Ecological and biological aspects of the impact of industrial pollution on cellular and humoral immunity of residents of the Arctic latitudes (on the example of the Murmansk region and the Republic of Karelia)
Abstract The article presents the results of years of research aimed at investigating the influence of various immunotropic environmental factors on the nonspecific immunity of residents of the Murmansk region and the Republic of Karelia. The authors studied 2011 adults (adults) from 2001 to 2016, n...
| Published in: | IOP Conference Series: Earth and Environmental Science |
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| Main Authors: | , , , |
| Format: | Article in Journal/Newspaper |
| Language: | unknown |
| Published: |
IOP Publishing
2019
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1088/1755-1315/302/1/012082 https://iopscience.iop.org/article/10.1088/1755-1315/302/1/012082/pdf https://iopscience.iop.org/article/10.1088/1755-1315/302/1/012082 |
| Summary: | Abstract The article presents the results of years of research aimed at investigating the influence of various immunotropic environmental factors on the nonspecific immunity of residents of the Murmansk region and the Republic of Karelia. The authors studied 2011 adults (adults) from 2001 to 2016, namely the indicators of nonspecific immunity - cell and humoral immunity of a representative sample: buccal test, skin bactericidal activity, cytochemical study (glycogen, alkaline phosphatase) of peripheral blood and white cells blood count. The subjects’ gender, age, length of residence in northern latitudes, the presence of chronic diseases, etc. were analyzed in detail. It describes the statistical data of target regions, level of industrial pollution, and features of climatic conditions. The studied indicators of nonspecific resistance of the residents of the Murmansk region, on average, are within the normal range, in contrast to similar indicators in the inhabitants of Karelia. An analysis of the research has shown that blood parameters determine compensatory-adaptive processes in combination with indicators of nonspecific immunity when a person adapts to adverse conditions of industrial cities and climatic factors. The emergence of such dependencies indicates the activation of metabolism and increase the work of reserve immune systems to maintain life safety. The following blood counts reacted to the regional and industrial factors: glycogen in lymphocytes and neutrophils, basophils, monocytes, leukocytes, segmented neutrophils. The methods of research of nonspecific resistance of the organism can be recommended as one of the criteria for the influence of environmental factors on the state of the human body as a whole. |
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