Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic
The present study was undertaken to address the recent spate of pasteurellosis outbreaks among sea-farmed Atlantic salmon ( Salmo salar ) in Norway and Scotland, coinciding with sporadic disease episodes in lumpfish ( Cyclopterus lumpus ) used for delousing purposes in salmon farms. Genome assemblie...
Published in: | Frontiers in Microbiology |
---|---|
Main Authors: | , , , , , , , , , |
Other Authors: | , |
Format: | Article in Journal/Newspaper |
Language: | unknown |
Published: |
Frontiers Media SA
2023
|
Subjects: | |
Online Access: | http://dx.doi.org/10.3389/fmicb.2023.1236290 https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236290/full |
id |
crfrontiers:10.3389/fmicb.2023.1236290 |
---|---|
record_format |
openpolar |
spelling |
crfrontiers:10.3389/fmicb.2023.1236290 2024-02-11T10:02:13+01:00 Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic Gulla, Snorre Colquhoun, Duncan J. Olsen, Anne Berit Spilsberg, Bjørn Lagesen, Karin Åkesson, Caroline P. Strøm, Sverri Manji, Farah Birkbeck, Thomas H. Nilsen, Hanne K. Fiskeri - og havbruksnæringens forskningsfond Veterinærinstituttets 2023 http://dx.doi.org/10.3389/fmicb.2023.1236290 https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236290/full unknown Frontiers Media SA https://creativecommons.org/licenses/by/4.0/ Frontiers in Microbiology volume 14 ISSN 1664-302X Microbiology (medical) Microbiology journal-article 2023 crfrontiers https://doi.org/10.3389/fmicb.2023.1236290 2024-01-26T09:58:08Z The present study was undertaken to address the recent spate of pasteurellosis outbreaks among sea-farmed Atlantic salmon ( Salmo salar ) in Norway and Scotland, coinciding with sporadic disease episodes in lumpfish ( Cyclopterus lumpus ) used for delousing purposes in salmon farms. Genome assemblies from 86 bacterial isolates cultured from diseased salmon or lumpfish confirmed them all as bona fide members of the Pasteurellaceae family, with phylogenetic reconstruction dividing them into two distinct branches sharing <88% average nucleotide identity. These branches therefore constitute two separate species, namely Pasteurella skyensis and the as-yet invalidly named “ Pasteurella atlantica ”. Both species further stratify into multiple discrete genomovars (gv.) and/or lineages, each being nearly or fully exclusive to a particular host, geographic region, and/or time period. Pasteurellosis in lumpfish is, irrespective of spatiotemporal origin, linked almost exclusively to the highly conserved “ P. atlantica gv. cyclopteri ” (Pac). In contrast, pasteurellosis in Norwegian sea-farmed salmon, dominated since the late-1980s by “ P. atlantica gv. salmonicida ” (Pas), first saw three specific lineages (Pas-1, -2, and -3) causing separate, geographically restricted, and short-lived outbreaks, before a fourth (Pas-4) emerged recently and became more widely disseminated. A similar situation involving P. skyensis (Ps) has apparently been unfolding in Scottish salmon farming since the mid-1990s, where two historic (Ps-1 and -2) and one contemporary (Ps-3) lineages have been recorded. While the epidemiology underlying all these outbreaks/epizootics remains unclear, repeated detection of 16S rRNA gene amplicons very closely related to P. skyensis and “ P. atlantica ” from at least five cetacean species worldwide raises the question as to whether marine mammals may play a part, possibly as reservoirs. In fact, the close relationship between the studied isolates and Phocoenobacter uteri associated with harbor porpoise ( ... Article in Journal/Newspaper Atlantic salmon North East Atlantic Norwegian Sea Salmo salar Frontiers (Publisher) Norway Norwegian Sea Spate ENVELOPE(76.102,76.102,-69.418,-69.418) Frontiers in Microbiology 14 |
institution |
Open Polar |
collection |
Frontiers (Publisher) |
op_collection_id |
crfrontiers |
language |
unknown |
topic |
Microbiology (medical) Microbiology |
spellingShingle |
