Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort

Abstract Depression and musculoskeletal pain are associated, but long-term follow-up studies are rare. We aimed to examine the relationship of early depressive symptoms with developmental patterns of musculoskeletal pain from adolescence to middle age. Adolescents ending compulsory school (age 16) i...

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Published in:Pain
Main Authors: Leino-Arjas, Päivi, Rajaleid, Kristiina, Mekuria, Gashaw, Nummi, Tapio, Virtanen, Pekka, Hammarström, Anne
Format: Article in Journal/Newspaper
Language:English
Published: Ovid Technologies (Wolters Kluwer Health) 2017
Subjects:
Online Access:http://dx.doi.org/10.1097/j.pain.0000000000001065
https://journals.lww.com/00006396-201801000-00011
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spelling crovidcr:10.1097/j.pain.0000000000001065 2024-06-23T07:54:30+00:00 Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort Leino-Arjas, Päivi Rajaleid, Kristiina Mekuria, Gashaw Nummi, Tapio Virtanen, Pekka Hammarström, Anne 2017 http://dx.doi.org/10.1097/j.pain.0000000000001065 https://journals.lww.com/00006396-201801000-00011 en eng Ovid Technologies (Wolters Kluwer Health) Pain volume 159, issue 1, page 67-74 ISSN 0304-3959 1872-6623 journal-article 2017 crovidcr https://doi.org/10.1097/j.pain.0000000000001065 2024-06-11T04:13:24Z Abstract Depression and musculoskeletal pain are associated, but long-term follow-up studies are rare. We aimed to examine the relationship of early depressive symptoms with developmental patterns of musculoskeletal pain from adolescence to middle age. Adolescents ending compulsory school (age 16) in Luleå, Northern Sweden, in 1981 (n = 1083) were studied and followed up in 1986, 1995, and 2008 (age 43) for musculoskeletal pain. Attrition was very low. Indicators for any and severe pain were based on pain in the neck-shoulders, low back, and the extremities. Latent class growth analyses were performed on 563 men and 503 women. Associations of a depressive symptoms score (DSS, range 0.0-2.0) at age 16 with pain trajectory membership were assessed by logistic and multinomial regression, adjusting for parental socioeconomic status, social adversities, smoking, exercise, body mass index, and alcohol consumption at age 16. For any pain, 3 trajectories emerged: high-stable (women 71%, men 61%), moderate (11%, 17%), and low-increasing (18%, 22%). With the low-increasing trajectory as reference, for each 0.1-point increase in the DSS, the odds ratio of belonging to the high-stable trajectory was 1.25 (95% confidence interval 1.11-1.41) in women and 1.23 (1.10-1.37) in men. For severe pain, 2 trajectories were found: moderate-increasing (women 19%, men 9%) and low-stable. For each 0.1-point increase in the DSS, the odds ratio of membership in the moderate-increasing trajectory was 1.14 (1.04-1.25) in women and 1.17 (1.04-1.31) in men in the fully adjusted model. Thus, depressive symptoms at baseline are strongly associated with pain trajectory membership. Article in Journal/Newspaper Luleå Luleå Luleå Northern Sweden Ovid Pain 159 1 67 74
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description Abstract Depression and musculoskeletal pain are associated, but long-term follow-up studies are rare. We aimed to examine the relationship of early depressive symptoms with developmental patterns of musculoskeletal pain from adolescence to middle age. Adolescents ending compulsory school (age 16) in Luleå, Northern Sweden, in 1981 (n = 1083) were studied and followed up in 1986, 1995, and 2008 (age 43) for musculoskeletal pain. Attrition was very low. Indicators for any and severe pain were based on pain in the neck-shoulders, low back, and the extremities. Latent class growth analyses were performed on 563 men and 503 women. Associations of a depressive symptoms score (DSS, range 0.0-2.0) at age 16 with pain trajectory membership were assessed by logistic and multinomial regression, adjusting for parental socioeconomic status, social adversities, smoking, exercise, body mass index, and alcohol consumption at age 16. For any pain, 3 trajectories emerged: high-stable (women 71%, men 61%), moderate (11%, 17%), and low-increasing (18%, 22%). With the low-increasing trajectory as reference, for each 0.1-point increase in the DSS, the odds ratio of belonging to the high-stable trajectory was 1.25 (95% confidence interval 1.11-1.41) in women and 1.23 (1.10-1.37) in men. For severe pain, 2 trajectories were found: moderate-increasing (women 19%, men 9%) and low-stable. For each 0.1-point increase in the DSS, the odds ratio of membership in the moderate-increasing trajectory was 1.14 (1.04-1.25) in women and 1.17 (1.04-1.31) in men in the fully adjusted model. Thus, depressive symptoms at baseline are strongly associated with pain trajectory membership.
format Article in Journal/Newspaper
author Leino-Arjas, Päivi
Rajaleid, Kristiina
Mekuria, Gashaw
Nummi, Tapio
Virtanen, Pekka
Hammarström, Anne
spellingShingle Leino-Arjas, Päivi
Rajaleid, Kristiina
Mekuria, Gashaw
Nummi, Tapio
Virtanen, Pekka
Hammarström, Anne
Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort
author_facet Leino-Arjas, Päivi
Rajaleid, Kristiina
Mekuria, Gashaw
Nummi, Tapio
Virtanen, Pekka
Hammarström, Anne
author_sort Leino-Arjas, Päivi
title Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort
title_short Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort
title_full Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort
title_fullStr Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort
title_full_unstemmed Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort
title_sort trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the northern swedish cohort
publisher Ovid Technologies (Wolters Kluwer Health)
publishDate 2017
url http://dx.doi.org/10.1097/j.pain.0000000000001065
https://journals.lww.com/00006396-201801000-00011
genre Luleå
Luleå
Luleå
Northern Sweden
genre_facet Luleå
Luleå
Luleå
Northern Sweden
op_source Pain
volume 159, issue 1, page 67-74
ISSN 0304-3959 1872-6623
op_doi https://doi.org/10.1097/j.pain.0000000000001065
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