Abstract 4405: Sequence Variant for Atrial Fibrillation on Chromosome 4q25 near the PITX2 Gene Increases Risk for Recurrent AF

• Published in: Circulation
• Main Authors: Gulcher, Jeffrey, Holm, Hilma, Gudbjartsson, Daniel, Arnar, David, Helgadottir, Anna, Gretarsdottir, Solveig, Thorsteinsdottir, Unnur, Stefansson, Kari
• Format: Article in Journal/Newspaper
• Language: English
• Published: Ovid Technologies (Wolters Kluwer Health) 2008
• Subjects: Physiology (medical); Cardiology and Cardiovascular Medicine; Lone; Iceland
• Online Access: http://dx.doi.org/10.1161/circ.118.suppl_18.s_883

Introduction. We have previously reported a strong association between two sequence variants on chromosome 4q25 and atrial fibrillation (AF) as the result of a genome-wide association study in Icelandic patients. This association has been replicated in three populations of European descent. About 35...