Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women
Background Geographical differences in stroke mortality are not fully explained by population variations in blood pressure and antihypertensive treatment. Some studies have suggested that factors connected with health and nutrition in early life may be related to stroke morbidity and mortality. Body...
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Ovid Technologies (Wolters Kluwer Health)
1996
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Online Access: | http://dx.doi.org/10.1161/01.cir.94.11.2877 https://www.ahajournals.org/doi/full/10.1161/01.CIR.94.11.2877 |
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crovidcr:10.1161/01.cir.94.11.2877 2024-09-15T18:06:14+00:00 Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women A 14-Year Follow-up of the Finnmark Study Njølstad, Inger Arnesen, Egil Lund-Larsen, Per G. 1996 http://dx.doi.org/10.1161/01.cir.94.11.2877 https://www.ahajournals.org/doi/full/10.1161/01.CIR.94.11.2877 en eng Ovid Technologies (Wolters Kluwer Health) Circulation volume 94, issue 11, page 2877-2882 ISSN 0009-7322 1524-4539 journal-article 1996 crovidcr https://doi.org/10.1161/01.cir.94.11.2877 2024-09-05T05:00:34Z Background Geographical differences in stroke mortality are not fully explained by population variations in blood pressure and antihypertensive treatment. Some studies have suggested that factors connected with health and nutrition in early life may be related to stroke morbidity and mortality. Body height is a sensitive marker for socioeconomic conditions, but results are conflicting as to whether height is associated with stroke. Methods and Results In a population-based study, we investigated stroke incidence in relation to height and classic cardiovascular risk factors. A total of 13 266 men and women 35 to 52 years of age were followed for 14 years, and 241 first events of stroke were registered. Stroke incidence was 36% higher in men. Height was inversely related to stroke in a dose-response manner. Per 5-cm increase in height, the age-adjusted risk of stroke was 25% lower in women ( P <.0001) and 18% lower in men ( P =.0007). Systolic blood pressure and daily smoking were positively associated with stroke in both sexes, while serum triglyceride level was a significant risk factor in women only (relative risk per 1 mmol/L, 1.3; 95% CI, 1.1 to 1.5). The associations remained after adjustment for possible confounders and were also observed in certain subtypes of stroke. Conclusions The results are consistent with the theory that factors influencing early growth as well as adult lifestyle factors contribute to cerebrovascular disease in adult age. Article in Journal/Newspaper Finnmark Finnmark Ovid Circulation 94 11 2877 2882 |
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Background Geographical differences in stroke mortality are not fully explained by population variations in blood pressure and antihypertensive treatment. Some studies have suggested that factors connected with health and nutrition in early life may be related to stroke morbidity and mortality. Body height is a sensitive marker for socioeconomic conditions, but results are conflicting as to whether height is associated with stroke. Methods and Results In a population-based study, we investigated stroke incidence in relation to height and classic cardiovascular risk factors. A total of 13 266 men and women 35 to 52 years of age were followed for 14 years, and 241 first events of stroke were registered. Stroke incidence was 36% higher in men. Height was inversely related to stroke in a dose-response manner. Per 5-cm increase in height, the age-adjusted risk of stroke was 25% lower in women ( P <.0001) and 18% lower in men ( P =.0007). Systolic blood pressure and daily smoking were positively associated with stroke in both sexes, while serum triglyceride level was a significant risk factor in women only (relative risk per 1 mmol/L, 1.3; 95% CI, 1.1 to 1.5). The associations remained after adjustment for possible confounders and were also observed in certain subtypes of stroke. Conclusions The results are consistent with the theory that factors influencing early growth as well as adult lifestyle factors contribute to cerebrovascular disease in adult age. |
format |
Article in Journal/Newspaper |
author |
Njølstad, Inger Arnesen, Egil Lund-Larsen, Per G. |
spellingShingle |
Njølstad, Inger Arnesen, Egil Lund-Larsen, Per G. Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women |
author_facet |
Njølstad, Inger Arnesen, Egil Lund-Larsen, Per G. |
author_sort |
Njølstad, Inger |
title |
Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women |
title_short |
Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women |
title_full |
Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women |
title_fullStr |
Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women |
title_full_unstemmed |
Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women |
title_sort |
body height, cardiovascular risk factors, and risk of stroke in middle-aged men and women |
publisher |
Ovid Technologies (Wolters Kluwer Health) |
publishDate |
1996 |
url |
http://dx.doi.org/10.1161/01.cir.94.11.2877 https://www.ahajournals.org/doi/full/10.1161/01.CIR.94.11.2877 |
genre |
Finnmark Finnmark |
genre_facet |
Finnmark Finnmark |
op_source |
Circulation volume 94, issue 11, page 2877-2882 ISSN 0009-7322 1524-4539 |
op_doi |
https://doi.org/10.1161/01.cir.94.11.2877 |
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Circulation |
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94 |
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11 |
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2877 |
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2882 |
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1810443714894495744 |