AB0605 ACTIGRAPHY-BASED PHYSICAL ACTIVITY MONITORING IN PATIENTS WITH KNEE OSTEOARTHRITIS AND COMORBID FIBROMYALGIA

• Published in: Annals of the Rheumatic Diseases
• Main Author: Dzekan, O.
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMJ 2021
• Subjects: General Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology; Northern Sweden
• Online Access: http://dx.doi.org/10.1136/annrheumdis-2021-eular.4189; https://syndication.highwire.org/content/doi/10.1136/annrheumdis-2021-eular.4189

Background: Low physical activity (PA) levels are common in patients with diseases associated with pain syndrome, such as osteoarthritis (OA) of the knee joints. Recent studies show that OA may be accompanied by concomitant fibromyalgia (FM) – a chronic pain syndrome associated with sedentary behavior [1]. As far as low PA levels are associated with poor quality of life and higher all-cause mortality, PA measurement in patients with knee OA and concomitant FM is of considerable interest [2,3]. Objectives: The aim of this study was to investigate and compare physical activity measured by an actigraph in knee OA patients with and without comorbid FM. Methods: A total of 70 patients with painful knee osteoarthritis (OA) – 35 subjects - (30 females and 5 males) with concomitant fibromyalgia (FM) aged 59.8±14.9 (M±SD) years and 35 patients (30 females and 5 males) without concomitant FM aged 58.5±15.7 (M±SD) years were enrolled in the study. 35 healthy controls of the same age and gender underwent the same investigation. OA diagnosis was established according to ACR 1986 Osteoarthritis Knee Criteria. FM was diagnosed if both modified 2010 ACR diagnostic criteria and 2016 Fibromyalgia Diagnostic Criteria were met. All participants wore an actigraph (GT3X model accelerometer) on the wrist for the period of 5 working days. Average daily minutes in light, moderate and vigorous PA were calculated. Results: All OA patients with and without FM spent significantly less time in vigorous PA compared to controls. Obtained results did not indicate significant difference between time in vigorous activity in OA patients with and without FM. Patients with OA alone showed insignificant decrease in time in moderate activity in comparison with healthy subjects. OA patients with comorbid FM showed significantly less time in moderate activity compared to OA patients without FM and healthy individuals. Conclusion: Our study results revealed that patients with painful knee OA and comorbid FM have greater activity limitations than patients with painful knee OA alone and healthy individuals. References: [1]Mahgoub MY, Elnady BM, Abdelkader HS, Abdelhalem RA, HassanWA. Comorbidity of Fibromyalgia in Primary Knee Osteoarthritis: Potential Impact on Functional Status and Quality of Life. Open Access Rheumatol. 2020;12: 55—63. [2]Ali K. Q. Al-Rubaye, Klara Johansson, Laith Alrubaiy. The association of health behavioral risk factors with quality of life in northern Sweden—A cross-sectional survey. J Gen Fam Med. 2020 Sep; 21(5): 167–177. [3]GBD 2017 Mortality Collaborators. Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1684–735. pmid:30496102 Disclosure of Interests: None declared.