Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird
Abstract Toll-like receptors (TLRs) are a crucial component of vertebrate innate immune response. Despite their importance, associations of TLR diversity with fitness-related traits have rarely been examined in wild animal populations. Here, we tested for associations of TLR polymorphism with physio...
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croxfordunivpr:10.1093/ornithology/ukab052 2023-12-10T09:54:38+01:00 Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird Podlaszczuk, Patrycja Indykiewicz, Piotr Kamiński, Maciej Minias, Piotr 2021 http://dx.doi.org/10.1093/ornithology/ukab052 https://academic.oup.com/auk/article-pdf/138/4/ukab052/41145946/ukab052.pdf en eng Oxford University Press (OUP) https://creativecommons.org/licenses/by/4.0/ Ornithology volume 138, issue 4 ISSN 0004-8038 2732-4613 Animal Science and Zoology Ecology, Evolution, Behavior and Systematics journal-article 2021 croxfordunivpr https://doi.org/10.1093/ornithology/ukab052 2023-11-10T10:02:54Z Abstract Toll-like receptors (TLRs) are a crucial component of vertebrate innate immune response. Despite their importance, associations of TLR diversity with fitness-related traits have rarely been examined in wild animal populations. Here, we tested for associations of TLR polymorphism with physiological condition in a colonial waterbird, the Black-headed Gull (Chroicocephalus ridibundus). Physiological condition and polymorphism at 4 TLR loci were assessed in 60 gulls from a breeding colony in northern Poland. We found that blood hemoglobin and plasma albumin concentrations were positively associated with TLR diversity across all genotyped loci. Plasma concentrations of albumin and triglycerides were also associated with the presence of specific TLR variants and locus-specific diversity. All significant associations between physiological condition and TLRs were primarily apparent at the level of nucleotide, rather than amino acid allelic variants. Although the exact molecular mechanisms responsible for these associations require further investigation, our study provides strong correlational support for links between TLR diversity and physiological condition in a wild avian population, and it adds to the growing, but still modest, body of evidence for the fitness-related consequences of individual TLR repertoire in wild birds. Article in Journal/Newspaper Black-headed Gull Chroicocephalus ridibundus Oxford University Press (via Crossref) Ornithology |
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Open Polar |
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Oxford University Press (via Crossref) |
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English |
topic |
Animal Science and Zoology Ecology, Evolution, Behavior and Systematics |
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Animal Science and Zoology Ecology, Evolution, Behavior and Systematics Podlaszczuk, Patrycja Indykiewicz, Piotr Kamiński, Maciej Minias, Piotr Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
topic_facet |
Animal Science and Zoology Ecology, Evolution, Behavior and Systematics |
description |
Abstract Toll-like receptors (TLRs) are a crucial component of vertebrate innate immune response. Despite their importance, associations of TLR diversity with fitness-related traits have rarely been examined in wild animal populations. Here, we tested for associations of TLR polymorphism with physiological condition in a colonial waterbird, the Black-headed Gull (Chroicocephalus ridibundus). Physiological condition and polymorphism at 4 TLR loci were assessed in 60 gulls from a breeding colony in northern Poland. We found that blood hemoglobin and plasma albumin concentrations were positively associated with TLR diversity across all genotyped loci. Plasma concentrations of albumin and triglycerides were also associated with the presence of specific TLR variants and locus-specific diversity. All significant associations between physiological condition and TLRs were primarily apparent at the level of nucleotide, rather than amino acid allelic variants. Although the exact molecular mechanisms responsible for these associations require further investigation, our study provides strong correlational support for links between TLR diversity and physiological condition in a wild avian population, and it adds to the growing, but still modest, body of evidence for the fitness-related consequences of individual TLR repertoire in wild birds. |
format |
Article in Journal/Newspaper |
author |
Podlaszczuk, Patrycja Indykiewicz, Piotr Kamiński, Maciej Minias, Piotr |
author_facet |
Podlaszczuk, Patrycja Indykiewicz, Piotr Kamiński, Maciej Minias, Piotr |
author_sort |
Podlaszczuk, Patrycja |
title |
Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
title_short |
Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
title_full |
Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
title_fullStr |
Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
title_full_unstemmed |
Physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
title_sort |
physiological condition reflects polymorphism at the toll-like receptors in a colonial waterbird |
publisher |
Oxford University Press (OUP) |
publishDate |
2021 |
url |
http://dx.doi.org/10.1093/ornithology/ukab052 https://academic.oup.com/auk/article-pdf/138/4/ukab052/41145946/ukab052.pdf |
genre |
Black-headed Gull Chroicocephalus ridibundus |
genre_facet |
Black-headed Gull Chroicocephalus ridibundus |
op_source |
Ornithology volume 138, issue 4 ISSN 0004-8038 2732-4613 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1093/ornithology/ukab052 |
container_title |
Ornithology |
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1784902157128957952 |