The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses
ABSTRACT Background The nitrogen isotope ratio (NIR) is a promising index of traditional food intake for an Alaska Native (Yup'ik) population, which can be measured in blood and hair. However, the NIR has not been calibrated to high-quality measures of Yup'ik traditional food intake. Objec...
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Online Access: | http://dx.doi.org/10.1093/jn/nxz144 http://academic.oup.com/jn/article-pdf/149/11/1960/30341852/nxz144.pdf |
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croxfordunivpr:10.1093/jn/nxz144 2023-05-15T17:05:40+02:00 The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses Choy, Kyungcheol Nash, Sarah H Hill, Courtney Bersamin, Andrea Hopkins, Scarlett E Boyer, Bert B O'Brien, Diane M National Center for Research Resources National Institute of General Medical Sciences 2019 http://dx.doi.org/10.1093/jn/nxz144 http://academic.oup.com/jn/article-pdf/149/11/1960/30341852/nxz144.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model The Journal of Nutrition volume 149, issue 11, page 1960-1966 ISSN 0022-3166 1541-6100 Nutrition and Dietetics Medicine (miscellaneous) journal-article 2019 croxfordunivpr https://doi.org/10.1093/jn/nxz144 2022-12-29T15:34:08Z ABSTRACT Background The nitrogen isotope ratio (NIR) is a promising index of traditional food intake for an Alaska Native (Yup'ik) population, which can be measured in blood and hair. However, the NIR has not been calibrated to high-quality measures of Yup'ik traditional food intake. Objectives Our primary objective was to examine associations between intakes of Yup'ik traditional food groups, including fish, marine mammals, birds, land mammals, berries, greens, and total traditional foods, and the NIR. In an exploratory analysis, we also examined whether NIR analyzed sequentially along hair could reflect dietary seasonality. Methods We recruited 68 participants from 2 Yup'ik communities in the Yukon Kuskokwim region of Southwest Alaska (49% female, aged 14–79 y). Participants completed 4 unscheduled 24-h food recalls over the period peak of RBC and hair synthesis preceding a specimen collection visit. The NIR was measured in RBCs ( n = 68), a proximal hair section (n = 58), and sequential segments of hair from individuals in the upper 2 quartiles of traditional food intake having hair >6 cm in length, plus 2 low subsistence participants for reference (n = 18). Diet–biomarker associations were assessed using Pearson's correlation and linear regression. Results Intakes of fish, marine mammals, berries, and greens were significantly associated with the NIR. The strongest dietary association was with total traditional food intake (R2 = 0.62), which indicated that each 1‰ increase in the RBC NIR corresponded to 8% of energy from traditional foods. Hair NIR appeared to fluctuate seasonally in some individuals, peaking in the summertime. Conclusions Findings support the use of the RBC and hair NIR to assess total traditional food intake in a Yup'ik population. Analyses of sequential hair NIR provided evidence of seasonality in traditional food intake, although seasonal variations were modest relative to interindividual variation. Article in Journal/Newspaper Kuskokwim Yup'ik Alaska Yukon Oxford University Press (via Crossref) Yukon The Journal of Nutrition 149 11 1960 1966 |
institution |
Open Polar |
collection |
Oxford University Press (via Crossref) |
op_collection_id |
croxfordunivpr |
language |
English |
topic |
Nutrition and Dietetics Medicine (miscellaneous) |
spellingShingle |
Nutrition and Dietetics Medicine (miscellaneous) Choy, Kyungcheol Nash, Sarah H Hill, Courtney Bersamin, Andrea Hopkins, Scarlett E Boyer, Bert B O'Brien, Diane M The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses |
topic_facet |
Nutrition and Dietetics Medicine (miscellaneous) |
description |
ABSTRACT Background The nitrogen isotope ratio (NIR) is a promising index of traditional food intake for an Alaska Native (Yup'ik) population, which can be measured in blood and hair. However, the NIR has not been calibrated to high-quality measures of Yup'ik traditional food intake. Objectives Our primary objective was to examine associations between intakes of Yup'ik traditional food groups, including fish, marine mammals, birds, land mammals, berries, greens, and total traditional foods, and the NIR. In an exploratory analysis, we also examined whether NIR analyzed sequentially along hair could reflect dietary seasonality. Methods We recruited 68 participants from 2 Yup'ik communities in the Yukon Kuskokwim region of Southwest Alaska (49% female, aged 14–79 y). Participants completed 4 unscheduled 24-h food recalls over the period peak of RBC and hair synthesis preceding a specimen collection visit. The NIR was measured in RBCs ( n = 68), a proximal hair section (n = 58), and sequential segments of hair from individuals in the upper 2 quartiles of traditional food intake having hair >6 cm in length, plus 2 low subsistence participants for reference (n = 18). Diet–biomarker associations were assessed using Pearson's correlation and linear regression. Results Intakes of fish, marine mammals, berries, and greens were significantly associated with the NIR. The strongest dietary association was with total traditional food intake (R2 = 0.62), which indicated that each 1‰ increase in the RBC NIR corresponded to 8% of energy from traditional foods. Hair NIR appeared to fluctuate seasonally in some individuals, peaking in the summertime. Conclusions Findings support the use of the RBC and hair NIR to assess total traditional food intake in a Yup'ik population. Analyses of sequential hair NIR provided evidence of seasonality in traditional food intake, although seasonal variations were modest relative to interindividual variation. |
author2 |
National Center for Research Resources National Institute of General Medical Sciences |
format |
Article in Journal/Newspaper |
author |
Choy, Kyungcheol Nash, Sarah H Hill, Courtney Bersamin, Andrea Hopkins, Scarlett E Boyer, Bert B O'Brien, Diane M |
author_facet |
Choy, Kyungcheol Nash, Sarah H Hill, Courtney Bersamin, Andrea Hopkins, Scarlett E Boyer, Bert B O'Brien, Diane M |
author_sort |
Choy, Kyungcheol |
title |
The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses |
title_short |
The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses |
title_full |
The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses |
title_fullStr |
The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses |
title_full_unstemmed |
The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses |
title_sort |
nitrogen isotope ratio is a biomarker of yup'ik traditional food intake and reflects dietary seasonality in segmental hair analyses |
publisher |
Oxford University Press (OUP) |
publishDate |
2019 |
url |
http://dx.doi.org/10.1093/jn/nxz144 http://academic.oup.com/jn/article-pdf/149/11/1960/30341852/nxz144.pdf |
geographic |
Yukon |
geographic_facet |
Yukon |
genre |
Kuskokwim Yup'ik Alaska Yukon |
genre_facet |
Kuskokwim Yup'ik Alaska Yukon |
op_source |
The Journal of Nutrition volume 149, issue 11, page 1960-1966 ISSN 0022-3166 1541-6100 |
op_rights |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
op_doi |
https://doi.org/10.1093/jn/nxz144 |
container_title |
The Journal of Nutrition |
container_volume |
149 |
container_issue |
11 |
container_start_page |
1960 |
op_container_end_page |
1966 |
_version_ |
1766060371200704512 |