P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies
Abstract Funding Acknowledgements none Introduction The second-generation CB (CB2, Arctic Front Advance, Medtronic Inc., Minneapolis, USA) has demonstrated high procedural success rates, relatively short procedure times, high durability of PVI and convincing long-term clinical success rates. Neverth...
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2020
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Online Access: | http://dx.doi.org/10.1093/europace/euaa162.306 http://academic.oup.com/europace/article-pdf/22/Supplement_1/euaa162.306/33547581/euaa162.306.pdf |
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croxfordunivpr:10.1093/europace/euaa162.306 2023-10-01T03:54:18+02:00 P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies Heeger, C H Rexha, E R Maack, S M Rottner, L Fink, T Mathew, S M Maurer, T M Lemes, C L Rillig, A R Wohlmuth, P W Reissmann, B R Tilz, R R Ouyang, F O Kuck, K H K Metzner, A M 2020 http://dx.doi.org/10.1093/europace/euaa162.306 http://academic.oup.com/europace/article-pdf/22/Supplement_1/euaa162.306/33547581/euaa162.306.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model EP Europace volume 22, issue Supplement_1 ISSN 1099-5129 1532-2092 Physiology (medical) Cardiology and Cardiovascular Medicine journal-article 2020 croxfordunivpr https://doi.org/10.1093/europace/euaa162.306 2023-09-08T10:50:04Z Abstract Funding Acknowledgements none Introduction The second-generation CB (CB2, Arctic Front Advance, Medtronic Inc., Minneapolis, USA) has demonstrated high procedural success rates, relatively short procedure times, high durability of PVI and convincing long-term clinical success rates. Nevertheless, data on the impact of different ablations protocols on durability after CB2 based PVI is limited. Purpose We aimed at comparing durability of pulmonary vein isolation (PVI) following three different ablation strategies utilizing the second-generation cryoballoon (CB2) in patients with recurrence of atrial fibrillation (AF) or atrial tachycardia (AT) undergoing repeat procedures. Methods In 192 patients a total of 751 PVs were identified. All PVs (751/751, 100%) were successfully isolated during index PVI. Thirty-one out of 192 (16%) patients were treated with a bonus-freeze protocol (group 1), 67/192 (35%) patients with a no bonus-freeze protocol (group 2), and 94/192 (49%) patients with a "time-to-effect"-guided ablation protocol without bonus freezes (group 3). Results Persistent PVI was documented in 419/751 (55.8%) PVs, and in 41/192 (21%) patients all PVs were persistently isolated. The number of patients with all PVs being persistently isolated was not significant between the groups (p = 0.594). The total rate of PV reconnection was not significantly different between the three groups (p = 0.134) and the comparison of individual PVs revealed also no differences for different ablation protocols (p-values for RSPV: 0.424, RIPV: 0.541, LSPV: 0.788, LIPV: 0.346, LCPV: 0.865). The procedure times were significantly reduced in non-bonus freeze ablation protocols and/or when applying individualized application times (group 1: 123.4 ± 31.5min, group 2: 112.9 ± 39.8 min, group 3: 86.67 ± 28.4 min, p <0.001). Conclusions A considerably high rate of persistent PVI was demonstrated in patients after index CB2-based PVI. No differences for durable PVI were detected for different ablation protocols. Therefore, ... Article in Journal/Newspaper Arctic Oxford University Press (via Crossref) Arctic EP Europace 22 Supplement_1 |
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Oxford University Press (via Crossref) |
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croxfordunivpr |
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English |
topic |
Physiology (medical) Cardiology and Cardiovascular Medicine |
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Physiology (medical) Cardiology and Cardiovascular Medicine Heeger, C H Rexha, E R Maack, S M Rottner, L Fink, T Mathew, S M Maurer, T M Lemes, C L Rillig, A R Wohlmuth, P W Reissmann, B R Tilz, R R Ouyang, F O Kuck, K H K Metzner, A M P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies |
topic_facet |
Physiology (medical) Cardiology and Cardiovascular Medicine |
description |
Abstract Funding Acknowledgements none Introduction The second-generation CB (CB2, Arctic Front Advance, Medtronic Inc., Minneapolis, USA) has demonstrated high procedural success rates, relatively short procedure times, high durability of PVI and convincing long-term clinical success rates. Nevertheless, data on the impact of different ablations protocols on durability after CB2 based PVI is limited. Purpose We aimed at comparing durability of pulmonary vein isolation (PVI) following three different ablation strategies utilizing the second-generation cryoballoon (CB2) in patients with recurrence of atrial fibrillation (AF) or atrial tachycardia (AT) undergoing repeat procedures. Methods In 192 patients a total of 751 PVs were identified. All PVs (751/751, 100%) were successfully isolated during index PVI. Thirty-one out of 192 (16%) patients were treated with a bonus-freeze protocol (group 1), 67/192 (35%) patients with a no bonus-freeze protocol (group 2), and 94/192 (49%) patients with a "time-to-effect"-guided ablation protocol without bonus freezes (group 3). Results Persistent PVI was documented in 419/751 (55.8%) PVs, and in 41/192 (21%) patients all PVs were persistently isolated. The number of patients with all PVs being persistently isolated was not significant between the groups (p = 0.594). The total rate of PV reconnection was not significantly different between the three groups (p = 0.134) and the comparison of individual PVs revealed also no differences for different ablation protocols (p-values for RSPV: 0.424, RIPV: 0.541, LSPV: 0.788, LIPV: 0.346, LCPV: 0.865). The procedure times were significantly reduced in non-bonus freeze ablation protocols and/or when applying individualized application times (group 1: 123.4 ± 31.5min, group 2: 112.9 ± 39.8 min, group 3: 86.67 ± 28.4 min, p <0.001). Conclusions A considerably high rate of persistent PVI was demonstrated in patients after index CB2-based PVI. No differences for durable PVI were detected for different ablation protocols. Therefore, ... |
format |
Article in Journal/Newspaper |
author |
Heeger, C H Rexha, E R Maack, S M Rottner, L Fink, T Mathew, S M Maurer, T M Lemes, C L Rillig, A R Wohlmuth, P W Reissmann, B R Tilz, R R Ouyang, F O Kuck, K H K Metzner, A M |
author_facet |
Heeger, C H Rexha, E R Maack, S M Rottner, L Fink, T Mathew, S M Maurer, T M Lemes, C L Rillig, A R Wohlmuth, P W Reissmann, B R Tilz, R R Ouyang, F O Kuck, K H K Metzner, A M |
author_sort |
Heeger, C H |
title |
P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies |
title_short |
P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies |
title_full |
P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies |
title_fullStr |
P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies |
title_full_unstemmed |
P1025Incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: Impact of different ablation strategies |
title_sort |
p1025incidence and characteristics of pulmonary vein reconduction after second-generation cryoballoon-based pulmonary vein isolation: impact of different ablation strategies |
publisher |
Oxford University Press (OUP) |
publishDate |
2020 |
url |
http://dx.doi.org/10.1093/europace/euaa162.306 http://academic.oup.com/europace/article-pdf/22/Supplement_1/euaa162.306/33547581/euaa162.306.pdf |
geographic |
Arctic |
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Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
EP Europace volume 22, issue Supplement_1 ISSN 1099-5129 1532-2092 |
op_rights |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
op_doi |
https://doi.org/10.1093/europace/euaa162.306 |
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EP Europace |
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22 |
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Supplement_1 |
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