Isolation and confinement as a model for spaceflight Immune changes
Abstract The immune system of astronauts is disturbed during and after spaceflight. This situation may result from stressors encountered during the flight (microgravity, radiation, psychological stress, or confinement) or from physiological changes (demineralization or fluid shift). Therefore, groun...
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Oxford University Press (OUP)
1993
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croxfordunivpr:10.1002/jlb.54.3.209 2024-09-15T17:45:32+00:00 Isolation and confinement as a model for spaceflight Immune changes Schmitt, Didier A Schaffar, Laurence 1993 http://dx.doi.org/10.1002/jlb.54.3.209 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjlb.54.3.209 https://academic.oup.com/jleukbio/article-pdf/54/3/209/49769374/jlb0209.pdf en eng Oxford University Press (OUP) https://academic.oup.com/pages/standard-publication-reuse-rights Journal of Leukocyte Biology volume 54, issue 3, page 209-213 ISSN 0741-5400 1938-3673 journal-article 1993 croxfordunivpr https://doi.org/10.1002/jlb.54.3.209 2024-07-22T04:24:08Z Abstract The immune system of astronauts is disturbed during and after spaceflight. This situation may result from stressors encountered during the flight (microgravity, radiation, psychological stress, or confinement) or from physiological changes (demineralization or fluid shift). Therefore, ground-based investigations should be designed to determine the effects of these factors on the immune system. Very little is known about the influence of confinement or isolation on immune reactions. However, interesting data exist from experiments with animals and humans under different conditions (submarines, antarctic expeditions, single-person cave isolation, and underwater diving). The question remains as to whether these results can be extrapolated to spaceflight. Therefore, investigations of humans under isolation conditions analogous to space missions have been performed by Russian and, more recently, European investigators. Such investigations are important for understanding the physiological and psychological disturbances that occur during long periods of confinement, especially when future lunar and martian missions are considered. Article in Journal/Newspaper Antarc* Antarctic Oxford University Press Journal of Leukocyte Biology 54 3 209 213 |
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Oxford University Press |
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croxfordunivpr |
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description |
Abstract The immune system of astronauts is disturbed during and after spaceflight. This situation may result from stressors encountered during the flight (microgravity, radiation, psychological stress, or confinement) or from physiological changes (demineralization or fluid shift). Therefore, ground-based investigations should be designed to determine the effects of these factors on the immune system. Very little is known about the influence of confinement or isolation on immune reactions. However, interesting data exist from experiments with animals and humans under different conditions (submarines, antarctic expeditions, single-person cave isolation, and underwater diving). The question remains as to whether these results can be extrapolated to spaceflight. Therefore, investigations of humans under isolation conditions analogous to space missions have been performed by Russian and, more recently, European investigators. Such investigations are important for understanding the physiological and psychological disturbances that occur during long periods of confinement, especially when future lunar and martian missions are considered. |
format |
Article in Journal/Newspaper |
author |
Schmitt, Didier A Schaffar, Laurence |
spellingShingle |
Schmitt, Didier A Schaffar, Laurence Isolation and confinement as a model for spaceflight Immune changes |
author_facet |
Schmitt, Didier A Schaffar, Laurence |
author_sort |
Schmitt, Didier A |
title |
Isolation and confinement as a model for spaceflight Immune changes |
title_short |
Isolation and confinement as a model for spaceflight Immune changes |
title_full |
Isolation and confinement as a model for spaceflight Immune changes |
title_fullStr |
Isolation and confinement as a model for spaceflight Immune changes |
title_full_unstemmed |
Isolation and confinement as a model for spaceflight Immune changes |
title_sort |
isolation and confinement as a model for spaceflight immune changes |
publisher |
Oxford University Press (OUP) |
publishDate |
1993 |
url |
http://dx.doi.org/10.1002/jlb.54.3.209 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjlb.54.3.209 https://academic.oup.com/jleukbio/article-pdf/54/3/209/49769374/jlb0209.pdf |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_source |
Journal of Leukocyte Biology volume 54, issue 3, page 209-213 ISSN 0741-5400 1938-3673 |
op_rights |
https://academic.oup.com/pages/standard-publication-reuse-rights |
op_doi |
https://doi.org/10.1002/jlb.54.3.209 |
container_title |
Journal of Leukocyte Biology |
container_volume |
54 |
container_issue |
3 |
container_start_page |
209 |
op_container_end_page |
213 |
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1810493415352172544 |