Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species
The continuous increase of anthropogenic CO 2 in the atmosphere resulting in ocean acidification has been reported to affect brain function in some fishes. During adulthood, cell proliferation is fundamental for fish brain growth and for it to adapt in response to external stimuli, such as environme...
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crroyalsociety:10.1098/rsbl.2017.0240 2024-09-15T18:28:15+00:00 Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species Lai, Floriana Fagernes, Cathrine E. Bernier, Nicholas J. Miller, Gabrielle M. Munday, Philip L. Jutfelt, Fredrik Nilsson, Göran E. The University of Oslo Australian Coral Reef Society the ARC Centre of Excellence for Coral Reef Studies GBRMPA Science for Management Awards the Swedish Research Council the Swedish research council FORMAS Sea World Research and Rescue Foundation 2017 http://dx.doi.org/10.1098/rsbl.2017.0240 https://royalsocietypublishing.org/doi/pdf/10.1098/rsbl.2017.0240 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsbl.2017.0240 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Biology Letters volume 13, issue 8, page 20170240 ISSN 1744-9561 1744-957X journal-article 2017 crroyalsociety https://doi.org/10.1098/rsbl.2017.0240 2024-08-12T04:27:43Z The continuous increase of anthropogenic CO 2 in the atmosphere resulting in ocean acidification has been reported to affect brain function in some fishes. During adulthood, cell proliferation is fundamental for fish brain growth and for it to adapt in response to external stimuli, such as environmental changes. Here we report the first expression study of genes regulating neurogenesis and neuroplasticity in brains of three-spined stickleback ( Gasterosteus aculeatus ), cinnamon anemonefish ( Amphiprion melanopus ) and spiny damselfish ( Acanthochromis polyacanthus ) exposed to elevated CO 2 . The mRNA expression levels of the neurogenic differentiation factor (NeuroD) and doublecortin (DCX) were upregulated in three-spined stickleback exposed to high-CO 2 compared with controls, while no changes were detected in the other species. The mRNA expression levels of the proliferating cell nuclear antigen (PCNA) and the brain-derived neurotrophic factor (BDNF) remained unaffected in the high-CO 2 exposed groups compared to the control in all three species. These results indicate a species-specific regulation of genes involved in neurogenesis in response to elevated ambient CO 2 levels. The higher expression of NeuroD and DCX mRNA transcripts in the brain of high-CO 2 –exposed three-spined stickleback, together with the lack of effects on mRNA levels in cinnamon anemonefish and spiny damselfish, indicate differences in coping mechanisms among fish in response to the predicted-future CO 2 level. Article in Journal/Newspaper Ocean acidification The Royal Society Biology Letters 13 8 20170240 |
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The Royal Society |
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crroyalsociety |
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English |
description |
The continuous increase of anthropogenic CO 2 in the atmosphere resulting in ocean acidification has been reported to affect brain function in some fishes. During adulthood, cell proliferation is fundamental for fish brain growth and for it to adapt in response to external stimuli, such as environmental changes. Here we report the first expression study of genes regulating neurogenesis and neuroplasticity in brains of three-spined stickleback ( Gasterosteus aculeatus ), cinnamon anemonefish ( Amphiprion melanopus ) and spiny damselfish ( Acanthochromis polyacanthus ) exposed to elevated CO 2 . The mRNA expression levels of the neurogenic differentiation factor (NeuroD) and doublecortin (DCX) were upregulated in three-spined stickleback exposed to high-CO 2 compared with controls, while no changes were detected in the other species. The mRNA expression levels of the proliferating cell nuclear antigen (PCNA) and the brain-derived neurotrophic factor (BDNF) remained unaffected in the high-CO 2 exposed groups compared to the control in all three species. These results indicate a species-specific regulation of genes involved in neurogenesis in response to elevated ambient CO 2 levels. The higher expression of NeuroD and DCX mRNA transcripts in the brain of high-CO 2 –exposed three-spined stickleback, together with the lack of effects on mRNA levels in cinnamon anemonefish and spiny damselfish, indicate differences in coping mechanisms among fish in response to the predicted-future CO 2 level. |
author2 |
The University of Oslo Australian Coral Reef Society the ARC Centre of Excellence for Coral Reef Studies GBRMPA Science for Management Awards the Swedish Research Council the Swedish research council FORMAS Sea World Research and Rescue Foundation |
format |
Article in Journal/Newspaper |
author |
Lai, Floriana Fagernes, Cathrine E. Bernier, Nicholas J. Miller, Gabrielle M. Munday, Philip L. Jutfelt, Fredrik Nilsson, Göran E. |
spellingShingle |
Lai, Floriana Fagernes, Cathrine E. Bernier, Nicholas J. Miller, Gabrielle M. Munday, Philip L. Jutfelt, Fredrik Nilsson, Göran E. Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species |
author_facet |
Lai, Floriana Fagernes, Cathrine E. Bernier, Nicholas J. Miller, Gabrielle M. Munday, Philip L. Jutfelt, Fredrik Nilsson, Göran E. |
author_sort |
Lai, Floriana |
title |
Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species |
title_short |
Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species |
title_full |
Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species |
title_fullStr |
Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species |
title_full_unstemmed |
Responses of neurogenesis and neuroplasticity related genes to elevated CO 2 levels in the brain of three teleost species |
title_sort |
responses of neurogenesis and neuroplasticity related genes to elevated co 2 levels in the brain of three teleost species |
publisher |
The Royal Society |
publishDate |
2017 |
url |
http://dx.doi.org/10.1098/rsbl.2017.0240 https://royalsocietypublishing.org/doi/pdf/10.1098/rsbl.2017.0240 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsbl.2017.0240 |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_source |
Biology Letters volume 13, issue 8, page 20170240 ISSN 1744-9561 1744-957X |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rsbl.2017.0240 |
container_title |
Biology Letters |
container_volume |
13 |
container_issue |
8 |
container_start_page |
20170240 |
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1810469598626054144 |