Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study
Objectives To assess the distribution and spending by cost-effectiveness category among those drugs with the highest public spending levels in Canada. Design Repeated cross-sectional study. Setting The Canadian provinces of Manitoba, Ontario, New Brunswick, Nova Scotia, Prince Edward Island and Newf...
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Online Access: | http://dx.doi.org/10.1136/bmjopen-2023-082568 https://syndication.highwire.org/content/doi/10.1136/bmjopen-2023-082568 |
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crjcrbmj:10.1136/bmjopen-2023-082568 2024-05-19T07:44:19+00:00 Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study Gaudette, Étienne Rizzardo, Shirin Zhang, Yvonne Pothier, Kevin R Tadrous, Mina 2024 http://dx.doi.org/10.1136/bmjopen-2023-082568 https://syndication.highwire.org/content/doi/10.1136/bmjopen-2023-082568 en eng BMJ http://creativecommons.org/licenses/by-nc/4.0/ BMJ Open volume 14, issue 3, page e082568 ISSN 2044-6055 2044-6055 journal-article 2024 crjcrbmj https://doi.org/10.1136/bmjopen-2023-082568 2024-05-02T09:26:42Z Objectives To assess the distribution and spending by cost-effectiveness category among those drugs with the highest public spending levels in Canada. Design Repeated cross-sectional study. Setting The Canadian provinces of Manitoba, Ontario, New Brunswick, Nova Scotia, Prince Edward Island and Newfoundland. Main outcomes and measures Cost-effectiveness assessments by the Canadian Agency for Drugs and Technologies in Health (CADTH) for top-100 brand-name outpatient drugs by gross public plan spending in any year between 2015 and 2021 in Canada Institute for Health Information’s National Prescription Drug Utilization Information System data. Gross public plan spending by cost-effectiveness category. Results From 2015 to 2021, 152 brand-name drugs occupied a top-100 rank and were included in the analysis. Of those, 117 had been assessed by CADTH. During the 7-year period, there was an increase in both top-100 drugs with cost-effective (from 18 to 24) and cost-ineffective (from 29 to 41) assessments, while drugs not assessed or with an unclear assessment declined (from 31 to 19 and from 22 to 16, respectively). As a share of spending on top-100 drugs with an assessment, spending on cost-effective drugs was mostly stable at 40%–46% from 2015 to 2021, while spending on cost-ineffective drugs increased from 30% to 45%. Conclusion A large and growing share of public drug spending has been allocated to cost-ineffective drugs in Canada. Dedicating large budgets to such treatments prevents spending with greater health impact elsewhere in the healthcare system and could restrain the capacity to pay for groundbreaking pharmaceutical innovation in the future. Article in Journal/Newspaper Newfoundland Prince Edward Island The BMJ BMJ Open 14 3 e082568 |
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Objectives To assess the distribution and spending by cost-effectiveness category among those drugs with the highest public spending levels in Canada. Design Repeated cross-sectional study. Setting The Canadian provinces of Manitoba, Ontario, New Brunswick, Nova Scotia, Prince Edward Island and Newfoundland. Main outcomes and measures Cost-effectiveness assessments by the Canadian Agency for Drugs and Technologies in Health (CADTH) for top-100 brand-name outpatient drugs by gross public plan spending in any year between 2015 and 2021 in Canada Institute for Health Information’s National Prescription Drug Utilization Information System data. Gross public plan spending by cost-effectiveness category. Results From 2015 to 2021, 152 brand-name drugs occupied a top-100 rank and were included in the analysis. Of those, 117 had been assessed by CADTH. During the 7-year period, there was an increase in both top-100 drugs with cost-effective (from 18 to 24) and cost-ineffective (from 29 to 41) assessments, while drugs not assessed or with an unclear assessment declined (from 31 to 19 and from 22 to 16, respectively). As a share of spending on top-100 drugs with an assessment, spending on cost-effective drugs was mostly stable at 40%–46% from 2015 to 2021, while spending on cost-ineffective drugs increased from 30% to 45%. Conclusion A large and growing share of public drug spending has been allocated to cost-ineffective drugs in Canada. Dedicating large budgets to such treatments prevents spending with greater health impact elsewhere in the healthcare system and could restrain the capacity to pay for groundbreaking pharmaceutical innovation in the future. |
format |
Article in Journal/Newspaper |
author |
Gaudette, Étienne Rizzardo, Shirin Zhang, Yvonne Pothier, Kevin R Tadrous, Mina |
spellingShingle |
Gaudette, Étienne Rizzardo, Shirin Zhang, Yvonne Pothier, Kevin R Tadrous, Mina Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study |
author_facet |
Gaudette, Étienne Rizzardo, Shirin Zhang, Yvonne Pothier, Kevin R Tadrous, Mina |
author_sort |
Gaudette, Étienne |
title |
Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study |
title_short |
Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study |
title_full |
Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study |
title_fullStr |
Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study |
title_full_unstemmed |
Cost-effectiveness of the top 100 drugs by public spending in Canada, 2015–2021: a repeated cross-sectional study |
title_sort |
cost-effectiveness of the top 100 drugs by public spending in canada, 2015–2021: a repeated cross-sectional study |
publisher |
BMJ |
publishDate |
2024 |
url |
http://dx.doi.org/10.1136/bmjopen-2023-082568 https://syndication.highwire.org/content/doi/10.1136/bmjopen-2023-082568 |
genre |
Newfoundland Prince Edward Island |
genre_facet |
Newfoundland Prince Edward Island |
op_source |
BMJ Open volume 14, issue 3, page e082568 ISSN 2044-6055 2044-6055 |
op_rights |
http://creativecommons.org/licenses/by-nc/4.0/ |
op_doi |
https://doi.org/10.1136/bmjopen-2023-082568 |
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BMJ Open |
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14 |
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3 |
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e082568 |
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