Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series
Objective: More specific strategies are needed to support children requiring skin grafting. Our goal was to identify procedures that reduce operating times, post-operative complications, pain and length of hospital stay. Patient safety, optimal wound bed support and quick micro-debridement with loco...
Published in: | Journal of Wound Care |
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Mark Allen Group
2022
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Online Access: | http://dx.doi.org/10.12968/jowc.2022.31.10.824 http://www.magonlinelibrary.com/doi/pdf/10.12968/jowc.2022.31.10.824 |
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crmarkallen:10.12968/jowc.2022.31.10.824 2024-09-15T17:55:36+00:00 Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series Ciprandi, Guido Kjartansson, Hilmar Grussu, Francesca Baldursson, Baldur T Frattaroli, Jacopo Urbani, Urbano Zama, Mario 2022 http://dx.doi.org/10.12968/jowc.2022.31.10.824 http://www.magonlinelibrary.com/doi/pdf/10.12968/jowc.2022.31.10.824 en eng Mark Allen Group Journal of Wound Care volume 31, issue 10, page 824-831 ISSN 0969-0700 2052-2916 journal-article 2022 crmarkallen https://doi.org/10.12968/jowc.2022.31.10.824 2024-09-05T04:56:55Z Objective: More specific strategies are needed to support children requiring skin grafting. Our goal was to identify procedures that reduce operating times, post-operative complications, pain and length of hospital stay. Patient safety, optimal wound bed support and quick micro-debridement with locoregional anaesthesia were prioritised. Ultimately, a novel acellular fish skin graft (FSG) derived from north Atlantic cod was selected for use. Method: We admitted consecutive paediatric patients with various lesions requiring skin grafting for definitive wound closure. All FSGs were applied and bolstered in the operating room following debridement. Results: In a cohort of 15 patients, the average age was 8 years and 9 months (4 years 1 month–13 years 5 months). Negative pressure wound therapy (NPWT) was given to 12 patients. Rapid wound healing was observed in all patients, with a wound area coverage of 100% and complete healing in 95% of wounds. Time until engraftment in patients receiving NPWT was reduced by about a half (to an average 12 days) from our standard experience of 21 days. Ten patients received locoregional anaesthesia and were discharged after day surgery. The operating time was <60 minutes, and no complications or allergic reactions were reported. Excellent pliability of the healed wound was achieved in all patients, without signs of itching and scratching in the postoperative period. This case series is the first and largest using FSG to treat paediatric patients with different wound aetiologies. We attribute the rapid transition to acute wound status and the good pliability of the new epidermal–dermal complex to the preserved molecular components of the FSG, including omega-3. Conclusion: FSG represents an innovative and sustainable solution for paediatric wound care that results in shorter surgery time and reduced hospital stays, with accelerated wound healing times. Article in Journal/Newspaper atlantic cod North Atlantic Mark Allen Journal of Wound Care 31 10 824 831 |
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Mark Allen |
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crmarkallen |
language |
English |
description |
Objective: More specific strategies are needed to support children requiring skin grafting. Our goal was to identify procedures that reduce operating times, post-operative complications, pain and length of hospital stay. Patient safety, optimal wound bed support and quick micro-debridement with locoregional anaesthesia were prioritised. Ultimately, a novel acellular fish skin graft (FSG) derived from north Atlantic cod was selected for use. Method: We admitted consecutive paediatric patients with various lesions requiring skin grafting for definitive wound closure. All FSGs were applied and bolstered in the operating room following debridement. Results: In a cohort of 15 patients, the average age was 8 years and 9 months (4 years 1 month–13 years 5 months). Negative pressure wound therapy (NPWT) was given to 12 patients. Rapid wound healing was observed in all patients, with a wound area coverage of 100% and complete healing in 95% of wounds. Time until engraftment in patients receiving NPWT was reduced by about a half (to an average 12 days) from our standard experience of 21 days. Ten patients received locoregional anaesthesia and were discharged after day surgery. The operating time was <60 minutes, and no complications or allergic reactions were reported. Excellent pliability of the healed wound was achieved in all patients, without signs of itching and scratching in the postoperative period. This case series is the first and largest using FSG to treat paediatric patients with different wound aetiologies. We attribute the rapid transition to acute wound status and the good pliability of the new epidermal–dermal complex to the preserved molecular components of the FSG, including omega-3. Conclusion: FSG represents an innovative and sustainable solution for paediatric wound care that results in shorter surgery time and reduced hospital stays, with accelerated wound healing times. |
format |
Article in Journal/Newspaper |
author |
Ciprandi, Guido Kjartansson, Hilmar Grussu, Francesca Baldursson, Baldur T Frattaroli, Jacopo Urbani, Urbano Zama, Mario |
spellingShingle |
Ciprandi, Guido Kjartansson, Hilmar Grussu, Francesca Baldursson, Baldur T Frattaroli, Jacopo Urbani, Urbano Zama, Mario Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series |
author_facet |
Ciprandi, Guido Kjartansson, Hilmar Grussu, Francesca Baldursson, Baldur T Frattaroli, Jacopo Urbani, Urbano Zama, Mario |
author_sort |
Ciprandi, Guido |
title |
Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series |
title_short |
Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series |
title_full |
Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series |
title_fullStr |
Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series |
title_full_unstemmed |
Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series |
title_sort |
use of acellular intact fish skin grafts in treating acute paediatric wounds during the covid-19 pandemic: a case series |
publisher |
Mark Allen Group |
publishDate |
2022 |
url |
http://dx.doi.org/10.12968/jowc.2022.31.10.824 http://www.magonlinelibrary.com/doi/pdf/10.12968/jowc.2022.31.10.824 |
genre |
atlantic cod North Atlantic |
genre_facet |
atlantic cod North Atlantic |
op_source |
Journal of Wound Care volume 31, issue 10, page 824-831 ISSN 0969-0700 2052-2916 |
op_doi |
https://doi.org/10.12968/jowc.2022.31.10.824 |
container_title |
Journal of Wound Care |
container_volume |
31 |
container_issue |
10 |
container_start_page |
824 |
op_container_end_page |
831 |
_version_ |
1810431859017908224 |