Genetic rescue and inbreeding depression in Mexican wolves
Although inbreeding can reduce individual fitness and contribute to population extinction, gene flow between inbred but unrelated populations may overcome these effects. Among extant Mexican wolves ( Canis lupus baileyi ), inbreeding had reduced genetic diversity and potentially lowered fitness, and...
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crroyalsociety:10.1098/rspb.2007.0785 2024-09-15T18:01:16+00:00 Genetic rescue and inbreeding depression in Mexican wolves Fredrickson, Richard J Siminski, Peter Woolf, Melissa Hedrick, Philip W 2007 http://dx.doi.org/10.1098/rspb.2007.0785 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2007.0785 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2007.0785 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Proceedings of the Royal Society B: Biological Sciences volume 274, issue 1623, page 2365-2371 ISSN 0962-8452 1471-2954 journal-article 2007 crroyalsociety https://doi.org/10.1098/rspb.2007.0785 2024-08-19T04:24:56Z Although inbreeding can reduce individual fitness and contribute to population extinction, gene flow between inbred but unrelated populations may overcome these effects. Among extant Mexican wolves ( Canis lupus baileyi ), inbreeding had reduced genetic diversity and potentially lowered fitness, and as a result, three unrelated captive wolf lineages were merged beginning in 1995. We examined the effect of inbreeding and the merging of the founding lineages on three fitness traits in the captive population and on litter size in the reintroduced population. We found little evidence of inbreeding depression among captive wolves of the founding lineages, but large fitness increases, genetic rescue, for all traits examined among F 1 offspring of the founding lineages. In addition, we observed strong inbreeding depression among wolves descended from F 1 wolves. These results suggest a high load of deleterious alleles in the McBride lineage, the largest of the founding lineages. In the wild, reintroduced population, there were large fitness differences between McBride wolves and wolves with ancestry from two or more lineages, again indicating a genetic rescue. The low litter and pack sizes observed in the wild population are consistent with this genetic load, but it appears that there is still potential to establish vigorous wild populations. Article in Journal/Newspaper Canis lupus The Royal Society Proceedings of the Royal Society B: Biological Sciences 274 1623 2365 2371 |
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Open Polar |
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The Royal Society |
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crroyalsociety |
language |
English |
description |
Although inbreeding can reduce individual fitness and contribute to population extinction, gene flow between inbred but unrelated populations may overcome these effects. Among extant Mexican wolves ( Canis lupus baileyi ), inbreeding had reduced genetic diversity and potentially lowered fitness, and as a result, three unrelated captive wolf lineages were merged beginning in 1995. We examined the effect of inbreeding and the merging of the founding lineages on three fitness traits in the captive population and on litter size in the reintroduced population. We found little evidence of inbreeding depression among captive wolves of the founding lineages, but large fitness increases, genetic rescue, for all traits examined among F 1 offspring of the founding lineages. In addition, we observed strong inbreeding depression among wolves descended from F 1 wolves. These results suggest a high load of deleterious alleles in the McBride lineage, the largest of the founding lineages. In the wild, reintroduced population, there were large fitness differences between McBride wolves and wolves with ancestry from two or more lineages, again indicating a genetic rescue. The low litter and pack sizes observed in the wild population are consistent with this genetic load, but it appears that there is still potential to establish vigorous wild populations. |
format |
Article in Journal/Newspaper |
author |
Fredrickson, Richard J Siminski, Peter Woolf, Melissa Hedrick, Philip W |
spellingShingle |
Fredrickson, Richard J Siminski, Peter Woolf, Melissa Hedrick, Philip W Genetic rescue and inbreeding depression in Mexican wolves |
author_facet |
Fredrickson, Richard J Siminski, Peter Woolf, Melissa Hedrick, Philip W |
author_sort |
Fredrickson, Richard J |
title |
Genetic rescue and inbreeding depression in Mexican wolves |
title_short |
Genetic rescue and inbreeding depression in Mexican wolves |
title_full |
Genetic rescue and inbreeding depression in Mexican wolves |
title_fullStr |
Genetic rescue and inbreeding depression in Mexican wolves |
title_full_unstemmed |
Genetic rescue and inbreeding depression in Mexican wolves |
title_sort |
genetic rescue and inbreeding depression in mexican wolves |
publisher |
The Royal Society |
publishDate |
2007 |
url |
http://dx.doi.org/10.1098/rspb.2007.0785 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2007.0785 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2007.0785 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_source |
Proceedings of the Royal Society B: Biological Sciences volume 274, issue 1623, page 2365-2371 ISSN 0962-8452 1471-2954 |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rspb.2007.0785 |
container_title |
Proceedings of the Royal Society B: Biological Sciences |
container_volume |
274 |
container_issue |
1623 |
container_start_page |
2365 |
op_container_end_page |
2371 |
_version_ |
1810438440856059904 |