PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation
Bone cement is one of the materials used in orthopaedics that serves various functions, such as binding bone implants, replacing damaged bones and filling spaces within bones. Various materials have been used to synthesize bone cement, and one promising material for further research is fish bone was...
Published in: | Royal Society Open Science |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
The Royal Society
2024
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1098/rsos.231694 https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.231694 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.231694 |
id |
crroyalsociety:10.1098/rsos.231694 |
---|---|
record_format |
openpolar |
spelling |
crroyalsociety:10.1098/rsos.231694 2024-06-23T07:56:30+00:00 PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation Khoman, Gessica Aurel Kalijaga, Muhammad Harza Arbaha Aisah, Nuning Fidyaningsih, Riastuti Raharjo, Jarot Arjasa, Oka P. Prajatelistia, Ekavianty 2024 http://dx.doi.org/10.1098/rsos.231694 https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.231694 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.231694 en eng The Royal Society http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ Royal Society Open Science volume 11, issue 3 ISSN 2054-5703 journal-article 2024 crroyalsociety https://doi.org/10.1098/rsos.231694 2024-06-10T04:15:08Z Bone cement is one of the materials used in orthopaedics that serves various functions, such as binding bone implants, replacing damaged bones and filling spaces within bones. Various materials have been used to synthesize bone cement, and one promising material for further research is fish bone waste-based bone cement. This study investigates the potential of fish bone waste-based bone cement by incorporating nano fish bone (NFB) and L -arginine ( L -Arg) protein into polymethyl methacrylate (PMMA) to examine apatite growth. NFB derived from the Salmo salar fish positively influences osteoblast cell proliferation and differentiation, while L-Arg enhances biocompatibility and antibiotic properties. The NFB/L-Arg combination holds promise in accelerating new bone formation and cell growth, both of which are crucial for fracture healing and bone remodelling. Tensile strength tests reveal the superior performance of BC-PMMA-1-NFB/L-Arg (36.11 MPa) compared with commercial PMMA (32 MPa). Immersion tests with simulated body fluid (SBF) solution for 7 days reveal accelerated apatite layer formation, emphasizing the potential benefits of NFB/ L -Arg in bone cement applications. Article in Journal/Newspaper Salmo salar The Royal Society Royal Society Open Science 11 3 |
institution |
Open Polar |
collection |
The Royal Society |
op_collection_id |
crroyalsociety |
language |
English |
description |
Bone cement is one of the materials used in orthopaedics that serves various functions, such as binding bone implants, replacing damaged bones and filling spaces within bones. Various materials have been used to synthesize bone cement, and one promising material for further research is fish bone waste-based bone cement. This study investigates the potential of fish bone waste-based bone cement by incorporating nano fish bone (NFB) and L -arginine ( L -Arg) protein into polymethyl methacrylate (PMMA) to examine apatite growth. NFB derived from the Salmo salar fish positively influences osteoblast cell proliferation and differentiation, while L-Arg enhances biocompatibility and antibiotic properties. The NFB/L-Arg combination holds promise in accelerating new bone formation and cell growth, both of which are crucial for fracture healing and bone remodelling. Tensile strength tests reveal the superior performance of BC-PMMA-1-NFB/L-Arg (36.11 MPa) compared with commercial PMMA (32 MPa). Immersion tests with simulated body fluid (SBF) solution for 7 days reveal accelerated apatite layer formation, emphasizing the potential benefits of NFB/ L -Arg in bone cement applications. |
format |
Article in Journal/Newspaper |
author |
Khoman, Gessica Aurel Kalijaga, Muhammad Harza Arbaha Aisah, Nuning Fidyaningsih, Riastuti Raharjo, Jarot Arjasa, Oka P. Prajatelistia, Ekavianty |
spellingShingle |
Khoman, Gessica Aurel Kalijaga, Muhammad Harza Arbaha Aisah, Nuning Fidyaningsih, Riastuti Raharjo, Jarot Arjasa, Oka P. Prajatelistia, Ekavianty PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation |
author_facet |
Khoman, Gessica Aurel Kalijaga, Muhammad Harza Arbaha Aisah, Nuning Fidyaningsih, Riastuti Raharjo, Jarot Arjasa, Oka P. Prajatelistia, Ekavianty |
author_sort |
Khoman, Gessica Aurel |
title |
PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation |
title_short |
PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation |
title_full |
PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation |
title_fullStr |
PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation |
title_full_unstemmed |
PMMA bone cement with L -arginine/nano fish bone nanocomplex for apatite formation |
title_sort |
pmma bone cement with l -arginine/nano fish bone nanocomplex for apatite formation |
publisher |
The Royal Society |
publishDate |
2024 |
url |
http://dx.doi.org/10.1098/rsos.231694 https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.231694 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.231694 |
genre |
Salmo salar |
genre_facet |
Salmo salar |
op_source |
Royal Society Open Science volume 11, issue 3 ISSN 2054-5703 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1098/rsos.231694 |
container_title |
Royal Society Open Science |
container_volume |
11 |
container_issue |
3 |
_version_ |
1802649612137267200 |