RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome
The Greenland shark (Somniosus microcephalus) is an enigmatic species known for its exceptional longevity and extraordinary adaptations to the cold environment. This animal lives in the arctic and subarctic regions of the North Atlantic Ocean. Surprisingly, even though it is a vertebrate with the lo...
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Online Access: | http://dx.doi.org/10.5817/cpr2023-2-17 https://journals.muni.cz/CPR/article/download/38141/32439 |
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crmasarykunivpr:10.5817/cpr2023-2-17 2024-05-19T07:36:07+00:00 RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav 2024 http://dx.doi.org/10.5817/cpr2023-2-17 https://journals.muni.cz/CPR/article/download/38141/32439 unknown Masaryk University Press Czech Polar Reports volume 13, issue 2 ISSN 1805-0697 1805-0689 journal-article 2024 crmasarykunivpr https://doi.org/10.5817/cpr2023-2-17 2024-04-30T06:41:28Z The Greenland shark (Somniosus microcephalus) is an enigmatic species known for its exceptional longevity and extraordinary adaptations to the cold environment. This animal lives in the arctic and subarctic regions of the North Atlantic Ocean. Surprisingly, even though it is a vertebrate with the longest known lifespan, its transcriptome has not been studied yet. Therefore, we isolated and analyzed RNA in the Greenland shark samples. Our findings reveal some important information about the possible genetic mechanisms that could contribute to its longevity. We identified a highly expressed long interspersed nuclear element-like transcript (LINE-like) that is supposed to be associated with extended lifespan and resilience to age-related diseases, possibly through an improved telomere maintenance mechanism. This research not only contributes to our understanding of the biology and evolution of the Greenland shark but could also have implications for human longevity research. Article in Journal/Newspaper Arctic Greenland North Atlantic Somniosus microcephalus Subarctic Munipress - Masaryk University Press Czech Polar Reports 13 2 |
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Munipress - Masaryk University Press |
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crmasarykunivpr |
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The Greenland shark (Somniosus microcephalus) is an enigmatic species known for its exceptional longevity and extraordinary adaptations to the cold environment. This animal lives in the arctic and subarctic regions of the North Atlantic Ocean. Surprisingly, even though it is a vertebrate with the longest known lifespan, its transcriptome has not been studied yet. Therefore, we isolated and analyzed RNA in the Greenland shark samples. Our findings reveal some important information about the possible genetic mechanisms that could contribute to its longevity. We identified a highly expressed long interspersed nuclear element-like transcript (LINE-like) that is supposed to be associated with extended lifespan and resilience to age-related diseases, possibly through an improved telomere maintenance mechanism. This research not only contributes to our understanding of the biology and evolution of the Greenland shark but could also have implications for human longevity research. |
format |
Article in Journal/Newspaper |
author |
Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav |
spellingShingle |
Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
author_facet |
Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav |
author_sort |
Bartas, Martin |
title |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_short |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_full |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_fullStr |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_full_unstemmed |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_sort |
rna analysis of the longest living vertebrate greenland shark revealed an abundance of line-like elements in its transcriptome |
publisher |
Masaryk University Press |
publishDate |
2024 |
url |
http://dx.doi.org/10.5817/cpr2023-2-17 https://journals.muni.cz/CPR/article/download/38141/32439 |
genre |
Arctic Greenland North Atlantic Somniosus microcephalus Subarctic |
genre_facet |
Arctic Greenland North Atlantic Somniosus microcephalus Subarctic |
op_source |
Czech Polar Reports volume 13, issue 2 ISSN 1805-0697 1805-0689 |
op_doi |
https://doi.org/10.5817/cpr2023-2-17 |
container_title |
Czech Polar Reports |
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13 |
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2 |
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1799475162717880320 |