Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields ca...
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Portland Press Ltd.
1969
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Online Access: | http://dx.doi.org/10.1042/bj1140703 https://portlandpress.com/biochemj/article-pdf/114/4/703/765351/bj1140703.pdf |
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crportlandpress:10.1042/bj1140703 2024-06-09T07:45:20+00:00 Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay 1969 http://dx.doi.org/10.1042/bj1140703 https://portlandpress.com/biochemj/article-pdf/114/4/703/765351/bj1140703.pdf en eng Portland Press Ltd. Biochemical Journal volume 114, issue 4, page 703-705 ISSN 0306-3283 journal-article 1969 crportlandpress https://doi.org/10.1042/bj1140703 2024-05-16T14:10:05Z Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields carbonic acid (HCO3− and H+), which dissociates to form molecular carbon dioxide. Brain carbonic anhydrase facilitates the formation of carbon dioxide from the decarboxylation products. Article in Journal/Newspaper Carbonic acid Portland Press Biochemical Journal 114 4 703 705 |
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Open Polar |
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Portland Press |
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crportlandpress |
language |
English |
description |
Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields carbonic acid (HCO3− and H+), which dissociates to form molecular carbon dioxide. Brain carbonic anhydrase facilitates the formation of carbon dioxide from the decarboxylation products. |
format |
Article in Journal/Newspaper |
author |
Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay |
spellingShingle |
Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
author_facet |
Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay |
author_sort |
Severinghaus, John W. |
title |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_short |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_full |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_fullStr |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_full_unstemmed |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_sort |
carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
publisher |
Portland Press Ltd. |
publishDate |
1969 |
url |
http://dx.doi.org/10.1042/bj1140703 https://portlandpress.com/biochemj/article-pdf/114/4/703/765351/bj1140703.pdf |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_source |
Biochemical Journal volume 114, issue 4, page 703-705 ISSN 0306-3283 |
op_doi |
https://doi.org/10.1042/bj1140703 |
container_title |
Biochemical Journal |
container_volume |
114 |
container_issue |
4 |
container_start_page |
703 |
op_container_end_page |
705 |
_version_ |
1801374628845715456 |