Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides
The abundance of fish and zooplankton (1 × 10 9 tons to 7 × 10 10 tons) in the mesopelagic zone of the ocean is a source of novel raw materials that provides opportunities for sustainable new product development. The peculiar conditions of light and pressure in this ecological zone and the position...
Published in: | Frontiers in Marine Science |
---|---|
Main Authors: | , , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | unknown |
Published: |
Frontiers Media SA
2021
|
Subjects: | |
Online Access: | http://dx.doi.org/10.3389/fmars.2021.719608 https://www.frontiersin.org/articles/10.3389/fmars.2021.719608/full |
id |
crfrontiers:10.3389/fmars.2021.719608 |
---|---|
record_format |
openpolar |
spelling |
crfrontiers:10.3389/fmars.2021.719608 2024-09-30T14:38:24+00:00 Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides Naik, Azza S. Whitaker, R. D. Albrektsen, S. Solstad, Runar G. Thoresen, Lars Hayes, Maria Horizon 2020 Framework Programme 2021 http://dx.doi.org/10.3389/fmars.2021.719608 https://www.frontiersin.org/articles/10.3389/fmars.2021.719608/full unknown Frontiers Media SA https://creativecommons.org/licenses/by/4.0/ Frontiers in Marine Science volume 8 ISSN 2296-7745 journal-article 2021 crfrontiers https://doi.org/10.3389/fmars.2021.719608 2024-09-17T04:13:45Z The abundance of fish and zooplankton (1 × 10 9 tons to 7 × 10 10 tons) in the mesopelagic zone of the ocean is a source of novel raw materials that provides opportunities for sustainable new product development. The peculiar conditions of light and pressure in this ecological zone and the position of the specific organisms in the marine food chain results in diversity in their bio-composition. Mesopelagic fish are an underutilized resource, rich in proteins and omega-3 oils, and present opportunities to develop novel feed, food and functional food ingredients and products. However, there is also a need to ensure that this resource is not overfished and is processed to optimize the catch in line with sustainability goals. There is therefore a need to establish sustainable bioprocessing technologies to yield value added products from mesopelagic fish species. In the present study, various protein extracts from the mesopelagic fish Maurolicus muelleri (M) and Meganyctiphanes norvegica (Northern Krill) (K) and combinations of proteins from these species (C) were generated using hydrolysis methods. Protein Hydrolysates were generated using four different enzymes including Alcalase, endocut-01, endogenous M/K enzymes and FoodPro PNL. Hydrolysates were characterized and assessed for their ability to inhibit enzymes important in diseases associated with metabolic syndrome. The ability of generated Hydrolysates to inhibit enzymes including Angiotensin-1-converting enzyme (ACE-1; EC. 3.4.15.1) associated with blood pressure regulation, Acetylcholinesterase (AChE; EC 3.1.1.7) associated with maintenance of the nervous system, and Dipeptidyl peptidase IV (DPP-IV; EC 3.4.14.5) linked with development of type-2-diabetes, was determined. In a separate process, the same mesopelagic fish species were transformed into fishmeal, Hydrolysates, fish-silage, and aqueous extracts (AQ) and screened for bioactivities using the same bioassays. The Hydrolysates contained greater than 60% protein (dry weight basis) when analyzed using the ... Article in Journal/Newspaper Meganyctiphanes norvegica Northern krill Frontiers (Publisher) Frontiers in Marine Science 8 |
institution |
Open Polar |
collection |
Frontiers (Publisher) |
op_collection_id |
crfrontiers |
language |
unknown |
description |
The abundance of fish and zooplankton (1 × 10 9 tons to 7 × 10 10 tons) in the mesopelagic zone of the ocean is a source of novel raw materials that provides opportunities for sustainable new product development. The peculiar conditions of light and pressure in this ecological zone and the position of the specific organisms in the marine food chain results in diversity in their bio-composition. Mesopelagic fish are an underutilized resource, rich in proteins and omega-3 oils, and present opportunities to develop novel feed, food and functional food ingredients and products. However, there is also a need to ensure that this resource is not overfished and is processed to optimize the catch in line with sustainability goals. There is therefore a need to establish sustainable bioprocessing technologies to yield value added products from mesopelagic fish species. In the present study, various protein extracts from the mesopelagic fish Maurolicus muelleri (M) and Meganyctiphanes norvegica (Northern Krill) (K) and combinations of proteins from these species (C) were generated using hydrolysis methods. Protein Hydrolysates were generated using four different enzymes including Alcalase, endocut-01, endogenous M/K enzymes and FoodPro PNL. Hydrolysates were characterized and assessed for their ability to inhibit enzymes important in diseases associated with metabolic syndrome. The ability of generated Hydrolysates to inhibit enzymes including Angiotensin-1-converting enzyme (ACE-1; EC. 3.4.15.1) associated with blood pressure regulation, Acetylcholinesterase (AChE; EC 3.1.1.7) associated with maintenance of the nervous system, and Dipeptidyl peptidase IV (DPP-IV; EC 3.4.14.5) linked with development of type-2-diabetes, was determined. In a separate process, the same mesopelagic fish species were transformed into fishmeal, Hydrolysates, fish-silage, and aqueous extracts (AQ) and screened for bioactivities using the same bioassays. The Hydrolysates contained greater than 60% protein (dry weight basis) when analyzed using the ... |
author2 |
Horizon 2020 Framework Programme |
format |
Article in Journal/Newspaper |
author |
Naik, Azza S. Whitaker, R. D. Albrektsen, S. Solstad, Runar G. Thoresen, Lars Hayes, Maria |
spellingShingle |
Naik, Azza S. Whitaker, R. D. Albrektsen, S. Solstad, Runar G. Thoresen, Lars Hayes, Maria Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides |
author_facet |
Naik, Azza S. Whitaker, R. D. Albrektsen, S. Solstad, Runar G. Thoresen, Lars Hayes, Maria |
author_sort |
Naik, Azza S. |
title |
Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides |
title_short |
Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides |
title_full |
Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides |
title_fullStr |
Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides |
title_full_unstemmed |
Mesopelagic Fish Protein Hydrolysates and Extracts: A Source of Novel Anti-Hypertensive and Anti-Diabetic Peptides |
title_sort |
mesopelagic fish protein hydrolysates and extracts: a source of novel anti-hypertensive and anti-diabetic peptides |
publisher |
Frontiers Media SA |
publishDate |
2021 |
url |
http://dx.doi.org/10.3389/fmars.2021.719608 https://www.frontiersin.org/articles/10.3389/fmars.2021.719608/full |
genre |
Meganyctiphanes norvegica Northern krill |
genre_facet |
Meganyctiphanes norvegica Northern krill |
op_source |
Frontiers in Marine Science volume 8 ISSN 2296-7745 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3389/fmars.2021.719608 |
container_title |
Frontiers in Marine Science |
container_volume |
8 |
_version_ |
1811641060510662656 |