Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation
Abstract Despite knowledge that viruses are abundant in natural ecosystems, there is limited understanding of which viruses infect which hosts, and how both hosts and viruses respond to those interactions—interactions that ultimately shape community structure and dynamics. In Deep Lake, Antarctica,...
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Oxford University Press (OUP)
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croxfordunivpr:10.1038/ismej.2015.110 2024-04-07T07:47:29+00:00 Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation Tschitschko, Bernhard Williams, Timothy J Allen, Michelle A Páez-Espino, David Kyrpides, Nikos Zhong, Ling Raftery, Mark J Cavicchioli, Ricardo 2015 http://dx.doi.org/10.1038/ismej.2015.110 https://www.nature.com/articles/ismej2015110.pdf https://www.nature.com/articles/ismej2015110 https://academic.oup.com/ismej/article-pdf/9/9/2094/56371806/41396_2015_article_bfismej2015110.pdf en eng Oxford University Press (OUP) https://academic.oup.com/pages/standard-publication-reuse-rights https://www.springer.com/tdm https://www.springer.com/tdm The ISME Journal volume 9, issue 9, page 2094-2107 ISSN 1751-7362 1751-7370 Ecology, Evolution, Behavior and Systematics Microbiology journal-article 2015 croxfordunivpr https://doi.org/10.1038/ismej.2015.110 2024-03-08T03:06:44Z Abstract Despite knowledge that viruses are abundant in natural ecosystems, there is limited understanding of which viruses infect which hosts, and how both hosts and viruses respond to those interactions—interactions that ultimately shape community structure and dynamics. In Deep Lake, Antarctica, intergenera gene exchange occurs rampantly within the low complexity, haloarchaea-dominated community, strongly balanced by distinctions in niche adaptation which maintain sympatric speciation. By performing metaproteomics for the first time on haloarchaea, genomic variation of S-layer, archaella and other cell surface proteins was linked to mechanisms of infection evasion. CRISPR defense systems were found to be active, with haloarchaea responding to at least eight distinct types of viruses, including those infecting between genera. The role of BREX systems in defending against viruses was also examined. Although evasion and defense were evident, both hosts and viruses also may benefit from viruses carrying and expressing host genes, thereby potentially enhancing genetic variation and phenotypic differences within populations. The data point to a complex inter-play leading to a dynamic optimization of host–virus interactions. This comprehensive overview was achieved only through the integration of results from metaproteomics, genomics and metagenomics. Article in Journal/Newspaper Antarc* Antarctic Antarctica Oxford University Press Antarctic The ISME Journal 9 9 2094 2107 |
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Open Polar |
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Oxford University Press |
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croxfordunivpr |
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English |
topic |
Ecology, Evolution, Behavior and Systematics Microbiology |
spellingShingle |
Ecology, Evolution, Behavior and Systematics Microbiology Tschitschko, Bernhard Williams, Timothy J Allen, Michelle A Páez-Espino, David Kyrpides, Nikos Zhong, Ling Raftery, Mark J Cavicchioli, Ricardo Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
topic_facet |
Ecology, Evolution, Behavior and Systematics Microbiology |
description |
Abstract Despite knowledge that viruses are abundant in natural ecosystems, there is limited understanding of which viruses infect which hosts, and how both hosts and viruses respond to those interactions—interactions that ultimately shape community structure and dynamics. In Deep Lake, Antarctica, intergenera gene exchange occurs rampantly within the low complexity, haloarchaea-dominated community, strongly balanced by distinctions in niche adaptation which maintain sympatric speciation. By performing metaproteomics for the first time on haloarchaea, genomic variation of S-layer, archaella and other cell surface proteins was linked to mechanisms of infection evasion. CRISPR defense systems were found to be active, with haloarchaea responding to at least eight distinct types of viruses, including those infecting between genera. The role of BREX systems in defending against viruses was also examined. Although evasion and defense were evident, both hosts and viruses also may benefit from viruses carrying and expressing host genes, thereby potentially enhancing genetic variation and phenotypic differences within populations. The data point to a complex inter-play leading to a dynamic optimization of host–virus interactions. This comprehensive overview was achieved only through the integration of results from metaproteomics, genomics and metagenomics. |
format |
Article in Journal/Newspaper |
author |
Tschitschko, Bernhard Williams, Timothy J Allen, Michelle A Páez-Espino, David Kyrpides, Nikos Zhong, Ling Raftery, Mark J Cavicchioli, Ricardo |
author_facet |
Tschitschko, Bernhard Williams, Timothy J Allen, Michelle A Páez-Espino, David Kyrpides, Nikos Zhong, Ling Raftery, Mark J Cavicchioli, Ricardo |
author_sort |
Tschitschko, Bernhard |
title |
Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
title_short |
Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
title_full |
Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
title_fullStr |
Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
title_full_unstemmed |
Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
title_sort |
antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation |
publisher |
Oxford University Press (OUP) |
publishDate |
2015 |
url |
http://dx.doi.org/10.1038/ismej.2015.110 https://www.nature.com/articles/ismej2015110.pdf https://www.nature.com/articles/ismej2015110 https://academic.oup.com/ismej/article-pdf/9/9/2094/56371806/41396_2015_article_bfismej2015110.pdf |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Antarctica |
genre_facet |
Antarc* Antarctic Antarctica |
op_source |
The ISME Journal volume 9, issue 9, page 2094-2107 ISSN 1751-7362 1751-7370 |
op_rights |
https://academic.oup.com/pages/standard-publication-reuse-rights https://www.springer.com/tdm https://www.springer.com/tdm |
op_doi |
https://doi.org/10.1038/ismej.2015.110 |
container_title |
The ISME Journal |
container_volume |
9 |
container_issue |
9 |
container_start_page |
2094 |
op_container_end_page |
2107 |
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1795674612636319744 |