Heart disease among Greenlandic children and young adults: a nationwide cohort study
Abstract Background The incidences of heart disease (HD) and congenital heart disease (CHD) among Inuit in Greenland (GL) and Denmark (DK) are unknown. This study aims to estimate incidence rates (IRs) of HD and CHD among the young Inuit populations in Greenland and Denmark compared with rates among...
Published in: | International Journal of Epidemiology |
---|---|
Main Authors: | , , , , , , |
Other Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Oxford University Press (OUP)
2022
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1093/ije/dyac024 https://academic.oup.com/ije/article-pdf/51/5/1568/46494888/dyac024.pdf |
id |
croxfordunivpr:10.1093/ije/dyac024 |
---|---|
record_format |
openpolar |
spelling |
croxfordunivpr:10.1093/ije/dyac024 2024-06-23T07:53:09+00:00 Heart disease among Greenlandic children and young adults: a nationwide cohort study Tindborg, Marie Koch, Anders Andersson, Mikael Juul, Klaus Geisler, Uka Wilhjelm Soborg, Bolette Michelsen, Sascha Wilk Sundhedspuljen Greenland Self-Government Greenland Research Council (Nanoq–ID Dagmar Marshalls Fond 2022 http://dx.doi.org/10.1093/ije/dyac024 https://academic.oup.com/ije/article-pdf/51/5/1568/46494888/dyac024.pdf en eng Oxford University Press (OUP) https://creativecommons.org/licenses/by/4.0/ International Journal of Epidemiology volume 51, issue 5, page 1568-1580 ISSN 0300-5771 1464-3685 journal-article 2022 croxfordunivpr https://doi.org/10.1093/ije/dyac024 2024-06-11T04:21:34Z Abstract Background The incidences of heart disease (HD) and congenital heart disease (CHD) among Inuit in Greenland (GL) and Denmark (DK) are unknown. This study aims to estimate incidence rates (IRs) of HD and CHD among the young Inuit populations in Greenland and Denmark compared with rates among young non-Inuit populations in the same countries. Methods A register-based nationwide cohort including all individuals living in Greenland and Denmark from birth to age <40 years through 1989–2014 was formed. Ethnicity was considered Inuit/mixed if at least one parent was registered as being born in Greenland. Information on HD and CHD hospitalization was obtained from national inpatient registers using ICD-8 and ICD-10 codes. Results HD IR was lower among individuals living in Greenland compared with those living in Denmark, [73.35GL (95% confidence interval (CI) 68.07 to 79.03)] vs [88.07DK (95% CI 87.38 to 88.76)], whereas CHD IRs were almost similar in the two countries [IR 34.44GL (95% CI 30.89 to 38.40) vs IR 34.67DK (95% CI 34.24 to 35.10)]. Being of Inuit/mixed ethnicity was associated with an increased risk of both HD and CHD compared with non-Inuit in Greenland and Denmark [adjusted hazard ratio HD 2.07GL (95% CI 1.25 to 3.42)] and CHD [2.92GL (95% CI 1.34 to 6.38)]. Conclusion HD IR was lower in individuals living in Greenland compared with individuals living in Denmark, whereas the CHD IRs were almost the same for both countries. However, the risk of HD including CHD was higher among individuals of Inuit/mixed ethnicity compared with non-Inuit in both countries, suggesting a role of ethnicity among children and younger adults. Article in Journal/Newspaper Greenland greenlandic inuit Oxford University Press Greenland International Journal of Epidemiology |
institution |
Open Polar |
collection |
Oxford University Press |
op_collection_id |
croxfordunivpr |
language |
English |
description |
Abstract Background The incidences of heart disease (HD) and congenital heart disease (CHD) among Inuit in Greenland (GL) and Denmark (DK) are unknown. This study aims to estimate incidence rates (IRs) of HD and CHD among the young Inuit populations in Greenland and Denmark compared with rates among young non-Inuit populations in the same countries. Methods A register-based nationwide cohort including all individuals living in Greenland and Denmark from birth to age <40 years through 1989–2014 was formed. Ethnicity was considered Inuit/mixed if at least one parent was registered as being born in Greenland. Information on HD and CHD hospitalization was obtained from national inpatient registers using ICD-8 and ICD-10 codes. Results HD IR was lower among individuals living in Greenland compared with those living in Denmark, [73.35GL (95% confidence interval (CI) 68.07 to 79.03)] vs [88.07DK (95% CI 87.38 to 88.76)], whereas CHD IRs were almost similar in the two countries [IR 34.44GL (95% CI 30.89 to 38.40) vs IR 34.67DK (95% CI 34.24 to 35.10)]. Being of Inuit/mixed ethnicity was associated with an increased risk of both HD and CHD compared with non-Inuit in Greenland and Denmark [adjusted hazard ratio HD 2.07GL (95% CI 1.25 to 3.42)] and CHD [2.92GL (95% CI 1.34 to 6.38)]. Conclusion HD IR was lower in individuals living in Greenland compared with individuals living in Denmark, whereas the CHD IRs were almost the same for both countries. However, the risk of HD including CHD was higher among individuals of Inuit/mixed ethnicity compared with non-Inuit in both countries, suggesting a role of ethnicity among children and younger adults. |
author2 |
Sundhedspuljen Greenland Self-Government Greenland Research Council (Nanoq–ID Dagmar Marshalls Fond |
format |
Article in Journal/Newspaper |
author |
Tindborg, Marie Koch, Anders Andersson, Mikael Juul, Klaus Geisler, Uka Wilhjelm Soborg, Bolette Michelsen, Sascha Wilk |
spellingShingle |
Tindborg, Marie Koch, Anders Andersson, Mikael Juul, Klaus Geisler, Uka Wilhjelm Soborg, Bolette Michelsen, Sascha Wilk Heart disease among Greenlandic children and young adults: a nationwide cohort study |
author_facet |
Tindborg, Marie Koch, Anders Andersson, Mikael Juul, Klaus Geisler, Uka Wilhjelm Soborg, Bolette Michelsen, Sascha Wilk |
author_sort |
Tindborg, Marie |
title |
Heart disease among Greenlandic children and young adults: a nationwide cohort study |
title_short |
Heart disease among Greenlandic children and young adults: a nationwide cohort study |
title_full |
Heart disease among Greenlandic children and young adults: a nationwide cohort study |
title_fullStr |
Heart disease among Greenlandic children and young adults: a nationwide cohort study |
title_full_unstemmed |
Heart disease among Greenlandic children and young adults: a nationwide cohort study |
title_sort |
heart disease among greenlandic children and young adults: a nationwide cohort study |
publisher |
Oxford University Press (OUP) |
publishDate |
2022 |
url |
http://dx.doi.org/10.1093/ije/dyac024 https://academic.oup.com/ije/article-pdf/51/5/1568/46494888/dyac024.pdf |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland greenlandic inuit |
genre_facet |
Greenland greenlandic inuit |
op_source |
International Journal of Epidemiology volume 51, issue 5, page 1568-1580 ISSN 0300-5771 1464-3685 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1093/ije/dyac024 |
container_title |
International Journal of Epidemiology |
_version_ |
1802644675013640192 |