Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study
Introduction Cognitive impairment is one of the main disabilities in dementia. Physical activity (PA) has been suggested as protective for dementia. However, the findings are disparate in studies, and the question of whether this is because of reverse causality is still open. We aimed to explore the...
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crfrontiers:10.3389/fnagi.2022.906678 2024-09-15T18:39:27+00:00 Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik 2022 http://dx.doi.org/10.3389/fnagi.2022.906678 https://www.frontiersin.org/articles/10.3389/fnagi.2022.906678/full unknown Frontiers Media SA https://creativecommons.org/licenses/by/4.0/ Frontiers in Aging Neuroscience volume 14 ISSN 1663-4365 journal-article 2022 crfrontiers https://doi.org/10.3389/fnagi.2022.906678 2024-08-06T04:06:07Z Introduction Cognitive impairment is one of the main disabilities in dementia. Physical activity (PA) has been suggested as protective for dementia. However, the findings are disparate in studies, and the question of whether this is because of reverse causality is still open. We aimed to explore the association of PA with cognition in people who later developed dementia compared to those who did not. Method Since 2001, 11,512 (55% women) participants over the age of 50 years had taken at least one cognitive test in the Tromsø Study. Of these, 1,123 (58% women) later developed dementia. The cases were extracted from hospital journals and entered into an endpoint registry. Leisure time PA (LTPA) was self-reported. Multilevel mixed-effects linear regression was used to address whether LTPA was associated with cognition, stratified by those later developing dementia, and dementia-free in a separate analysis. Results Leisure time PA was associated with scores in cognitive tests that were 55% (z-score 0.14) higher in those who did not develop dementia. For those in a preclinical phase of dementia, there was no association with LTPA on global cognitive scores. However, in a multifactorial test on processing speed and memory, women had a positive association with processing speed and memory. Conclusion Leisure time PA had a positive association with global cognition function only for those who did not develop dementia. In women who were developing dementia, LTPA had a positive association with processing speed and memory, while in men, there were no such associations. Article in Journal/Newspaper Tromsø Frontiers (Publisher) Frontiers in Aging Neuroscience 14 |
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Introduction Cognitive impairment is one of the main disabilities in dementia. Physical activity (PA) has been suggested as protective for dementia. However, the findings are disparate in studies, and the question of whether this is because of reverse causality is still open. We aimed to explore the association of PA with cognition in people who later developed dementia compared to those who did not. Method Since 2001, 11,512 (55% women) participants over the age of 50 years had taken at least one cognitive test in the Tromsø Study. Of these, 1,123 (58% women) later developed dementia. The cases were extracted from hospital journals and entered into an endpoint registry. Leisure time PA (LTPA) was self-reported. Multilevel mixed-effects linear regression was used to address whether LTPA was associated with cognition, stratified by those later developing dementia, and dementia-free in a separate analysis. Results Leisure time PA was associated with scores in cognitive tests that were 55% (z-score 0.14) higher in those who did not develop dementia. For those in a preclinical phase of dementia, there was no association with LTPA on global cognitive scores. However, in a multifactorial test on processing speed and memory, women had a positive association with processing speed and memory. Conclusion Leisure time PA had a positive association with global cognition function only for those who did not develop dementia. In women who were developing dementia, LTPA had a positive association with processing speed and memory, while in men, there were no such associations. |
format |
Article in Journal/Newspaper |
author |
Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik |
spellingShingle |
Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
author_facet |
Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik |
author_sort |
Johnsen, Bente |
title |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_short |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_full |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_fullStr |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_full_unstemmed |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_sort |
leisure time physical activities’ association with cognition and dementia: a 19 years’ life course study |
publisher |
Frontiers Media SA |
publishDate |
2022 |
url |
http://dx.doi.org/10.3389/fnagi.2022.906678 https://www.frontiersin.org/articles/10.3389/fnagi.2022.906678/full |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
Frontiers in Aging Neuroscience volume 14 ISSN 1663-4365 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3389/fnagi.2022.906678 |
container_title |
Frontiers in Aging Neuroscience |
container_volume |
14 |
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1810483826705563648 |