Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit
Background: Ischemic pancreatitis (IP) has mainly been described in case reports. The aims of the study were to assess the frequency, clinical characteristics and outcomes in patients with IP among patients hospitalized in the intensive care unit (ICU) for acute pancreatitis (AP). Methods: All patie...
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Ovid Technologies (Wolters Kluwer Health)
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Online Access: | http://dx.doi.org/10.1097/mcg.0000000000001651 https://journals.lww.com/10.1097/MCG.0000000000001651 |
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crovidcr:10.1097/mcg.0000000000001651 2024-01-21T10:07:27+01:00 Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit Baldursdottir, Maria B. Andresson, Johannes A. Jonsdottir, Sigrun Benediktsson, Halldor Kalaitzakis, Evangelos Bjornsson, Einar S. 2021 http://dx.doi.org/10.1097/mcg.0000000000001651 https://journals.lww.com/10.1097/MCG.0000000000001651 en eng Ovid Technologies (Wolters Kluwer Health) Journal of Clinical Gastroenterology volume 57, issue 1, page 97-102 ISSN 1539-2031 Gastroenterology journal-article 2021 crovidcr https://doi.org/10.1097/mcg.0000000000001651 2023-12-22T10:17:20Z Background: Ischemic pancreatitis (IP) has mainly been described in case reports. The aims of the study were to assess the frequency, clinical characteristics and outcomes in patients with IP among patients hospitalized in the intensive care unit (ICU) for acute pancreatitis (AP). Methods: All patients with first time AP between 2011 and 2018 in the ICU of Landspitali Hospital, Iceland were retrospectively included. IP as an etiology required a clinical setting of circulatory shock, arterial hypotension, hypovolemia and/or arterial hypoxemia [PaO 2 of 60 mm Hg (8.0 kPa), or less] before the diagnosis of AP without prior history of abdominal pain to this episode. Other causes of AP were ruled out. IP patients were compared with patients with AP of other etiologies, also hospitalized in the ICU. Results: Overall 67 patients with AP were identified (median age 60 y, 37% females), 31% idiopathic, 24% alcoholic, 22% IP, 15% biliary, and 8% other causes. Overall, 15 (22%) fulfilled the predetermined criteria for IP, 9 males (64%), median age 62 years (interquartile range: 46 to 65). IP was preceded mainly by systemic shock (73%). Other causes included dehydration, hypoxia, or vessel occlusion to the pancreas. Necrosis of the pancreas was rare with one patient requiring pancreatic necrosectomy. Inpatient mortality was higher among patients with IP than in other patients with AP (33% vs. 14%, P =0.12). Conclusions: IP was found in a significant proportion of AP patients hospitalized in the ICU. The main causes of IP were systemic shock and hypoxia. IP was associated with ∼30% mortality. Article in Journal/Newspaper Iceland Ovid (via Crossref) Journal of Clinical Gastroenterology 57 1 97 102 |
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Gastroenterology |
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Gastroenterology Baldursdottir, Maria B. Andresson, Johannes A. Jonsdottir, Sigrun Benediktsson, Halldor Kalaitzakis, Evangelos Bjornsson, Einar S. Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit |
topic_facet |
Gastroenterology |
description |
Background: Ischemic pancreatitis (IP) has mainly been described in case reports. The aims of the study were to assess the frequency, clinical characteristics and outcomes in patients with IP among patients hospitalized in the intensive care unit (ICU) for acute pancreatitis (AP). Methods: All patients with first time AP between 2011 and 2018 in the ICU of Landspitali Hospital, Iceland were retrospectively included. IP as an etiology required a clinical setting of circulatory shock, arterial hypotension, hypovolemia and/or arterial hypoxemia [PaO 2 of 60 mm Hg (8.0 kPa), or less] before the diagnosis of AP without prior history of abdominal pain to this episode. Other causes of AP were ruled out. IP patients were compared with patients with AP of other etiologies, also hospitalized in the ICU. Results: Overall 67 patients with AP were identified (median age 60 y, 37% females), 31% idiopathic, 24% alcoholic, 22% IP, 15% biliary, and 8% other causes. Overall, 15 (22%) fulfilled the predetermined criteria for IP, 9 males (64%), median age 62 years (interquartile range: 46 to 65). IP was preceded mainly by systemic shock (73%). Other causes included dehydration, hypoxia, or vessel occlusion to the pancreas. Necrosis of the pancreas was rare with one patient requiring pancreatic necrosectomy. Inpatient mortality was higher among patients with IP than in other patients with AP (33% vs. 14%, P =0.12). Conclusions: IP was found in a significant proportion of AP patients hospitalized in the ICU. The main causes of IP were systemic shock and hypoxia. IP was associated with ∼30% mortality. |
format |
Article in Journal/Newspaper |
author |
Baldursdottir, Maria B. Andresson, Johannes A. Jonsdottir, Sigrun Benediktsson, Halldor Kalaitzakis, Evangelos Bjornsson, Einar S. |
author_facet |
Baldursdottir, Maria B. Andresson, Johannes A. Jonsdottir, Sigrun Benediktsson, Halldor Kalaitzakis, Evangelos Bjornsson, Einar S. |
author_sort |
Baldursdottir, Maria B. |
title |
Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit |
title_short |
Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit |
title_full |
Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit |
title_fullStr |
Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit |
title_full_unstemmed |
Ischemic Pancreatitis Is an Important Cause of Acute Pancreatitis in the Intensive Care Unit |
title_sort |
ischemic pancreatitis is an important cause of acute pancreatitis in the intensive care unit |
publisher |
Ovid Technologies (Wolters Kluwer Health) |
publishDate |
2021 |
url |
http://dx.doi.org/10.1097/mcg.0000000000001651 https://journals.lww.com/10.1097/MCG.0000000000001651 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Journal of Clinical Gastroenterology volume 57, issue 1, page 97-102 ISSN 1539-2031 |
op_doi |
https://doi.org/10.1097/mcg.0000000000001651 |
container_title |
Journal of Clinical Gastroenterology |
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57 |
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1 |
container_start_page |
97 |
op_container_end_page |
102 |
_version_ |
1788698040934072320 |