Biosynthetic potential of uncultured Antarctic soil bacteria revealed through long-read metagenomic sequencing

• Published in: The ISME Journal
• Main Authors: Waschulin, Valentin, Borsetto, Chiara, James, Robert, Newsham, Kevin K, Donadio, Stefano, Corre, Christophe, Wellington, Elizabeth
• Other Authors: EC | Horizon 2020 Framework Programme, RCUK | Natural Environment Research Council
• Format: Article in Journal/Newspaper
• Language: English
• Published: Oxford University Press (OUP) 2021
• Subjects: Antarc*; Antarctic; Antarctica
• Online Access: http://dx.doi.org/10.1038/s41396-021-01052-3; https://www.nature.com/articles/s41396-021-01052-3.pdf; https://www.nature.com/articles/s41396-021-01052-3; https://academic.oup.com/ismej/article-pdf/16/1/101/55309506/41396_2021_article_1052.pdf

Abstract The growing problem of antibiotic resistance has led to the exploration of uncultured bacteria as potential sources of new antimicrobials. PCR amplicon analyses and short-read sequencing studies of samples from different environments have reported evidence of high biosynthetic gene cluster...