Microbiology (medical) Microbiology Gulla, Snorre Colquhoun, Duncan J. Olsen, Anne Berit Spilsberg, Bjørn Lagesen, Karin Åkesson, Caroline P. Strøm, Sverri Manji, Farah Birkbeck, Thomas H. Nilsen, Hanne K. Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic |
topic_facet |
Microbiology (medical) Microbiology |
description |
The present study was undertaken to address the recent spate of pasteurellosis outbreaks among sea-farmed Atlantic salmon ( Salmo salar ) in Norway and Scotland, coinciding with sporadic disease episodes in lumpfish ( Cyclopterus lumpus ) used for delousing purposes in salmon farms. Genome assemblies from 86 bacterial isolates cultured from diseased salmon or lumpfish confirmed them all as bona fide members of the Pasteurellaceae family, with phylogenetic reconstruction dividing them into two distinct branches sharing <88% average nucleotide identity. These branches therefore constitute two separate species, namely Pasteurella skyensis and the as-yet invalidly named “ Pasteurella atlantica ”. Both species further stratify into multiple discrete genomovars (gv.) and/or lineages, each being nearly or fully exclusive to a particular host, geographic region, and/or time period. Pasteurellosis in lumpfish is, irrespective of spatiotemporal origin, linked almost exclusively to the highly conserved “ P. atlantica gv. cyclopteri ” (Pac). In contrast, pasteurellosis in Norwegian sea-farmed salmon, dominated since the late-1980s by “ P. atlantica gv. salmonicida ” (Pas), first saw three specific lineages (Pas-1, -2, and -3) causing separate, geographically restricted, and short-lived outbreaks, before a fourth (Pas-4) emerged recently and became more widely disseminated. A similar situation involving P. skyensis (Ps) has apparently been unfolding in Scottish salmon farming since the mid-1990s, where two historic (Ps-1 and -2) and one contemporary (Ps-3) lineages have been recorded. While the epidemiology underlying all these outbreaks/epizootics remains unclear, repeated detection of 16S rRNA gene amplicons very closely related to P. skyensis and “ P. atlantica ” from at least five cetacean species worldwide raises the question as to whether marine mammals may play a part, possibly as reservoirs. In fact, the close relationship between the studied isolates and Phocoenobacter uteri associated with harbor porpoise ( ... |
author2 |
Fiskeri - og havbruksnæringens forskningsfond Veterinærinstituttets |
format |
Article in Journal/Newspaper |
author |
Gulla, Snorre Colquhoun, Duncan J. Olsen, Anne Berit Spilsberg, Bjørn Lagesen, Karin Åkesson, Caroline P. Strøm, Sverri Manji, Farah Birkbeck, Thomas H. Nilsen, Hanne K. |
author_facet |
Gulla, Snorre Colquhoun, Duncan J. Olsen, Anne Berit Spilsberg, Bjørn Lagesen, Karin Åkesson, Caroline P. Strøm, Sverri Manji, Farah Birkbeck, Thomas H. Nilsen, Hanne K. |
author_sort |
Gulla, Snorre |
title |
Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic |
title_short |
Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic |
title_full |
Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic |
title_fullStr |
Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic |
title_full_unstemmed |
Phylogeography and host specificity of Pasteurellaceae pathogenic to sea-farmed fish in the north-east Atlantic |
title_sort |
phylogeography and host specificity of pasteurellaceae pathogenic to sea-farmed fish in the north-east atlantic |
publisher |
Frontiers Media SA |
publishDate |
2023 |
url |
http://dx.doi.org/10.3389/fmicb.2023.1236290 https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236290/full |
long_lat |
ENVELOPE(76.102,76.102,-69.418,-69.418) |
geographic |
Norway Norwegian Sea Spate |
geographic_facet |
Norway Norwegian Sea Spate |
genre |
Atlantic salmon North East Atlantic Norwegian Sea Salmo salar |
genre_facet |
Atlantic salmon North East Atlantic Norwegian Sea Salmo salar |
op_source |
Frontiers in Microbiology volume 14 ISSN 1664-302X |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3389/fmicb.2023.1236290 |
container_title |
Frontiers in Microbiology |
container_volume |
14 |
_version_ |
1790598135609819136 |