Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance
Methicillin-resistant Staphylococcus aureus (MRSA) is notifiable in Denmark, Finland, Iceland, Norway and Sweden. The prevalence of MRSA in this region has been low for many years, but all five countries experience increasing numbers of new cases. The aim of the study was to describe the molecular e...
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Online Access: | http://dx.doi.org/10.3389/fmicb.2021.668900 https://www.frontiersin.org/articles/10.3389/fmicb.2021.668900/full |
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crfrontiers:10.3389/fmicb.2021.668900 2024-10-06T13:49:57+00:00 Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance Petersen, Andreas Larssen, Kjersti W. Gran, Frode W. Enger, Hege Hæggman, Sara Mäkitalo, Barbro Haraldsson, Gunnsteinn Lindholm, Laura Vuopio, Jaana Henius, Anna Emilie Nielsen, Jens Larsen, Anders R. Svenska Läkaresällskapet 2021 http://dx.doi.org/10.3389/fmicb.2021.668900 https://www.frontiersin.org/articles/10.3389/fmicb.2021.668900/full unknown Frontiers Media SA https://creativecommons.org/licenses/by/4.0/ Frontiers in Microbiology volume 12 ISSN 1664-302X journal-article 2021 crfrontiers https://doi.org/10.3389/fmicb.2021.668900 2024-09-24T04:01:44Z Methicillin-resistant Staphylococcus aureus (MRSA) is notifiable in Denmark, Finland, Iceland, Norway and Sweden. The prevalence of MRSA in this region has been low for many years, but all five countries experience increasing numbers of new cases. The aim of the study was to describe the molecular epidemiology in the Nordic countries 2009-2016. Numbers of new cases of MRSA from 1997 to 2016 were compared, and a database containing information on spa -type and place of residence or acquisition, for all new MRSA isolates from 2009 to 2016 was established. A website was developed to visualize the geographic distribution of the spa -types. The incidence of new MRSA cases increased in all Nordic countries with Denmark having 61.8 new cases per 100,000 inhabitants in 2016 as the highest. The number of new cases 2009 to 2016 was 60,984. spa -typing revealed a high genetic diversity, with a total of 2,344 different spa -types identified. The majority of these spa -types (N = 2,017) were found in 1-10 cases. The most common spa -types t127/CC1, t223/CC22, and t304/CC6:8 increased significantly in all Nordic countries during the study period, except for Iceland, while spa -type t002/CC5 decreased in the same four countries. The trends of other common spa -types were different in each of the Nordic countries. The Nordic countries were shown to share similar trends but also to have country-specific characteristics in their MRSA populations. A continued increasing numbers of MRSA will challenge the surveillance economically. A more selected molecular surveillance will probably have to be employed in the future. Article in Journal/Newspaper Iceland Frontiers (Publisher) Norway Frontiers in Microbiology 12 |
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Frontiers (Publisher) |
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Methicillin-resistant Staphylococcus aureus (MRSA) is notifiable in Denmark, Finland, Iceland, Norway and Sweden. The prevalence of MRSA in this region has been low for many years, but all five countries experience increasing numbers of new cases. The aim of the study was to describe the molecular epidemiology in the Nordic countries 2009-2016. Numbers of new cases of MRSA from 1997 to 2016 were compared, and a database containing information on spa -type and place of residence or acquisition, for all new MRSA isolates from 2009 to 2016 was established. A website was developed to visualize the geographic distribution of the spa -types. The incidence of new MRSA cases increased in all Nordic countries with Denmark having 61.8 new cases per 100,000 inhabitants in 2016 as the highest. The number of new cases 2009 to 2016 was 60,984. spa -typing revealed a high genetic diversity, with a total of 2,344 different spa -types identified. The majority of these spa -types (N = 2,017) were found in 1-10 cases. The most common spa -types t127/CC1, t223/CC22, and t304/CC6:8 increased significantly in all Nordic countries during the study period, except for Iceland, while spa -type t002/CC5 decreased in the same four countries. The trends of other common spa -types were different in each of the Nordic countries. The Nordic countries were shown to share similar trends but also to have country-specific characteristics in their MRSA populations. A continued increasing numbers of MRSA will challenge the surveillance economically. A more selected molecular surveillance will probably have to be employed in the future. |
author2 |
Svenska Läkaresällskapet |
format |
Article in Journal/Newspaper |
author |
Petersen, Andreas Larssen, Kjersti W. Gran, Frode W. Enger, Hege Hæggman, Sara Mäkitalo, Barbro Haraldsson, Gunnsteinn Lindholm, Laura Vuopio, Jaana Henius, Anna Emilie Nielsen, Jens Larsen, Anders R. |
spellingShingle |
Petersen, Andreas Larssen, Kjersti W. Gran, Frode W. Enger, Hege Hæggman, Sara Mäkitalo, Barbro Haraldsson, Gunnsteinn Lindholm, Laura Vuopio, Jaana Henius, Anna Emilie Nielsen, Jens Larsen, Anders R. Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance |
author_facet |
Petersen, Andreas Larssen, Kjersti W. Gran, Frode W. Enger, Hege Hæggman, Sara Mäkitalo, Barbro Haraldsson, Gunnsteinn Lindholm, Laura Vuopio, Jaana Henius, Anna Emilie Nielsen, Jens Larsen, Anders R. |
author_sort |
Petersen, Andreas |
title |
Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance |
title_short |
Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance |
title_full |
Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance |
title_fullStr |
Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance |
title_full_unstemmed |
Increasing Incidences and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus in the Nordic Countries - Results From the Nordic MRSA Surveillance |
title_sort |
increasing incidences and clonal diversity of methicillin-resistant staphylococcus aureus in the nordic countries - results from the nordic mrsa surveillance |
publisher |
Frontiers Media SA |
publishDate |
2021 |
url |
http://dx.doi.org/10.3389/fmicb.2021.668900 https://www.frontiersin.org/articles/10.3389/fmicb.2021.668900/full |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Frontiers in Microbiology volume 12 ISSN 1664-302X |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3389/fmicb.2021.668900 |
container_title |
Frontiers in Microbiology |
container_volume |
12 |
_version_ |
1812178044569255936 |