NARWHAL, a primary analysis pipeline for NGS data

Abstract Summary: The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open-source aligners and automated quality assessment. The entire pipeline can be run using only one si...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Brouwer, R. W. W., van den Hout, M. C. G. N., Grosveld, F. G., van IJcken, W. F. J.
Format: Article in Journal/Newspaper
Language:English
Published: Oxford University Press (OUP) 2011
Subjects:
narwhal*
Online Access:http://dx.doi.org/10.1093/bioinformatics/btr613
https://academic.oup.com/bioinformatics/article-pdf/28/2/284/48870270/bioinformatics_28_2_284.pdf
Description
Summary:Abstract Summary: The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open-source aligners and automated quality assessment. The entire pipeline can be run using only one simple sample-sheet for diverse sequencing applications. NARWHAL creates a sample-oriented data structure and outperforms existing tools in speed. Availability: https://trac.nbic.nl/narwhal/ Contact: w.vanijcken@erasmusmc.nl Supplementary information: Supplementary data are available at Bioinformatics online.

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