Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates
Infectious salmon anaemia (ISA) is an important infectious disease in Atlantic salmon farming causing recurrent epidemic outbreaks worldwide. The focus of this paper is on tracing the spread of ISA among Norwegian salmon farms. To trace transmission pathways for the ISA virus (ISAV), we use phylogen...
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crroyalsociety:10.1098/rsif.2010.0737 2024-06-02T08:03:42+00:00 Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates Aldrin, M. Lyngstad, T. M. Kristoffersen, A. B. Storvik, B. Borgan, Ø. Jansen, P. A. 2011 http://dx.doi.org/10.1098/rsif.2010.0737 https://royalsocietypublishing.org/doi/pdf/10.1098/rsif.2010.0737 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsif.2010.0737 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Journal of The Royal Society Interface volume 8, issue 62, page 1346-1356 ISSN 1742-5689 1742-5662 journal-article 2011 crroyalsociety https://doi.org/10.1098/rsif.2010.0737 2024-05-07T14:16:18Z Infectious salmon anaemia (ISA) is an important infectious disease in Atlantic salmon farming causing recurrent epidemic outbreaks worldwide. The focus of this paper is on tracing the spread of ISA among Norwegian salmon farms. To trace transmission pathways for the ISA virus (ISAV), we use phylogenetic relationships between virus isolates in combination with space–time data on disease occurrences. The rate of ISA infection of salmon farms is modelled stochastically, where seaway distances between farms and genetic distances between ISAV isolates from infected farms play prominent roles. The model was fitted to data covering all cohorts of farmed salmon and the history of all farms with ISA between 2003 and summer 2009. Both seaway and genetic distances were significantly associated with the rate of ISA infection. The fitted model predicts that the risk of infection from a neighbourhood infectious farm decreases with increasing seaway distance between the two farms. Furthermore, for a given infected farm with a given ISAV genotype, the source of infection is significantly more likely to be ISAV of a small genetic distance than of moderate or large genetic distances. Nearly half of the farms with ISA in the investigated period are predicted to have been infected by an infectious farm in their neighbourhood, whereas the remaining half of the infected farms had unknown sources. For many of the neighbourhood infected farms, it was possible to point out one or a few infectious farms as the most probable sources of infection. This makes it possible to map probable infection pathways. Article in Journal/Newspaper Atlantic salmon The Royal Society Journal of The Royal Society Interface 8 62 1346 1356 |
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Open Polar |
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The Royal Society |
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crroyalsociety |
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English |
description |
Infectious salmon anaemia (ISA) is an important infectious disease in Atlantic salmon farming causing recurrent epidemic outbreaks worldwide. The focus of this paper is on tracing the spread of ISA among Norwegian salmon farms. To trace transmission pathways for the ISA virus (ISAV), we use phylogenetic relationships between virus isolates in combination with space–time data on disease occurrences. The rate of ISA infection of salmon farms is modelled stochastically, where seaway distances between farms and genetic distances between ISAV isolates from infected farms play prominent roles. The model was fitted to data covering all cohorts of farmed salmon and the history of all farms with ISA between 2003 and summer 2009. Both seaway and genetic distances were significantly associated with the rate of ISA infection. The fitted model predicts that the risk of infection from a neighbourhood infectious farm decreases with increasing seaway distance between the two farms. Furthermore, for a given infected farm with a given ISAV genotype, the source of infection is significantly more likely to be ISAV of a small genetic distance than of moderate or large genetic distances. Nearly half of the farms with ISA in the investigated period are predicted to have been infected by an infectious farm in their neighbourhood, whereas the remaining half of the infected farms had unknown sources. For many of the neighbourhood infected farms, it was possible to point out one or a few infectious farms as the most probable sources of infection. This makes it possible to map probable infection pathways. |
format |
Article in Journal/Newspaper |
author |
Aldrin, M. Lyngstad, T. M. Kristoffersen, A. B. Storvik, B. Borgan, Ø. Jansen, P. A. |
spellingShingle |
Aldrin, M. Lyngstad, T. M. Kristoffersen, A. B. Storvik, B. Borgan, Ø. Jansen, P. A. Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
author_facet |
Aldrin, M. Lyngstad, T. M. Kristoffersen, A. B. Storvik, B. Borgan, Ø. Jansen, P. A. |
author_sort |
Aldrin, M. |
title |
Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
title_short |
Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
title_full |
Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
title_fullStr |
Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
title_full_unstemmed |
Modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
title_sort |
modelling the spread of infectious salmon anaemia among salmon farms based on seaway distances between farms and genetic relationships between infectious salmon anaemia virus isolates |
publisher |
The Royal Society |
publishDate |
2011 |
url |
http://dx.doi.org/10.1098/rsif.2010.0737 https://royalsocietypublishing.org/doi/pdf/10.1098/rsif.2010.0737 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsif.2010.0737 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Journal of The Royal Society Interface volume 8, issue 62, page 1346-1356 ISSN 1742-5689 1742-5662 |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rsif.2010.0737 |
container_title |
Journal of The Royal Society Interface |
container_volume |
8 |
container_issue |
62 |
container_start_page |
1346 |
op_container_end_page |
1356 |
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1800748304864116736 |