Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle
Abstract Icelandic Cattle is a local dairy cattle breed in Iceland. With about 26,000 breeding females, it is by far the largest among the indigenous Nordic cattle breeds. The objective of this study was to investigate the feasibility of genomic selection in Icelandic Cattle. Pedigree-based best lin...
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Oxford University Press (OUP)
2021
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Online Access: | http://dx.doi.org/10.1093/jas/skab139 http://academic.oup.com/jas/advance-article-pdf/doi/10.1093/jas/skab139/37783565/skab139.pdf https://academic.oup.com/jas/article-pdf/99/7/skab139/42570298/skab139.pdf |
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croxfordunivpr:10.1093/jas/skab139 2023-08-15T12:41:55+02:00 Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle Gautason, Egill Sahana, Goutam Su, Guosheng Benjamínsson, Baldur Helgi Jóhannesson, Guðmundur Guldbrandtsen, Bernt 2021 http://dx.doi.org/10.1093/jas/skab139 http://academic.oup.com/jas/advance-article-pdf/doi/10.1093/jas/skab139/37783565/skab139.pdf https://academic.oup.com/jas/article-pdf/99/7/skab139/42570298/skab139.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model Journal of Animal Science volume 99, issue 7 ISSN 0021-8812 1525-3163 Genetics Animal Science and Zoology General Medicine Food Science journal-article 2021 croxfordunivpr https://doi.org/10.1093/jas/skab139 2023-07-21T11:36:08Z Abstract Icelandic Cattle is a local dairy cattle breed in Iceland. With about 26,000 breeding females, it is by far the largest among the indigenous Nordic cattle breeds. The objective of this study was to investigate the feasibility of genomic selection in Icelandic Cattle. Pedigree-based best linear unbiased prediction (PBLUP) and single-step genomic best linear unbiased prediction (ssGBLUP) were compared. Accuracy, bias, and dispersion of estimated breeding values (EBV) for milk yield (MY), fat yield (FY), protein yield (PY), and somatic cell score (SCS) were estimated in a cross validation-based design. Accuracy (r^) was estimated by the correlation between EBV and corrected phenotype in a validation set. The accuracy (r^) of predictions using ssGBLUP increased by 13, 23, 19, and 20 percentage points for MY, FY, PY, and SCS for genotyped animals, compared with PBLUP. The accuracy of nongenotyped animals was not improved for MY and PY, but increased by 0.9 and 3.5 percentage points for FY and SCS. We used the linear regression (LR) method to quantify relative improvements in accuracy, bias (Δ^), and dispersion (b^) of EBV. Using the LR method, the relative improvements in accuracy of validation from PBLUP to ssGBLUP were 43%, 60%, 50%, and 48% for genotyped animals for MY, FY, PY, and SCS. Single-step GBLUP EBV were less underestimated (Δ^), and less overdispersed (b^) than PBLUP EBV for FY and PY. Pedigree-based BLUP EBV were close to unbiased for MY and SCS. Single-step GBLUP underestimated MY EBV but overestimated SCS EBV. Based on the average accuracy of 0.45 for ssGBLUP EBV obtained in this study, selection intensities according to the breeding scheme of Icelandic Cattle, and assuming a generation interval of 2.0 yr for sires of bulls, sires of dams and dams of bulls, genetic gain in Icelandic Cattle could be increased by about 50% relative to the current breeding scheme. Article in Journal/Newspaper Iceland Oxford University Press (via Crossref) Journal of Animal Science |
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Open Polar |
collection |
Oxford University Press (via Crossref) |
op_collection_id |
croxfordunivpr |
language |
English |
topic |
Genetics Animal Science and Zoology General Medicine Food Science |
spellingShingle |
Genetics Animal Science and Zoology General Medicine Food Science Gautason, Egill Sahana, Goutam Su, Guosheng Benjamínsson, Baldur Helgi Jóhannesson, Guðmundur Guldbrandtsen, Bernt Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle |
topic_facet |
Genetics Animal Science and Zoology General Medicine Food Science |
description |
Abstract Icelandic Cattle is a local dairy cattle breed in Iceland. With about 26,000 breeding females, it is by far the largest among the indigenous Nordic cattle breeds. The objective of this study was to investigate the feasibility of genomic selection in Icelandic Cattle. Pedigree-based best linear unbiased prediction (PBLUP) and single-step genomic best linear unbiased prediction (ssGBLUP) were compared. Accuracy, bias, and dispersion of estimated breeding values (EBV) for milk yield (MY), fat yield (FY), protein yield (PY), and somatic cell score (SCS) were estimated in a cross validation-based design. Accuracy (r^) was estimated by the correlation between EBV and corrected phenotype in a validation set. The accuracy (r^) of predictions using ssGBLUP increased by 13, 23, 19, and 20 percentage points for MY, FY, PY, and SCS for genotyped animals, compared with PBLUP. The accuracy of nongenotyped animals was not improved for MY and PY, but increased by 0.9 and 3.5 percentage points for FY and SCS. We used the linear regression (LR) method to quantify relative improvements in accuracy, bias (Δ^), and dispersion (b^) of EBV. Using the LR method, the relative improvements in accuracy of validation from PBLUP to ssGBLUP were 43%, 60%, 50%, and 48% for genotyped animals for MY, FY, PY, and SCS. Single-step GBLUP EBV were less underestimated (Δ^), and less overdispersed (b^) than PBLUP EBV for FY and PY. Pedigree-based BLUP EBV were close to unbiased for MY and SCS. Single-step GBLUP underestimated MY EBV but overestimated SCS EBV. Based on the average accuracy of 0.45 for ssGBLUP EBV obtained in this study, selection intensities according to the breeding scheme of Icelandic Cattle, and assuming a generation interval of 2.0 yr for sires of bulls, sires of dams and dams of bulls, genetic gain in Icelandic Cattle could be increased by about 50% relative to the current breeding scheme. |
format |
Article in Journal/Newspaper |
author |
Gautason, Egill Sahana, Goutam Su, Guosheng Benjamínsson, Baldur Helgi Jóhannesson, Guðmundur Guldbrandtsen, Bernt |
author_facet |
Gautason, Egill Sahana, Goutam Su, Guosheng Benjamínsson, Baldur Helgi Jóhannesson, Guðmundur Guldbrandtsen, Bernt |
author_sort |
Gautason, Egill |
title |
Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle |
title_short |
Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle |
title_full |
Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle |
title_fullStr |
Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle |
title_full_unstemmed |
Short communication: investigation of the feasibility of genomic selection in Icelandic Cattle |
title_sort |
short communication: investigation of the feasibility of genomic selection in icelandic cattle |
publisher |
Oxford University Press (OUP) |
publishDate |
2021 |
url |
http://dx.doi.org/10.1093/jas/skab139 http://academic.oup.com/jas/advance-article-pdf/doi/10.1093/jas/skab139/37783565/skab139.pdf https://academic.oup.com/jas/article-pdf/99/7/skab139/42570298/skab139.pdf |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Journal of Animal Science volume 99, issue 7 ISSN 0021-8812 1525-3163 |
op_rights |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
op_doi |
https://doi.org/10.1093/jas/skab139 |
container_title |
Journal of Animal Science |
_version_ |
1774295507283214336 |