Swimming exercise enhances brain plasticity in fish
It is well-established that sustained exercise training can enhance brain plasticity and boost cognitive performance in mammals, but this phenomenon has not received much attention in fish. The aim of this study was to determine whether sustained swimming exercise can enhance brain plasticity in juv...
Published in: | Royal Society Open Science |
---|---|
Main Authors: | , , , , |
Other Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
The Royal Society
2020
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1098/rsos.191640 https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191640 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.191640 |
id |
crroyalsociety:10.1098/rsos.191640 |
---|---|
record_format |
openpolar |
spelling |
crroyalsociety:10.1098/rsos.191640 2024-10-06T13:47:24+00:00 Swimming exercise enhances brain plasticity in fish Mes, Daan Palstra, Arjan P. Henkel, Christiaan V. Mayer, Ian Vindas, Marco A. Norges Forskningsråd European Cooperation in Science and Technology Horizon 2020 Framework Programme 2020 http://dx.doi.org/10.1098/rsos.191640 https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191640 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.191640 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Royal Society Open Science volume 7, issue 1, page 191640 ISSN 2054-5703 journal-article 2020 crroyalsociety https://doi.org/10.1098/rsos.191640 2024-09-09T06:01:28Z It is well-established that sustained exercise training can enhance brain plasticity and boost cognitive performance in mammals, but this phenomenon has not received much attention in fish. The aim of this study was to determine whether sustained swimming exercise can enhance brain plasticity in juvenile Atlantic salmon. Brain plasticity was assessed by both mapping the whole telencephalon transcriptome and conducting telencephalic region-specific microdissections on target genes. We found that 1772 transcripts were differentially expressed between the exercise and control groups. Gene ontology (GO) analysis identified 195 and 272 GO categories with a significant overrepresentation of up- or downregulated transcripts, respectively. A multitude of these GO categories was associated with neuronal excitability, neuronal signalling, cell proliferation and neurite outgrowth (i.e. cognition-related neuronal markers). Additionally, we found an increase in proliferating cell nuclear antigen ( pcna ) after both three and eight weeks of exercise in the equivalent to the hippocampus in fish. Furthermore, the expression of the neural plasticity markers synaptotagmin ( syt ) and brain-derived neurotrophic factor ( bdnf ) were also increased due to exercise in the equivalent to the lateral septum in fish. In conclusion, this is the first time that swimming exercise has been directly linked to increased telencephalic neurogenesis and neural plasticity in a teleost, and our results pave the way for future studies on exercise-induced neuroplasticity in fish. Article in Journal/Newspaper Atlantic salmon The Royal Society Royal Society Open Science 7 1 191640 |
institution |
Open Polar |
collection |
The Royal Society |
op_collection_id |
crroyalsociety |
language |
English |
description |
It is well-established that sustained exercise training can enhance brain plasticity and boost cognitive performance in mammals, but this phenomenon has not received much attention in fish. The aim of this study was to determine whether sustained swimming exercise can enhance brain plasticity in juvenile Atlantic salmon. Brain plasticity was assessed by both mapping the whole telencephalon transcriptome and conducting telencephalic region-specific microdissections on target genes. We found that 1772 transcripts were differentially expressed between the exercise and control groups. Gene ontology (GO) analysis identified 195 and 272 GO categories with a significant overrepresentation of up- or downregulated transcripts, respectively. A multitude of these GO categories was associated with neuronal excitability, neuronal signalling, cell proliferation and neurite outgrowth (i.e. cognition-related neuronal markers). Additionally, we found an increase in proliferating cell nuclear antigen ( pcna ) after both three and eight weeks of exercise in the equivalent to the hippocampus in fish. Furthermore, the expression of the neural plasticity markers synaptotagmin ( syt ) and brain-derived neurotrophic factor ( bdnf ) were also increased due to exercise in the equivalent to the lateral septum in fish. In conclusion, this is the first time that swimming exercise has been directly linked to increased telencephalic neurogenesis and neural plasticity in a teleost, and our results pave the way for future studies on exercise-induced neuroplasticity in fish. |
author2 |
Norges Forskningsråd European Cooperation in Science and Technology Horizon 2020 Framework Programme |
format |
Article in Journal/Newspaper |
author |
Mes, Daan Palstra, Arjan P. Henkel, Christiaan V. Mayer, Ian Vindas, Marco A. |
spellingShingle |
Mes, Daan Palstra, Arjan P. Henkel, Christiaan V. Mayer, Ian Vindas, Marco A. Swimming exercise enhances brain plasticity in fish |
author_facet |
Mes, Daan Palstra, Arjan P. Henkel, Christiaan V. Mayer, Ian Vindas, Marco A. |
author_sort |
Mes, Daan |
title |
Swimming exercise enhances brain plasticity in fish |
title_short |
Swimming exercise enhances brain plasticity in fish |
title_full |
Swimming exercise enhances brain plasticity in fish |
title_fullStr |
Swimming exercise enhances brain plasticity in fish |
title_full_unstemmed |
Swimming exercise enhances brain plasticity in fish |
title_sort |
swimming exercise enhances brain plasticity in fish |
publisher |
The Royal Society |
publishDate |
2020 |
url |
http://dx.doi.org/10.1098/rsos.191640 https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191640 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.191640 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Royal Society Open Science volume 7, issue 1, page 191640 ISSN 2054-5703 |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rsos.191640 |
container_title |
Royal Society Open Science |
container_volume |
7 |
container_issue |
1 |
container_start_page |
191640 |
_version_ |
1812175623762739200 |