Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos
Background and Purpose— The recent increase in clinical cardiovascular disease in Alaska Eskimos suggests that changes in traditional lifestyle may have adverse public health consequences. This study examines the prevalence of subclinical vascular disease and its relation to risk factors in Alaska E...
Published in: | Stroke |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Ovid Technologies (Wolters Kluwer Health)
2008
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1161/strokeaha.108.519199 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.108.519199 |
id |
crovidcr:10.1161/strokeaha.108.519199 |
---|---|
record_format |
openpolar |
spelling |
crovidcr:10.1161/strokeaha.108.519199 2023-07-23T04:19:07+02:00 Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos The GOCADAN Study Cutchins, Alexis Roman, Mary J. Devereux, Richard B. Ebbesson, Sven O.E. Umans, Jason G. Zhu, Jianhui Weissman, Neil J. Howard, Barbara V. 2008 http://dx.doi.org/10.1161/strokeaha.108.519199 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.108.519199 en eng Ovid Technologies (Wolters Kluwer Health) Stroke volume 39, issue 11, page 3079-3082 ISSN 0039-2499 1524-4628 Advanced and Specialized Nursing Cardiology and Cardiovascular Medicine Neurology (clinical) journal-article 2008 crovidcr https://doi.org/10.1161/strokeaha.108.519199 2023-06-30T10:03:27Z Background and Purpose— The recent increase in clinical cardiovascular disease in Alaska Eskimos suggests that changes in traditional lifestyle may have adverse public health consequences. This study examines the prevalence of subclinical vascular disease and its relation to risk factors in Alaska Eskimos. Methods— Participants in the population-based Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) Study underwent evaluation of cardiovascular disease risk factors and carotid ultrasound. Outcome variables were carotid intimal-medial thickness and presence and extent of atherosclerosis. Results— In multivariate analyses, intimal-medial thickness and presence and extent of atherosclerosis were all associated with traditional cardiovascular disease risk factors but not dietary intake of omega-3 fatty acids. Rates of carotid atherosclerosis were higher than those reported in 2 large population-based US studies. Conclusions— Alaska Eskimos have similar traditional risk factors for carotid atherosclerosis as other ethnic and racial populations but have higher prevalences of atherosclerosis, possibly attributable to higher rates of smoking. Article in Journal/Newspaper eskimo* Alaska Ovid (via Crossref) Stroke 39 11 3079 3082 |
institution |
Open Polar |
collection |
Ovid (via Crossref) |
op_collection_id |
crovidcr |
language |
English |
topic |
Advanced and Specialized Nursing Cardiology and Cardiovascular Medicine Neurology (clinical) |
spellingShingle |
Advanced and Specialized Nursing Cardiology and Cardiovascular Medicine Neurology (clinical) Cutchins, Alexis Roman, Mary J. Devereux, Richard B. Ebbesson, Sven O.E. Umans, Jason G. Zhu, Jianhui Weissman, Neil J. Howard, Barbara V. Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos |
topic_facet |
Advanced and Specialized Nursing Cardiology and Cardiovascular Medicine Neurology (clinical) |
description |
Background and Purpose— The recent increase in clinical cardiovascular disease in Alaska Eskimos suggests that changes in traditional lifestyle may have adverse public health consequences. This study examines the prevalence of subclinical vascular disease and its relation to risk factors in Alaska Eskimos. Methods— Participants in the population-based Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) Study underwent evaluation of cardiovascular disease risk factors and carotid ultrasound. Outcome variables were carotid intimal-medial thickness and presence and extent of atherosclerosis. Results— In multivariate analyses, intimal-medial thickness and presence and extent of atherosclerosis were all associated with traditional cardiovascular disease risk factors but not dietary intake of omega-3 fatty acids. Rates of carotid atherosclerosis were higher than those reported in 2 large population-based US studies. Conclusions— Alaska Eskimos have similar traditional risk factors for carotid atherosclerosis as other ethnic and racial populations but have higher prevalences of atherosclerosis, possibly attributable to higher rates of smoking. |
format |
Article in Journal/Newspaper |
author |
Cutchins, Alexis Roman, Mary J. Devereux, Richard B. Ebbesson, Sven O.E. Umans, Jason G. Zhu, Jianhui Weissman, Neil J. Howard, Barbara V. |
author_facet |
Cutchins, Alexis Roman, Mary J. Devereux, Richard B. Ebbesson, Sven O.E. Umans, Jason G. Zhu, Jianhui Weissman, Neil J. Howard, Barbara V. |
author_sort |
Cutchins, Alexis |
title |
Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos |
title_short |
Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos |
title_full |
Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos |
title_fullStr |
Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos |
title_full_unstemmed |
Prevalence and Correlates of Subclinical Atherosclerosis in Alaska Eskimos |
title_sort |
prevalence and correlates of subclinical atherosclerosis in alaska eskimos |
publisher |
Ovid Technologies (Wolters Kluwer Health) |
publishDate |
2008 |
url |
http://dx.doi.org/10.1161/strokeaha.108.519199 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.108.519199 |
genre |
eskimo* Alaska |
genre_facet |
eskimo* Alaska |
op_source |
Stroke volume 39, issue 11, page 3079-3082 ISSN 0039-2499 1524-4628 |
op_doi |
https://doi.org/10.1161/strokeaha.108.519199 |
container_title |
Stroke |
container_volume |
39 |
container_issue |
11 |
container_start_page |
3079 |
op_container_end_page |
3082 |
_version_ |
1772181957617123328 |