Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016
Abstract Aims To explore sex-specific time trends in atrial fibrillation (AF) incidence and to estimate the impact of changes in risk factor levels using individual participant-level data from the population-based Tromsø Study 1994–2016. Methods and results A total of 14 818 women and 13 225 men age...
Published in: | European Journal of Preventive Cardiology |
---|---|
Main Authors: | , , , , , , , , , , , |
Other Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Oxford University Press (OUP)
2022
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1093/eurjpc/zwac234 https://academic.oup.com/eurjpc/advance-article-pdf/doi/10.1093/eurjpc/zwac234/46679598/zwac234.pdf https://academic.oup.com/eurjpc/article-pdf/30/1/72/48617492/zwac234.pdf |
id |
croxfordunivpr:10.1093/eurjpc/zwac234 |
---|---|
record_format |
openpolar |
spelling |
croxfordunivpr:10.1093/eurjpc/zwac234 2024-09-15T18:39:21+00:00 Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 Sharashova, Ekaterina Gerdts, Eva Ball, Jocasta Espnes, Hilde Jacobsen, Bjarne K Kildal, Simon Mathiesen, Ellisiv B Njølstad, Inger Rosengren, Annika Schirmer, Henrik Wilsgaard, Tom Løchen, Maja-Lisa Helse Nord RHF Swedish Research Council Swedish Heart Lung Foundation Specialist Health Services Northern Norway Regional Health Authorities Australia/National Heart Foundation 2022 http://dx.doi.org/10.1093/eurjpc/zwac234 https://academic.oup.com/eurjpc/advance-article-pdf/doi/10.1093/eurjpc/zwac234/46679598/zwac234.pdf https://academic.oup.com/eurjpc/article-pdf/30/1/72/48617492/zwac234.pdf en eng Oxford University Press (OUP) https://creativecommons.org/licenses/by-nc/4.0/ European Journal of Preventive Cardiology volume 30, issue 1, page 72-81 ISSN 2047-4873 2047-4881 journal-article 2022 croxfordunivpr https://doi.org/10.1093/eurjpc/zwac234 2024-08-27T04:17:19Z Abstract Aims To explore sex-specific time trends in atrial fibrillation (AF) incidence and to estimate the impact of changes in risk factor levels using individual participant-level data from the population-based Tromsø Study 1994–2016. Methods and results A total of 14 818 women and 13 225 men aged 25 years or older without AF were enrolled in the Tromsø Study between 1994 and 2008 and followed up for incident AF throughout 2016. Poisson regression was used for statistical analyses. During follow-up, age-adjusted AF incidence rates in women decreased from 1.19 to 0.71 per 1000 person-years. In men, AF incidence increased from 1.18 to 2.82 per 1000 person-years in 2004, and then declined to 1.94 per 1000 person-years in 2016. Changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP), body mass index (BMI), physical activity, smoking and alcohol consumption together accounted for 10.9% [95% confidence interval (CI): −2.4 to 28.6] of the AF incidence decline in women and for 44.7% (95% CI: 19.2; 100.0) of the AF incidence increase in men. Reduction in SBP and DBP had the largest contribution to the decrease in AF incidence in women. Increase in BMI had the largest contribution to the increase in AF incidence in men. Conclusion In the population-based Tromsø Study 1994–2016, AF incidence decreased in women and increased following a reverse U-shape in men. Individual changes in SBP and DBP in women and individual changes in BMI in men were the most important risk factors contributing to the AF incidence trends. Article in Journal/Newspaper Tromsø Oxford University Press European Journal of Preventive Cardiology |
institution |
Open Polar |
collection |
Oxford University Press |
op_collection_id |
croxfordunivpr |
language |
English |
description |
Abstract Aims To explore sex-specific time trends in atrial fibrillation (AF) incidence and to estimate the impact of changes in risk factor levels using individual participant-level data from the population-based Tromsø Study 1994–2016. Methods and results A total of 14 818 women and 13 225 men aged 25 years or older without AF were enrolled in the Tromsø Study between 1994 and 2008 and followed up for incident AF throughout 2016. Poisson regression was used for statistical analyses. During follow-up, age-adjusted AF incidence rates in women decreased from 1.19 to 0.71 per 1000 person-years. In men, AF incidence increased from 1.18 to 2.82 per 1000 person-years in 2004, and then declined to 1.94 per 1000 person-years in 2016. Changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP), body mass index (BMI), physical activity, smoking and alcohol consumption together accounted for 10.9% [95% confidence interval (CI): −2.4 to 28.6] of the AF incidence decline in women and for 44.7% (95% CI: 19.2; 100.0) of the AF incidence increase in men. Reduction in SBP and DBP had the largest contribution to the decrease in AF incidence in women. Increase in BMI had the largest contribution to the increase in AF incidence in men. Conclusion In the population-based Tromsø Study 1994–2016, AF incidence decreased in women and increased following a reverse U-shape in men. Individual changes in SBP and DBP in women and individual changes in BMI in men were the most important risk factors contributing to the AF incidence trends. |
author2 |
Helse Nord RHF Swedish Research Council Swedish Heart Lung Foundation Specialist Health Services Northern Norway Regional Health Authorities Australia/National Heart Foundation |
format |
Article in Journal/Newspaper |
author |
Sharashova, Ekaterina Gerdts, Eva Ball, Jocasta Espnes, Hilde Jacobsen, Bjarne K Kildal, Simon Mathiesen, Ellisiv B Njølstad, Inger Rosengren, Annika Schirmer, Henrik Wilsgaard, Tom Løchen, Maja-Lisa |
spellingShingle |
Sharashova, Ekaterina Gerdts, Eva Ball, Jocasta Espnes, Hilde Jacobsen, Bjarne K Kildal, Simon Mathiesen, Ellisiv B Njølstad, Inger Rosengren, Annika Schirmer, Henrik Wilsgaard, Tom Løchen, Maja-Lisa Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 |
author_facet |
Sharashova, Ekaterina Gerdts, Eva Ball, Jocasta Espnes, Hilde Jacobsen, Bjarne K Kildal, Simon Mathiesen, Ellisiv B Njølstad, Inger Rosengren, Annika Schirmer, Henrik Wilsgaard, Tom Løchen, Maja-Lisa |
author_sort |
Sharashova, Ekaterina |
title |
Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 |
title_short |
Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 |
title_full |
Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 |
title_fullStr |
Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 |
title_full_unstemmed |
Sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016 |
title_sort |
sex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the tromsø study 1994–2016 |
publisher |
Oxford University Press (OUP) |
publishDate |
2022 |
url |
http://dx.doi.org/10.1093/eurjpc/zwac234 https://academic.oup.com/eurjpc/advance-article-pdf/doi/10.1093/eurjpc/zwac234/46679598/zwac234.pdf https://academic.oup.com/eurjpc/article-pdf/30/1/72/48617492/zwac234.pdf |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
European Journal of Preventive Cardiology volume 30, issue 1, page 72-81 ISSN 2047-4873 2047-4881 |
op_rights |
https://creativecommons.org/licenses/by-nc/4.0/ |
op_doi |
https://doi.org/10.1093/eurjpc/zwac234 |
container_title |
European Journal of Preventive Cardiology |
_version_ |
1810483745112719360 |