A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1.
The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this o...
Published in: | Journal of Experimental Medicine |
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Language: | English |
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Rockefeller University Press
1989
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Online Access: | http://dx.doi.org/10.1084/jem.169.4.1461 https://rupress.org/jem/article-pdf/169/4/1461/1669703/1461.pdf |
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crrockefelleruni:10.1084/jem.169.4.1461 2024-06-02T08:14:52+00:00 A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. Butterfield, K Fathman, C G Budd, R C 1989 http://dx.doi.org/10.1084/jem.169.4.1461 https://rupress.org/jem/article-pdf/169/4/1461/1669703/1461.pdf en eng Rockefeller University Press The Journal of experimental medicine volume 169, issue 4, page 1461-1466 ISSN 0022-1007 1540-9538 journal-article 1989 crrockefelleruni https://doi.org/10.1084/jem.169.4.1461 2024-05-07T14:15:15Z The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset. Article in Journal/Newspaper Sperm whale Rockefeller University Press Keyhole ENVELOPE(-67.338,-67.338,-68.785,-68.785) Journal of Experimental Medicine 169 4 1461 1466 |
institution |
Open Polar |
collection |
Rockefeller University Press |
op_collection_id |
crrockefelleruni |
language |
English |
description |
The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset. |
format |
Article in Journal/Newspaper |
author |
Butterfield, K Fathman, C G Budd, R C |
spellingShingle |
Butterfield, K Fathman, C G Budd, R C A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. |
author_facet |
Butterfield, K Fathman, C G Budd, R C |
author_sort |
Butterfield, K |
title |
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. |
title_short |
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. |
title_full |
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. |
title_fullStr |
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. |
title_full_unstemmed |
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1. |
title_sort |
subset of memory cd4+ helper t lymphocytes identified by expression of pgp-1. |
publisher |
Rockefeller University Press |
publishDate |
1989 |
url |
http://dx.doi.org/10.1084/jem.169.4.1461 https://rupress.org/jem/article-pdf/169/4/1461/1669703/1461.pdf |
long_lat |
ENVELOPE(-67.338,-67.338,-68.785,-68.785) |
geographic |
Keyhole |
geographic_facet |
Keyhole |
genre |
Sperm whale |
genre_facet |
Sperm whale |
op_source |
The Journal of experimental medicine volume 169, issue 4, page 1461-1466 ISSN 0022-1007 1540-9538 |
op_doi |
https://doi.org/10.1084/jem.169.4.1461 |
container_title |
Journal of Experimental Medicine |
container_volume |
169 |
container_issue |
4 |
container_start_page |
1461 |
op_container_end_page |
1466 |
_version_ |
1800738871255760896 |