Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study
Abstract Background More information on the health-related repercussions of age at onset of adolescent drinking is needed. The aim of this study was to examine the associations between self-reported age at first drink and age at first alcohol intoxication with the risk of death by age 30. Methods Th...
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croxfordunivpr:10.1093/eurpub/ckaa134 2024-04-28T08:32:25+00:00 Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study Levola, Jonna Rose, Richard J Mustonen, Antti Sarala, Marian Miettunen, Jouko Koskela, Jari Niemelä, Anni-Emilia Niemelä, Solja Juho Vainio foundation and Päivikki and Sakari Sohlberg foundation 2020 http://dx.doi.org/10.1093/eurpub/ckaa134 http://academic.oup.com/eurpub/article-pdf/30/6/1189/34874495/ckaa134.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model European Journal of Public Health volume 30, issue 6, page 1189-1193 ISSN 1101-1262 1464-360X Public Health, Environmental and Occupational Health journal-article 2020 croxfordunivpr https://doi.org/10.1093/eurpub/ckaa134 2024-04-09T07:56:17Z Abstract Background More information on the health-related repercussions of age at onset of adolescent drinking is needed. The aim of this study was to examine the associations between self-reported age at first drink and age at first alcohol intoxication with the risk of death by age 30. Methods The sample (n = 6564; 49.1% males) included all participants of the Northern Finland Birth Cohort Study 1986 (NFBC1986) for whom the two measures of adolescent drinking were available. Self-reported age at onset of first drink and first alcohol intoxication were analyzed along with background variables and data regarding subsequent psychiatric diagnoses. Adolescents were dichotomized into those reporting age at first drink and age at first intoxication before or after age 14. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence interval (95% CI) for death by age 30. Results By the age of 30, 0.7% (n = 47) of all 6564 participants were deceased. In the multivariable models, male gender and a history of illicit substance use in adolescence were associated with both all-cause mortality and mortality due to accidents or suicide. After controlling for confounding variables, age at first alcohol intoxication was associated with all-cause mortality (HR 2.33; 95% CI 1.04–5.20) as well as death due to accidents or suicide (HR 2.99; 95% CI 1.11–8.05). Conclusions Earlier age at first intoxication carries long-term repercussions with respect to premature loss of life. Efforts should be made targeting the prolongation of initiating binge drinking in adolescence to diminish this mortality risk. Article in Journal/Newspaper Northern Finland Oxford University Press European Journal of Public Health 30 6 1189 1193 |
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Oxford University Press |
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croxfordunivpr |
language |
English |
topic |
Public Health, Environmental and Occupational Health |
spellingShingle |
Public Health, Environmental and Occupational Health Levola, Jonna Rose, Richard J Mustonen, Antti Sarala, Marian Miettunen, Jouko Koskela, Jari Niemelä, Anni-Emilia Niemelä, Solja Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
topic_facet |
Public Health, Environmental and Occupational Health |
description |
Abstract Background More information on the health-related repercussions of age at onset of adolescent drinking is needed. The aim of this study was to examine the associations between self-reported age at first drink and age at first alcohol intoxication with the risk of death by age 30. Methods The sample (n = 6564; 49.1% males) included all participants of the Northern Finland Birth Cohort Study 1986 (NFBC1986) for whom the two measures of adolescent drinking were available. Self-reported age at onset of first drink and first alcohol intoxication were analyzed along with background variables and data regarding subsequent psychiatric diagnoses. Adolescents were dichotomized into those reporting age at first drink and age at first intoxication before or after age 14. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence interval (95% CI) for death by age 30. Results By the age of 30, 0.7% (n = 47) of all 6564 participants were deceased. In the multivariable models, male gender and a history of illicit substance use in adolescence were associated with both all-cause mortality and mortality due to accidents or suicide. After controlling for confounding variables, age at first alcohol intoxication was associated with all-cause mortality (HR 2.33; 95% CI 1.04–5.20) as well as death due to accidents or suicide (HR 2.99; 95% CI 1.11–8.05). Conclusions Earlier age at first intoxication carries long-term repercussions with respect to premature loss of life. Efforts should be made targeting the prolongation of initiating binge drinking in adolescence to diminish this mortality risk. |
author2 |
Juho Vainio foundation and Päivikki and Sakari Sohlberg foundation |
format |
Article in Journal/Newspaper |
author |
Levola, Jonna Rose, Richard J Mustonen, Antti Sarala, Marian Miettunen, Jouko Koskela, Jari Niemelä, Anni-Emilia Niemelä, Solja |
author_facet |
Levola, Jonna Rose, Richard J Mustonen, Antti Sarala, Marian Miettunen, Jouko Koskela, Jari Niemelä, Anni-Emilia Niemelä, Solja |
author_sort |
Levola, Jonna |
title |
Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
title_short |
Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
title_full |
Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
title_fullStr |
Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
title_full_unstemmed |
Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
title_sort |
association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study |
publisher |
Oxford University Press (OUP) |
publishDate |
2020 |
url |
http://dx.doi.org/10.1093/eurpub/ckaa134 http://academic.oup.com/eurpub/article-pdf/30/6/1189/34874495/ckaa134.pdf |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
European Journal of Public Health volume 30, issue 6, page 1189-1193 ISSN 1101-1262 1464-360X |
op_rights |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
op_doi |
https://doi.org/10.1093/eurpub/ckaa134 |
container_title |
European Journal of Public Health |
container_volume |
30 |
container_issue |
6 |
container_start_page |
1189 |
op_container_end_page |
1193 |
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1797589622401794048 |