Time Trends in Incidence and Case Fatality of Ischemic Stroke
Background and Purpose— Ischemic stroke incidence has declined in industrialized countries the last decades, with possible exception for the youngest age groups. We estimated age- and sex-specific trends in incidence and case fatality of first-ever ischemic stroke between 1977 and 2010 in a Norwegia...
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Ovid Technologies (Wolters Kluwer Health)
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Online Access: | http://dx.doi.org/10.1161/strokeaha.114.008387 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.114.008387 |
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crovidcr:10.1161/strokeaha.114.008387 2024-09-30T14:45:09+00:00 Time Trends in Incidence and Case Fatality of Ischemic Stroke The Tromsø Study 1977–2010 Vangen-Lønne, Anne Merete Wilsgaard, Tom Johnsen, Stein Harald Carlsson, Maria Mathiesen, Ellisiv B. 2015 http://dx.doi.org/10.1161/strokeaha.114.008387 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.114.008387 en eng Ovid Technologies (Wolters Kluwer Health) Stroke volume 46, issue 5, page 1173-1179 ISSN 0039-2499 1524-4628 journal-article 2015 crovidcr https://doi.org/10.1161/strokeaha.114.008387 2024-09-05T05:00:02Z Background and Purpose— Ischemic stroke incidence has declined in industrialized countries the last decades, with possible exception for the youngest age groups. We estimated age- and sex-specific trends in incidence and case fatality of first-ever ischemic stroke between 1977 and 2010 in a Norwegian municipality. Methods— Age-adjusted time trends in incidence from 1977 to 2010 were estimated by fractional polynomial and Poisson regression, and case fatality by logistic regression in 36 575 participants of the population-based Tromsø Study. Results— There were 1214 first-ever ischemic strokes within a total follow-up time of 611 176 person-years. The overall age- and sex-adjusted incidence decreased by 24% in 1995 to 2010. In women aged 30 to 49 years, the incidence increased significantly from 1980 to 2010. In men aged 30 to 49 years, there was a nonsignificant, rising trend from 1977 to 2010. Men aged 50 to 64 years had similar incidence in 2010 compared with 1989. From the mid-1990s to 2010, the incidence declined significantly in women aged 50 to 74 years and in men aged 65 to 74 years, but remained stable in those aged ≥75 years. Case fatality decreased significantly in men aged 30 to 84 years from 1995 to 2010, whereas there was no significant change in women. Conclusions— Age-adjusted incidence of first-ever ischemic stroke increased in young women, declined in women aged 50 to 74 years and men aged 65 to 74 years and remained stable among the oldest. Case fatality declined in men aged 30 to 84 years, but not in women. Article in Journal/Newspaper Tromsø Ovid Tromsø Stroke 46 5 1173 1179 |
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Background and Purpose— Ischemic stroke incidence has declined in industrialized countries the last decades, with possible exception for the youngest age groups. We estimated age- and sex-specific trends in incidence and case fatality of first-ever ischemic stroke between 1977 and 2010 in a Norwegian municipality. Methods— Age-adjusted time trends in incidence from 1977 to 2010 were estimated by fractional polynomial and Poisson regression, and case fatality by logistic regression in 36 575 participants of the population-based Tromsø Study. Results— There were 1214 first-ever ischemic strokes within a total follow-up time of 611 176 person-years. The overall age- and sex-adjusted incidence decreased by 24% in 1995 to 2010. In women aged 30 to 49 years, the incidence increased significantly from 1980 to 2010. In men aged 30 to 49 years, there was a nonsignificant, rising trend from 1977 to 2010. Men aged 50 to 64 years had similar incidence in 2010 compared with 1989. From the mid-1990s to 2010, the incidence declined significantly in women aged 50 to 74 years and in men aged 65 to 74 years, but remained stable in those aged ≥75 years. Case fatality decreased significantly in men aged 30 to 84 years from 1995 to 2010, whereas there was no significant change in women. Conclusions— Age-adjusted incidence of first-ever ischemic stroke increased in young women, declined in women aged 50 to 74 years and men aged 65 to 74 years and remained stable among the oldest. Case fatality declined in men aged 30 to 84 years, but not in women. |
format |
Article in Journal/Newspaper |
author |
Vangen-Lønne, Anne Merete Wilsgaard, Tom Johnsen, Stein Harald Carlsson, Maria Mathiesen, Ellisiv B. |
spellingShingle |
Vangen-Lønne, Anne Merete Wilsgaard, Tom Johnsen, Stein Harald Carlsson, Maria Mathiesen, Ellisiv B. Time Trends in Incidence and Case Fatality of Ischemic Stroke |
author_facet |
Vangen-Lønne, Anne Merete Wilsgaard, Tom Johnsen, Stein Harald Carlsson, Maria Mathiesen, Ellisiv B. |
author_sort |
Vangen-Lønne, Anne Merete |
title |
Time Trends in Incidence and Case Fatality of Ischemic Stroke |
title_short |
Time Trends in Incidence and Case Fatality of Ischemic Stroke |
title_full |
Time Trends in Incidence and Case Fatality of Ischemic Stroke |
title_fullStr |
Time Trends in Incidence and Case Fatality of Ischemic Stroke |
title_full_unstemmed |
Time Trends in Incidence and Case Fatality of Ischemic Stroke |
title_sort |
time trends in incidence and case fatality of ischemic stroke |
publisher |
Ovid Technologies (Wolters Kluwer Health) |
publishDate |
2015 |
url |
http://dx.doi.org/10.1161/strokeaha.114.008387 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.114.008387 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
Stroke volume 46, issue 5, page 1173-1179 ISSN 0039-2499 1524-4628 |
op_doi |
https://doi.org/10.1161/strokeaha.114.008387 |
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Stroke |
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46 |
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5 |
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1173 |
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1179 |
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1811645989985976320 |