The effect of imidazolium cations on the structure and activity of the Candida antarctica Lipase B enzyme in ionic liquids

• Published in: Physical Chemistry Chemical Physics
• Main Authors: Kim, Ho Shin, Eom, Doyoung, Koo, Yoon-Mo, Yingling, Yaroslava G.
• Other Authors: Inha University, Korea Coast Guard, Division of Materials Research
• Format: Article in Journal/Newspaper
• Language: English
• Published: Royal Society of Chemistry (RSC) 2016
• Subjects: Antarc*; Antarctica
• Online Access: http://dx.doi.org/10.1039/c6cp02355j; http://pubs.rsc.org/en/content/articlepdf/2016/CP/C6CP02355J

To understand how cations affect the enzyme structure and activity of Candida antarctica Lipase B, we performed MD simulations of CALB in four types of ionic liquids with varying sizes of cations and correlated the results with the experimental data.