks that may emerge from such hybridization are unknown. Through experimental crosses, we demonstrate transmission of a growth hormone transgene via hybridization between a candidate for commercial aquaculture production, GM Atlantic salmon ( Salmo salar ) and closely related wild brown trout ( Salmo trutta ). Transgenic hybrids were viable and grew more rapidly than transgenic salmon and other non-transgenic crosses in hatchery-like conditions. In stream mesocosms designed to more closely emulate natural conditions, transgenic hybrids appeared to express competitive dominance and suppressed the growth of transgenic and non-transgenic (wild-type) salmon by 82 and 54 per cent, respectively. To the best of our knowledge, this is the first demonstration of environmental impacts of hybridization between a GM animal and a closely related species. These results provide empirical evidence of the first steps towards introgression of foreign transgenes into the genomes of new species and contribute to the growing evidence that transgenic animals have complex and context-specific interactions with wild populations. We suggest that interspecific hybridization be explicitly considered when assessing the environmental consequences should transgenic animals escape to nature. Article in Journal/Newspaper Atlantic salmon Salmo salar The Royal Society Proceedings of the Royal Society B: Biological Sciences 280 1763 20131047 |
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The Royal Society |
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crroyalsociety |
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English |
description |
Interspecific hybridization is a route for transgenes from genetically modified (GM) animals to invade wild populations, yet the ecological effects and potential risks that may emerge from such hybridization are unknown. Through experimental crosses, we demonstrate transmission of a growth hormone transgene via hybridization between a candidate for commercial aquaculture production, GM Atlantic salmon ( Salmo salar ) and closely related wild brown trout ( Salmo trutta ). Transgenic hybrids were viable and grew more rapidly than transgenic salmon and other non-transgenic crosses in hatchery-like conditions. In stream mesocosms designed to more closely emulate natural conditions, transgenic hybrids appeared to express competitive dominance and suppressed the growth of transgenic and non-transgenic (wild-type) salmon by 82 and 54 per cent, respectively. To the best of our knowledge, this is the first demonstration of environmental impacts of hybridization between a GM animal and a closely related species. These results provide empirical evidence of the first steps towards introgression of foreign transgenes into the genomes of new species and contribute to the growing evidence that transgenic animals have complex and context-specific interactions with wild populations. We suggest that interspecific hybridization be explicitly considered when assessing the environmental consequences should transgenic animals escape to nature. |
format |
Article in Journal/Newspaper |
author |
Oke, Krista B. Westley, Peter A. H. Moreau, Darek T. R. Fleming, Ian A. |
spellingShingle |
Oke, Krista B. Westley, Peter A. H. Moreau, Darek T. R. Fleming, Ian A. Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions |
author_facet |
Oke, Krista B. Westley, Peter A. H. Moreau, Darek T. R. Fleming, Ian A. |
author_sort |
Oke, Krista B. |
title |
Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions |
title_short |
Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions |
title_full |
Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions |
title_fullStr |
Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions |
title_full_unstemmed |
Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions |
title_sort |
hybridization between genetically modified atlantic salmon and wild brown trout reveals novel ecological interactions |
publisher |
The Royal Society |
publishDate |
2013 |
url |
http://dx.doi.org/10.1098/rspb.2013.1047 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2013.1047 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2013.1047 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Proceedings of the Royal Society B: Biological Sciences volume 280, issue 1763, page 20131047 ISSN 0962-8452 1471-2954 |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rspb.2013.1047 |
container_title |
Proceedings of the Royal Society B: Biological Sciences |
container_volume |
280 |
container_issue |
1763 |
container_start_page |
20131047 |
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1802642367032852480 |