Cardiac myoglobin deficit has evolved repeatedly in teleost fishes
Myoglobin (Mb) is the classic vertebrate oxygen-binding protein present in aerobic striated muscles. It functions principally in oxygen delivery and provides muscle with its characteristic red colour. Members of the Antarctic icefish family (Channichthyidae) are widely thought to be extraordinary fo...
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crroyalsociety:10.1098/rsbl.2014.0225 2024-09-30T14:25:18+00:00 Cardiac myoglobin deficit has evolved repeatedly in teleost fishes Macqueen, Daniel J. Garcia de la serrana, Daniel Johnston, Ian A. 2014 http://dx.doi.org/10.1098/rsbl.2014.0225 https://royalsocietypublishing.org/doi/pdf/10.1098/rsbl.2014.0225 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsbl.2014.0225 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Biology Letters volume 10, issue 6, page 20140225 ISSN 1744-9561 1744-957X journal-article 2014 crroyalsociety https://doi.org/10.1098/rsbl.2014.0225 2024-09-02T04:21:04Z Myoglobin (Mb) is the classic vertebrate oxygen-binding protein present in aerobic striated muscles. It functions principally in oxygen delivery and provides muscle with its characteristic red colour. Members of the Antarctic icefish family (Channichthyidae) are widely thought to be extraordinary for lacking cardiac Mb expression, a fact that has been attributed to their low metabolic rate and unusual evolutionary history. Here, we report that cardiac Mb deficit, associated with pale heart colour, has evolved repeatedly during teleost evolution. This trait affects both gill- and air-breathing species from temperate to tropical habitats across a full range of salinities. Cardiac Mb deficit results from total pseudogenization in three-spined stickleback and is associated with a massive reduction in mRNA level in two species that evidently retain functional Mb. The results suggest that near or complete absence of Mb-assisted oxygen delivery to heart muscle is a common facet of teleost biodiversity, even affecting lineages with notable oxygen demands. We suggest that Mb deficit may affect how different teleost species deal with increased tissue oxygen demands arising under climate change. Article in Journal/Newspaper Antarc* Antarctic Icefish The Royal Society Antarctic The Antarctic Biology Letters 10 6 20140225 |
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Open Polar |
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The Royal Society |
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crroyalsociety |
language |
English |
description |
Myoglobin (Mb) is the classic vertebrate oxygen-binding protein present in aerobic striated muscles. It functions principally in oxygen delivery and provides muscle with its characteristic red colour. Members of the Antarctic icefish family (Channichthyidae) are widely thought to be extraordinary for lacking cardiac Mb expression, a fact that has been attributed to their low metabolic rate and unusual evolutionary history. Here, we report that cardiac Mb deficit, associated with pale heart colour, has evolved repeatedly during teleost evolution. This trait affects both gill- and air-breathing species from temperate to tropical habitats across a full range of salinities. Cardiac Mb deficit results from total pseudogenization in three-spined stickleback and is associated with a massive reduction in mRNA level in two species that evidently retain functional Mb. The results suggest that near or complete absence of Mb-assisted oxygen delivery to heart muscle is a common facet of teleost biodiversity, even affecting lineages with notable oxygen demands. We suggest that Mb deficit may affect how different teleost species deal with increased tissue oxygen demands arising under climate change. |
format |
Article in Journal/Newspaper |
author |
Macqueen, Daniel J. Garcia de la serrana, Daniel Johnston, Ian A. |
spellingShingle |
Macqueen, Daniel J. Garcia de la serrana, Daniel Johnston, Ian A. Cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
author_facet |
Macqueen, Daniel J. Garcia de la serrana, Daniel Johnston, Ian A. |
author_sort |
Macqueen, Daniel J. |
title |
Cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
title_short |
Cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
title_full |
Cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
title_fullStr |
Cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
title_full_unstemmed |
Cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
title_sort |
cardiac myoglobin deficit has evolved repeatedly in teleost fishes |
publisher |
The Royal Society |
publishDate |
2014 |
url |
http://dx.doi.org/10.1098/rsbl.2014.0225 https://royalsocietypublishing.org/doi/pdf/10.1098/rsbl.2014.0225 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsbl.2014.0225 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic Icefish |
genre_facet |
Antarc* Antarctic Icefish |
op_source |
Biology Letters volume 10, issue 6, page 20140225 ISSN 1744-9561 1744-957X |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rsbl.2014.0225 |
container_title |
Biology Letters |
container_volume |
10 |
container_issue |
6 |
container_start_page |
20140225 |
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1811644296939438080 |