Multidrug resistance 1 (MDR1) gene mutation in dogs
The multidrug resistance (MDR1) gene mutation in the domestic dog (Canis lupus familiaris) is an inherited condition most frequently observed in herding breeds. Dogs with the mutated gene are at risk of neurological toxicosis and life-threatening reactions if certain drugs are administered. Determin...
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Language: | English |
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Mark Allen Group
2024
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Online Access: | http://dx.doi.org/10.12968/vetn.2024.0019 http://www.magonlinelibrary.com/doi/pdf/10.12968/vetn.2024.0019 |
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crmarkallen:10.12968/vetn.2024.0019 2024-09-15T18:01:12+00:00 Multidrug resistance 1 (MDR1) gene mutation in dogs Hart, Katherine 2024 http://dx.doi.org/10.12968/vetn.2024.0019 http://www.magonlinelibrary.com/doi/pdf/10.12968/vetn.2024.0019 en eng Mark Allen Group The Veterinary Nurse volume 15, issue 5, page 198-202 ISSN 2044-0065 2052-2959 journal-article 2024 crmarkallen https://doi.org/10.12968/vetn.2024.0019 2024-07-04T04:14:05Z The multidrug resistance (MDR1) gene mutation in the domestic dog (Canis lupus familiaris) is an inherited condition most frequently observed in herding breeds. Dogs with the mutated gene are at risk of neurological toxicosis and life-threatening reactions if certain drugs are administered. Determining the MDR1 genotype of a dog via blood or buccal swab sampling will assist owners and veterinary professionals in understanding their risk of multidrug sensitivity. Some of the drugs known to be dangerous when administered to a dog with the mutation are used in everyday practice. To ensure patient safety, the student and registered veterinary nurse should have an understanding of this condition, particularly when dealing with the dog breeds at higher risk. This article aims to provide student and registered veterinary nurses with a comprehensive and logical analysis of the MDR1 gene mutation in dogs. Article in Journal/Newspaper Canis lupus Mark Allen The Veterinary Nurse 15 5 198 202 |
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Open Polar |
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Mark Allen |
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crmarkallen |
language |
English |
description |
The multidrug resistance (MDR1) gene mutation in the domestic dog (Canis lupus familiaris) is an inherited condition most frequently observed in herding breeds. Dogs with the mutated gene are at risk of neurological toxicosis and life-threatening reactions if certain drugs are administered. Determining the MDR1 genotype of a dog via blood or buccal swab sampling will assist owners and veterinary professionals in understanding their risk of multidrug sensitivity. Some of the drugs known to be dangerous when administered to a dog with the mutation are used in everyday practice. To ensure patient safety, the student and registered veterinary nurse should have an understanding of this condition, particularly when dealing with the dog breeds at higher risk. This article aims to provide student and registered veterinary nurses with a comprehensive and logical analysis of the MDR1 gene mutation in dogs. |
format |
Article in Journal/Newspaper |
author |
Hart, Katherine |
spellingShingle |
Hart, Katherine Multidrug resistance 1 (MDR1) gene mutation in dogs |
author_facet |
Hart, Katherine |
author_sort |
Hart, Katherine |
title |
Multidrug resistance 1 (MDR1) gene mutation in dogs |
title_short |
Multidrug resistance 1 (MDR1) gene mutation in dogs |
title_full |
Multidrug resistance 1 (MDR1) gene mutation in dogs |
title_fullStr |
Multidrug resistance 1 (MDR1) gene mutation in dogs |
title_full_unstemmed |
Multidrug resistance 1 (MDR1) gene mutation in dogs |
title_sort |
multidrug resistance 1 (mdr1) gene mutation in dogs |
publisher |
Mark Allen Group |
publishDate |
2024 |
url |
http://dx.doi.org/10.12968/vetn.2024.0019 http://www.magonlinelibrary.com/doi/pdf/10.12968/vetn.2024.0019 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_source |
The Veterinary Nurse volume 15, issue 5, page 198-202 ISSN 2044-0065 2052-2959 |
op_doi |
https://doi.org/10.12968/vetn.2024.0019 |
container_title |
The Veterinary Nurse |
container_volume |
15 |
container_issue |
5 |
container_start_page |
198 |
op_container_end_page |
202 |
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1810438388177698816 |