Multi-species transcriptomic data analysis reveal three candidate genes, responsible for the transition from compensated left ventricle hypertrophy to heart failure

• Published in: European Heart Journal
• Main Authors: Abreu, M, Ferreira, C, Baptista, R
• Format: Article in Journal/Newspaper
• Language: English
• Published: Oxford University Press (OUP) 2021
• Subjects: Cardiology and Cardiovascular Medicine; Mek; Tac; Canis lupus
• Online Access: http://dx.doi.org/10.1093/eurheartj/ehab724.3292; https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.3292/41056781/ehab724.3292.pdf

Abstract Introduction Heart failure (HF) is the common final event for a wide spectrum of compensated left ventricle hypertrophy (LVH), including hypertrophic cardiomyopathy, hypertension, aortic stenosis and aortic coarctation. Despite its importance, the transition from hypertrophy to HF in humans...