The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome
Abstract Background This study was carried out to determine the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. It was a prospective randomized study that performed on twenty cases with idiopathic C...
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croxfordunivpr:10.1093/qjmed/hcaa064.009 2023-05-15T16:01:42+02:00 The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome Elsebaie, M A Elarousi, N H Elattar, E A Mohamed, A A 2020 http://dx.doi.org/10.1093/qjmed/hcaa064.009 http://academic.oup.com/qjmed/article-pdf/113/Supplement_1/hcaa064.009/33164082/hcaa064.009.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model QJM: An International Journal of Medicine volume 113, issue Supplement_1 ISSN 1460-2725 1460-2393 General Medicine journal-article 2020 croxfordunivpr https://doi.org/10.1093/qjmed/hcaa064.009 2022-04-15T06:33:20Z Abstract Background This study was carried out to determine the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. It was a prospective randomized study that performed on twenty cases with idiopathic CTS; they were diagnosed clinically and electrophysiologically according to AANEM criteria (2002). Objectives To study the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. Patients and Methods It was a prospective randomized study that performed on twenty cases with idiopathic CTS; they were diagnosed clinically and electrophysiologically according to AANEM criteria (2002). All patients received PIT sessions. The injection done once weekly for 6 weeks. They were assessed before and after the treatment sessions by the following: provocative tests (Tinel, phalen and reverse phalen), clinical assessment scale (VAS and BCTQ"SSS, FSS") and nerve conduction study. Results By the end of the treatment, All provocative tests & All assessment scores showed a highly statistical significant difference (p > 0.01). Regarding sensory examination: night parethesia, hand pain and tingling &numbness showed a highly statistical significant difference (p > 0.01). Our results as regard nerve conduction studies of DML, sensory CV and DSL —difference between median and ulnar nerves showed that there was a statistical significant difference with improvement and there was a highly statistical significant difference with improvement as regard DSL and DML-difference between median and ulnar nerves. Before treatment VAS has a positive correlation with DML (r = 0.448, P < 0.05), another significant positive correlation was found between SSS and DSI (r = 0.45 , p < 0.05), but there was a negative correlation between VAS and the following MCV (r=-0.536, p < 0.05) and SCV (r= -0.462, p < 0.05). After treatment there was a negative correlation between VAS and the following SCV (r = -0.528, p < 0.05) and MCV (r= -0.618, p- 0,01 ). Conclusion Our study revealed that PIT Of D5W is an effective treatment for patients with mild to moderate CIS. Article in Journal/Newspaper DML Oxford University Press (via Crossref) QJM: An International Journal of Medicine 113 Supplement_1 |
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Open Polar |
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Oxford University Press (via Crossref) |
op_collection_id |
croxfordunivpr |
language |
English |
topic |
General Medicine |
spellingShingle |
General Medicine Elsebaie, M A Elarousi, N H Elattar, E A Mohamed, A A The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome |
topic_facet |
General Medicine |
description |
Abstract Background This study was carried out to determine the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. It was a prospective randomized study that performed on twenty cases with idiopathic CTS; they were diagnosed clinically and electrophysiologically according to AANEM criteria (2002). Objectives To study the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. Patients and Methods It was a prospective randomized study that performed on twenty cases with idiopathic CTS; they were diagnosed clinically and electrophysiologically according to AANEM criteria (2002). All patients received PIT sessions. The injection done once weekly for 6 weeks. They were assessed before and after the treatment sessions by the following: provocative tests (Tinel, phalen and reverse phalen), clinical assessment scale (VAS and BCTQ"SSS, FSS") and nerve conduction study. Results By the end of the treatment, All provocative tests & All assessment scores showed a highly statistical significant difference (p > 0.01). Regarding sensory examination: night parethesia, hand pain and tingling &numbness showed a highly statistical significant difference (p > 0.01). Our results as regard nerve conduction studies of DML, sensory CV and DSL —difference between median and ulnar nerves showed that there was a statistical significant difference with improvement and there was a highly statistical significant difference with improvement as regard DSL and DML-difference between median and ulnar nerves. Before treatment VAS has a positive correlation with DML (r = 0.448, P < 0.05), another significant positive correlation was found between SSS and DSI (r = 0.45 , p < 0.05), but there was a negative correlation between VAS and the following MCV (r=-0.536, p < 0.05) and SCV (r= -0.462, p < 0.05). After treatment there was a negative correlation between VAS and the following SCV (r = -0.528, p < 0.05) and MCV (r= -0.618, p- 0,01 ). Conclusion Our study revealed that PIT Of D5W is an effective treatment for patients with mild to moderate CIS. |
format |
Article in Journal/Newspaper |
author |
Elsebaie, M A Elarousi, N H Elattar, E A Mohamed, A A |
author_facet |
Elsebaie, M A Elarousi, N H Elattar, E A Mohamed, A A |
author_sort |
Elsebaie, M A |
title |
The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome |
title_short |
The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome |
title_full |
The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome |
title_fullStr |
The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome |
title_full_unstemmed |
The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome |
title_sort |
effect of perineural injection in the treatment of carpal tunnel syndrome |
publisher |
Oxford University Press (OUP) |
publishDate |
2020 |
url |
http://dx.doi.org/10.1093/qjmed/hcaa064.009 http://academic.oup.com/qjmed/article-pdf/113/Supplement_1/hcaa064.009/33164082/hcaa064.009.pdf |
genre |
DML |
genre_facet |
DML |
op_source |
QJM: An International Journal of Medicine volume 113, issue Supplement_1 ISSN 1460-2725 1460-2393 |
op_rights |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
op_doi |
https://doi.org/10.1093/qjmed/hcaa064.009 |
container_title |
QJM: An International Journal of Medicine |
container_volume |
113 |
container_issue |
Supplement_1 |
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1766397451532500992 |