Identification and bioactivity evaluation of secondary metabolites from Antarctic-derived Penicillium chrysogenum CCTCC M 2020019

• Published in: RSC Advances
• Main Authors: Khan, Imran, Zhang, Haibo, Liu, Wei, Zhang, Liping, Peng, Fang, Chen, Yuchan, Zhang, Qingbo, Zhang, Guangtao, Zhang, Weimin, Zhang, Changsheng
• Other Authors: National Natural Science Foundation of China, National Basic Research Program of China
• Format: Article in Journal/Newspaper
• Language: English
• Published: Royal Society of Chemistry (RSC) 2020
• Subjects: Antarc*; Antarctic
• Online Access: http://dx.doi.org/10.1039/d0ra03529g; http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA03529G

The unprecedented eight-membered heterocyclic chrysonin ( 1 ) was isolated from an Antarctic fungus that also produced xanthocillins 4 and 5 as potent inhibitors against Gram-negative pathogens.