Positive selection on the killer whale mitogenome
Mitochondria produce up to 95 per cent of the eukaryotic cell's energy. The coding genes of the mitochondrial DNA may therefore evolve under selection owing to metabolic requirements. The killer whale, Orcinus orca , is polymorphic, has a global distribution and occupies a range of ecological n...
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crroyalsociety:10.1098/rsbl.2010.0638 2024-09-09T19:12:04+00:00 Positive selection on the killer whale mitogenome Foote, Andrew D. Morin, Phillip A. Durban, John W. Pitman, Robert L. Wade, Paul Willerslev, Eske Gilbert, M. Thomas P. da Fonseca, Rute R. 2010 http://dx.doi.org/10.1098/rsbl.2010.0638 https://royalsocietypublishing.org/doi/pdf/10.1098/rsbl.2010.0638 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsbl.2010.0638 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Biology Letters volume 7, issue 1, page 116-118 ISSN 1744-9561 1744-957X journal-article 2010 crroyalsociety https://doi.org/10.1098/rsbl.2010.0638 2024-08-26T04:21:02Z Mitochondria produce up to 95 per cent of the eukaryotic cell's energy. The coding genes of the mitochondrial DNA may therefore evolve under selection owing to metabolic requirements. The killer whale, Orcinus orca , is polymorphic, has a global distribution and occupies a range of ecological niches. It is therefore a suitable organism for testing this hypothesis. We compared a global dataset of the complete mitochondrial genomes of 139 individuals for amino acid changes that were associated with radical physico-chemical property changes and were influenced by positive selection. Two such selected non-synonymous amino acid changes were found; one in each of two ecotypes that inhabit the Antarctic pack ice. Both substitutions were associated with changes in local polarity, increased steric constraints and α-helical tendencies that could influence overall metabolic performance, suggesting a functional change. Article in Journal/Newspaper Antarc* Antarctic Killer Whale Orca Orcinus orca Killer whale The Royal Society Antarctic The Antarctic Biology Letters 7 1 116 118 |
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Open Polar |
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The Royal Society |
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crroyalsociety |
language |
English |
description |
Mitochondria produce up to 95 per cent of the eukaryotic cell's energy. The coding genes of the mitochondrial DNA may therefore evolve under selection owing to metabolic requirements. The killer whale, Orcinus orca , is polymorphic, has a global distribution and occupies a range of ecological niches. It is therefore a suitable organism for testing this hypothesis. We compared a global dataset of the complete mitochondrial genomes of 139 individuals for amino acid changes that were associated with radical physico-chemical property changes and were influenced by positive selection. Two such selected non-synonymous amino acid changes were found; one in each of two ecotypes that inhabit the Antarctic pack ice. Both substitutions were associated with changes in local polarity, increased steric constraints and α-helical tendencies that could influence overall metabolic performance, suggesting a functional change. |
format |
Article in Journal/Newspaper |
author |
Foote, Andrew D. Morin, Phillip A. Durban, John W. Pitman, Robert L. Wade, Paul Willerslev, Eske Gilbert, M. Thomas P. da Fonseca, Rute R. |
spellingShingle |
Foote, Andrew D. Morin, Phillip A. Durban, John W. Pitman, Robert L. Wade, Paul Willerslev, Eske Gilbert, M. Thomas P. da Fonseca, Rute R. Positive selection on the killer whale mitogenome |
author_facet |
Foote, Andrew D. Morin, Phillip A. Durban, John W. Pitman, Robert L. Wade, Paul Willerslev, Eske Gilbert, M. Thomas P. da Fonseca, Rute R. |
author_sort |
Foote, Andrew D. |
title |
Positive selection on the killer whale mitogenome |
title_short |
Positive selection on the killer whale mitogenome |
title_full |
Positive selection on the killer whale mitogenome |
title_fullStr |
Positive selection on the killer whale mitogenome |
title_full_unstemmed |
Positive selection on the killer whale mitogenome |
title_sort |
positive selection on the killer whale mitogenome |
publisher |
The Royal Society |
publishDate |
2010 |
url |
http://dx.doi.org/10.1098/rsbl.2010.0638 https://royalsocietypublishing.org/doi/pdf/10.1098/rsbl.2010.0638 https://royalsocietypublishing.org/doi/full-xml/10.1098/rsbl.2010.0638 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic Killer Whale Orca Orcinus orca Killer whale |
genre_facet |
Antarc* Antarctic Killer Whale Orca Orcinus orca Killer whale |
op_source |
Biology Letters volume 7, issue 1, page 116-118 ISSN 1744-9561 1744-957X |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rsbl.2010.0638 |
container_title |
Biology Letters |
container_volume |
7 |
container_issue |
1 |
container_start_page |
116 |
op_container_end_page |
118 |
_version_ |
1809752516866342912 |