Proportion of ischemic and nonischemic sudden cardiac death by age and sex
Abstract Background Among women the incidence of sudden cardiac death (SCD) is significant, but lower than in men. During the last decades the proportion of nonischemic SCD seems to have increased in both sexes. Coronary artery disease (CAD) have changed to be sickness of elderly women rather than m...
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croxfordunivpr:10.1093/eurheartj/ehad655.634 2023-12-31T10:21:14+01:00 Proportion of ischemic and nonischemic sudden cardiac death by age and sex Eskuri, M A E Holmstrom, L Vahatalo, J Kentta, T V Tikkanen, J Pakanen, L Kortelainen, M L Perkiomaki, J Huikuri, H V Junttila, M J 2023 http://dx.doi.org/10.1093/eurheartj/ehad655.634 https://academic.oup.com/eurheartj/article-pdf/44/Supplement_2/ehad655.634/53602625/ehad655.634.pdf en eng Oxford University Press (OUP) https://academic.oup.com/pages/standard-publication-reuse-rights European Heart Journal volume 44, issue Supplement_2 ISSN 0195-668X 1522-9645 Cardiology and Cardiovascular Medicine journal-article 2023 croxfordunivpr https://doi.org/10.1093/eurheartj/ehad655.634 2023-12-06T08:59:26Z Abstract Background Among women the incidence of sudden cardiac death (SCD) is significant, but lower than in men. During the last decades the proportion of nonischemic SCD seems to have increased in both sexes. Coronary artery disease (CAD) have changed to be sickness of elderly women rather than middle-aged men as in women the prevalence and incidence of CAD starts to increase after the menopause. Purpose The aim of this study was to illustrate how the amount and the proportions of ischemic and nonischemic SCD vary between women and men in different age groups. Methods The Fingesture study has systematically collected clinical and autopsy data from SCD victims in Northern Finland between 1998 and 2017. The cohort consists of 5,869 SCD victims. Results Approximately one fifth of the SCD victims were women (21.1%; P<0.001). Three out of four SCDs were ischemic (74.8%; P<0.001) and majority of the ischemic SCD victims were men (79.8%; P=0.005). The mean age of female victims was 70.1±13.1 years and 63.5±11.8 years among male victims (P<0.001). Amongst women one SCD out of 15 occurred to the subject under 50 years of age (6.7%; P<0.001) whereas in men one SCD victim out of nine was under 50 years old (11.4%; P<0.001). A nonischemic SCD was observed in 350 women and in 1,127 men (P<0.001). The proportion of nonischemic death was higher among women than in men in every age group from under 30 years of age to subjects of 84 years old studied in five year periods (Figure 1). Only age group of 65-69 years in women and 60-64 years in men were not statistically significant, otherwise all the P-values were ≤0.003. The difference in proportion of ischemic and non-ischemic SCD was the smallest among subjects of 40-49 years of age amongst the proportion of ischemic SCD increased rapidly both in women and in men as the prevalence of non-ischemic SCD started to decrease (Figure 1). Amongst SCD victims aged 40-44 years 47.9% of the deaths of men (P<0.001) and 41.7% of the deaths ... Article in Journal/Newspaper Northern Finland Oxford University Press (via Crossref) European Heart Journal 44 Supplement_2 |
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Open Polar |
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Oxford University Press (via Crossref) |
op_collection_id |
croxfordunivpr |
language |
English |
topic |
Cardiology and Cardiovascular Medicine |
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Cardiology and Cardiovascular Medicine Eskuri, M A E Holmstrom, L Vahatalo, J Kentta, T V Tikkanen, J Pakanen, L Kortelainen, M L Perkiomaki, J Huikuri, H V Junttila, M J Proportion of ischemic and nonischemic sudden cardiac death by age and sex |
topic_facet |
Cardiology and Cardiovascular Medicine |
description |
Abstract Background Among women the incidence of sudden cardiac death (SCD) is significant, but lower than in men. During the last decades the proportion of nonischemic SCD seems to have increased in both sexes. Coronary artery disease (CAD) have changed to be sickness of elderly women rather than middle-aged men as in women the prevalence and incidence of CAD starts to increase after the menopause. Purpose The aim of this study was to illustrate how the amount and the proportions of ischemic and nonischemic SCD vary between women and men in different age groups. Methods The Fingesture study has systematically collected clinical and autopsy data from SCD victims in Northern Finland between 1998 and 2017. The cohort consists of 5,869 SCD victims. Results Approximately one fifth of the SCD victims were women (21.1%; P<0.001). Three out of four SCDs were ischemic (74.8%; P<0.001) and majority of the ischemic SCD victims were men (79.8%; P=0.005). The mean age of female victims was 70.1±13.1 years and 63.5±11.8 years among male victims (P<0.001). Amongst women one SCD out of 15 occurred to the subject under 50 years of age (6.7%; P<0.001) whereas in men one SCD victim out of nine was under 50 years old (11.4%; P<0.001). A nonischemic SCD was observed in 350 women and in 1,127 men (P<0.001). The proportion of nonischemic death was higher among women than in men in every age group from under 30 years of age to subjects of 84 years old studied in five year periods (Figure 1). Only age group of 65-69 years in women and 60-64 years in men were not statistically significant, otherwise all the P-values were ≤0.003. The difference in proportion of ischemic and non-ischemic SCD was the smallest among subjects of 40-49 years of age amongst the proportion of ischemic SCD increased rapidly both in women and in men as the prevalence of non-ischemic SCD started to decrease (Figure 1). Amongst SCD victims aged 40-44 years 47.9% of the deaths of men (P<0.001) and 41.7% of the deaths ... |
format |
Article in Journal/Newspaper |
author |
Eskuri, M A E Holmstrom, L Vahatalo, J Kentta, T V Tikkanen, J Pakanen, L Kortelainen, M L Perkiomaki, J Huikuri, H V Junttila, M J |
author_facet |
Eskuri, M A E Holmstrom, L Vahatalo, J Kentta, T V Tikkanen, J Pakanen, L Kortelainen, M L Perkiomaki, J Huikuri, H V Junttila, M J |
author_sort |
Eskuri, M A E |
title |
Proportion of ischemic and nonischemic sudden cardiac death by age and sex |
title_short |
Proportion of ischemic and nonischemic sudden cardiac death by age and sex |
title_full |
Proportion of ischemic and nonischemic sudden cardiac death by age and sex |
title_fullStr |
Proportion of ischemic and nonischemic sudden cardiac death by age and sex |
title_full_unstemmed |
Proportion of ischemic and nonischemic sudden cardiac death by age and sex |
title_sort |
proportion of ischemic and nonischemic sudden cardiac death by age and sex |
publisher |
Oxford University Press (OUP) |
publishDate |
2023 |
url |
http://dx.doi.org/10.1093/eurheartj/ehad655.634 https://academic.oup.com/eurheartj/article-pdf/44/Supplement_2/ehad655.634/53602625/ehad655.634.pdf |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
European Heart Journal volume 44, issue Supplement_2 ISSN 0195-668X 1522-9645 |
op_rights |
https://academic.oup.com/pages/standard-publication-reuse-rights |
op_doi |
https://doi.org/10.1093/eurheartj/ehad655.634 |
container_title |
European Heart Journal |
container_volume |
44 |
container_issue |
Supplement_2 |
_version_ |
1786831927621189632 |