Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations
Abstract New Zealand, Australia, Iceland, and Taiwan all saw success in controlling their first waves of Coronavirus Disease 2019 (COVID-19). As islands, they make excellent case studies for exploring the effects of international travel and human movement on the spread of COVID-19. We employed a ran...
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Oxford University Press (OUP)
2021
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Online Access: | http://dx.doi.org/10.1093/ve/veab052 http://academic.oup.com/ve/advance-article-pdf/doi/10.1093/ve/veab052/38876584/veab052.pdf https://academic.oup.com/ve/article-pdf/7/2/veab052/50058354/veab052.pdf |
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croxfordunivpr:10.1093/ve/veab052 2024-06-23T07:54:03+00:00 Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations Douglas, Jordan Mendes, Fábio K Bouckaert, Remco Xie, Dong Jiménez-Silva, Cinthy L Swanepoel, Christiaan de Ligt, Joep Ren, Xiaoyun Storey, Matt Hadfield, James Simpson, Colin R Geoghegan, Jemma L Drummond, Alexei J Welch, David New Zealand Ministry of Health New Zealand Ministry of Business, Innovation & Employment Royal Society Te Aparangi 2021 http://dx.doi.org/10.1093/ve/veab052 http://academic.oup.com/ve/advance-article-pdf/doi/10.1093/ve/veab052/38876584/veab052.pdf https://academic.oup.com/ve/article-pdf/7/2/veab052/50058354/veab052.pdf en eng Oxford University Press (OUP) https://creativecommons.org/licenses/by/4.0/ Virus Evolution volume 7, issue 2 ISSN 2057-1577 journal-article 2021 croxfordunivpr https://doi.org/10.1093/ve/veab052 2024-06-04T06:15:25Z Abstract New Zealand, Australia, Iceland, and Taiwan all saw success in controlling their first waves of Coronavirus Disease 2019 (COVID-19). As islands, they make excellent case studies for exploring the effects of international travel and human movement on the spread of COVID-19. We employed a range of robust phylodynamic methods and genome subsampling strategies to infer the epidemiological history of Severe acute respiratory syndrome coronavirus 2 in these four countries. We compared these results to transmission clusters identified by the New Zealand Ministry of Health by contact tracing strategies. We estimated the effective reproduction number of COVID-19 as 1–1.4 during early stages of the pandemic and show that it declined below 1 as human movement was restricted. We also showed that this disease was introduced many times into each country and that introductions slowed down markedly following the reduction of international travel in mid-March 2020. Finally, we confirmed that New Zealand transmission clusters identified via standard health surveillance strategies largely agree with those defined by genomic data. We have demonstrated how the use of genomic data and computational biology methods can assist health officials in characterising the epidemiology of viral epidemics and for contact tracing. Article in Journal/Newspaper Iceland Oxford University Press New Zealand Virus Evolution |
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Open Polar |
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Oxford University Press |
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croxfordunivpr |
language |
English |
description |
Abstract New Zealand, Australia, Iceland, and Taiwan all saw success in controlling their first waves of Coronavirus Disease 2019 (COVID-19). As islands, they make excellent case studies for exploring the effects of international travel and human movement on the spread of COVID-19. We employed a range of robust phylodynamic methods and genome subsampling strategies to infer the epidemiological history of Severe acute respiratory syndrome coronavirus 2 in these four countries. We compared these results to transmission clusters identified by the New Zealand Ministry of Health by contact tracing strategies. We estimated the effective reproduction number of COVID-19 as 1–1.4 during early stages of the pandemic and show that it declined below 1 as human movement was restricted. We also showed that this disease was introduced many times into each country and that introductions slowed down markedly following the reduction of international travel in mid-March 2020. Finally, we confirmed that New Zealand transmission clusters identified via standard health surveillance strategies largely agree with those defined by genomic data. We have demonstrated how the use of genomic data and computational biology methods can assist health officials in characterising the epidemiology of viral epidemics and for contact tracing. |
author2 |
New Zealand Ministry of Health New Zealand Ministry of Business, Innovation & Employment Royal Society Te Aparangi |
format |
Article in Journal/Newspaper |
author |
Douglas, Jordan Mendes, Fábio K Bouckaert, Remco Xie, Dong Jiménez-Silva, Cinthy L Swanepoel, Christiaan de Ligt, Joep Ren, Xiaoyun Storey, Matt Hadfield, James Simpson, Colin R Geoghegan, Jemma L Drummond, Alexei J Welch, David |
spellingShingle |
Douglas, Jordan Mendes, Fábio K Bouckaert, Remco Xie, Dong Jiménez-Silva, Cinthy L Swanepoel, Christiaan de Ligt, Joep Ren, Xiaoyun Storey, Matt Hadfield, James Simpson, Colin R Geoghegan, Jemma L Drummond, Alexei J Welch, David Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations |
author_facet |
Douglas, Jordan Mendes, Fábio K Bouckaert, Remco Xie, Dong Jiménez-Silva, Cinthy L Swanepoel, Christiaan de Ligt, Joep Ren, Xiaoyun Storey, Matt Hadfield, James Simpson, Colin R Geoghegan, Jemma L Drummond, Alexei J Welch, David |
author_sort |
Douglas, Jordan |
title |
Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations |
title_short |
Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations |
title_full |
Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations |
title_fullStr |
Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations |
title_full_unstemmed |
Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations |
title_sort |
phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of covid-19 in four island nations |
publisher |
Oxford University Press (OUP) |
publishDate |
2021 |
url |
http://dx.doi.org/10.1093/ve/veab052 http://academic.oup.com/ve/advance-article-pdf/doi/10.1093/ve/veab052/38876584/veab052.pdf https://academic.oup.com/ve/article-pdf/7/2/veab052/50058354/veab052.pdf |
geographic |
New Zealand |
geographic_facet |
New Zealand |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Virus Evolution volume 7, issue 2 ISSN 2057-1577 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1093/ve/veab052 |
container_title |
Virus Evolution |
_version_ |
1802645986745516032 |