Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis
Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. Methods: Case–control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invi...
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Online Access: | http://dx.doi.org/10.1136/ard.2007.086868 https://syndication.highwire.org/content/doi/10.1136/ard.2007.086868 |
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crjcrbmj:10.1136/ard.2007.086868 2024-06-23T07:54:04+00:00 Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis Franklin, J Ingvarsson, T Englund, M Lohmander, L S 2008 http://dx.doi.org/10.1136/ard.2007.086868 https://syndication.highwire.org/content/doi/10.1136/ard.2007.086868 en eng BMJ Annals of the Rheumatic Diseases volume 68, issue 4, page 536-540 ISSN 0003-4967 1468-2060 journal-article 2008 crjcrbmj https://doi.org/10.1136/ard.2007.086868 2024-05-24T13:15:57Z Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. Methods: Case–control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. First-degree relatives of participating patients served as controls. A total of 1473 patients (872 women) and 1103 controls (599 women), all born between 1910 and 1939 and who had answered a questionnaire including questions about height and weight, were analysed. A randomly selected sample, representative of the Icelandic population, was used as a secondary control group. Results: The OR, adjusted for age, occupation and presence of hand OA, for having a THR was 1.1 (95% CI 0.9 to 1.5) for overweight men and 1.7 (95% CI 1.0 to 2.9) for obese men. The OR for having a TKR was 1.7 (95% CI 1.1 to 2.6) for overweight men and 5.3 (95% CI 2.8 to 10.1) for obese men. The OR for having a THR was 1.0 (95% CI 0.8 to 1.3) for overweight women and 1.0 (95% CI 0.6 to 1.5) for obese women. The OR for having a TKR was 1.6 (95% CI 1.1 to 2.2) for overweight women and 4.0 (95% CI 2.6 to 6.1) for obese women. Conclusion: This study supports a positive association between high BMI and TKR in both sexes, but for THR the association with BMI seems to be weaker, and possibly negligible for women. Article in Journal/Newspaper Iceland The BMJ Annals of the Rheumatic Diseases 68 4 536 540 |
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description |
Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. Methods: Case–control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. First-degree relatives of participating patients served as controls. A total of 1473 patients (872 women) and 1103 controls (599 women), all born between 1910 and 1939 and who had answered a questionnaire including questions about height and weight, were analysed. A randomly selected sample, representative of the Icelandic population, was used as a secondary control group. Results: The OR, adjusted for age, occupation and presence of hand OA, for having a THR was 1.1 (95% CI 0.9 to 1.5) for overweight men and 1.7 (95% CI 1.0 to 2.9) for obese men. The OR for having a TKR was 1.7 (95% CI 1.1 to 2.6) for overweight men and 5.3 (95% CI 2.8 to 10.1) for obese men. The OR for having a THR was 1.0 (95% CI 0.8 to 1.3) for overweight women and 1.0 (95% CI 0.6 to 1.5) for obese women. The OR for having a TKR was 1.6 (95% CI 1.1 to 2.2) for overweight women and 4.0 (95% CI 2.6 to 6.1) for obese women. Conclusion: This study supports a positive association between high BMI and TKR in both sexes, but for THR the association with BMI seems to be weaker, and possibly negligible for women. |
format |
Article in Journal/Newspaper |
author |
Franklin, J Ingvarsson, T Englund, M Lohmander, L S |
spellingShingle |
Franklin, J Ingvarsson, T Englund, M Lohmander, L S Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
author_facet |
Franklin, J Ingvarsson, T Englund, M Lohmander, L S |
author_sort |
Franklin, J |
title |
Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
title_short |
Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
title_full |
Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
title_fullStr |
Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
title_full_unstemmed |
Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
title_sort |
sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis |
publisher |
BMJ |
publishDate |
2008 |
url |
http://dx.doi.org/10.1136/ard.2007.086868 https://syndication.highwire.org/content/doi/10.1136/ard.2007.086868 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Annals of the Rheumatic Diseases volume 68, issue 4, page 536-540 ISSN 0003-4967 1468-2060 |
op_doi |
https://doi.org/10.1136/ard.2007.086868 |
container_title |
Annals of the Rheumatic Diseases |
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68 |
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4 |
container_start_page |
536 |
op_container_end_page |
540 |
_version_ |
1802646025492496384 |