Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents
In the previous communication experiments were described which had been made with the Urease present in the Soja bean proving that the enzyme is strictly selective in its action and that whilst its activity is much reduced by ammonia it is increased, in a remarkable manner, by the presence of carbon...
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crroyalsociety:10.1098/rspb.1913.0029 2024-06-02T08:05:12+00:00 Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents 1913 http://dx.doi.org/10.1098/rspb.1913.0029 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.1913.0029 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character volume 86, issue 588, page 328-343 ISSN 0950-1193 2053-9185 journal-article 1913 crroyalsociety https://doi.org/10.1098/rspb.1913.0029 2024-05-07T14:16:29Z In the previous communication experiments were described which had been made with the Urease present in the Soja bean proving that the enzyme is strictly selective in its action and that whilst its activity is much reduced by ammonia it is increased, in a remarkable manner, by the presence of carbonic acid: in other words, the two products of change affect the activity of the enzyme in opposite ways—a result altogether without precedent. In explanation of these results, the suggestion was made that Urease is a feebly acidic substance. Though it was obvious that the results were not to be harmonised with the views that were current as to the manner in which enzymes act, we refrained from comment, deeming it desirable to obtain more information before discussing the new situation that was created. In the interval, the behaviour of other enzymes has been under observation by Dr. E. F. Armstrong and ourselves and it is proposed to discuss the general outcome of the work, in a comprehensive communication, at an early date. Meanwhile, we desire to bring forward an account of further observations on Urease carried out with the object of ascertaining the manner in which the activity of the enzyme is affected by the presence of various substances together with the urea. Article in Journal/Newspaper Carbonic acid The Royal Society Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character 86 588 328 343 |
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In the previous communication experiments were described which had been made with the Urease present in the Soja bean proving that the enzyme is strictly selective in its action and that whilst its activity is much reduced by ammonia it is increased, in a remarkable manner, by the presence of carbonic acid: in other words, the two products of change affect the activity of the enzyme in opposite ways—a result altogether without precedent. In explanation of these results, the suggestion was made that Urease is a feebly acidic substance. Though it was obvious that the results were not to be harmonised with the views that were current as to the manner in which enzymes act, we refrained from comment, deeming it desirable to obtain more information before discussing the new situation that was created. In the interval, the behaviour of other enzymes has been under observation by Dr. E. F. Armstrong and ourselves and it is proposed to discuss the general outcome of the work, in a comprehensive communication, at an early date. Meanwhile, we desire to bring forward an account of further observations on Urease carried out with the object of ascertaining the manner in which the activity of the enzyme is affected by the presence of various substances together with the urea. |
format |
Article in Journal/Newspaper |
title |
Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents |
spellingShingle |
Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents |
title_short |
Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents |
title_full |
Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents |
title_fullStr |
Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents |
title_full_unstemmed |
Studies on enzyme action. XIX.—Urease: a selective enzyme. II.—Observations on accelerative and inhibitive agents |
title_sort |
studies on enzyme action. xix.—urease: a selective enzyme. ii.—observations on accelerative and inhibitive agents |
publisher |
The Royal Society |
publishDate |
1913 |
url |
http://dx.doi.org/10.1098/rspb.1913.0029 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.1913.0029 |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_source |
Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character volume 86, issue 588, page 328-343 ISSN 0950-1193 2053-9185 |
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https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rspb.1913.0029 |
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Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character |
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86 |
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588 |
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328 |
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343 |
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1800749994088595456 |