Sweepstakes reproductive success via pervasive and recurrent selective sweeps
Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of...
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2023
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Online Access: | http://dx.doi.org/10.7554/elife.80781 https://cdn.elifesciences.org/articles/80781/elife-80781-v1.pdf https://cdn.elifesciences.org/articles/80781/elife-80781-v1.xml https://elifesciences.org/articles/80781 |
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crelifesciences:10.7554/elife.80781 2024-10-13T14:05:56+00:00 Sweepstakes reproductive success via pervasive and recurrent selective sweeps Árnason, Einar Koskela, Jere Halldórsdóttir, Katrín Eldon, Bjarki Rannsóknasjóður. Rannís Deutsche Forschungsgemeinschaft Engineering and Physical Sciences Research Council Deutsche Forschungsgemeinschaft 2023 http://dx.doi.org/10.7554/elife.80781 https://cdn.elifesciences.org/articles/80781/elife-80781-v1.pdf https://cdn.elifesciences.org/articles/80781/elife-80781-v1.xml https://elifesciences.org/articles/80781 en eng eLife Sciences Publications, Ltd http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ eLife volume 12 ISSN 2050-084X journal-article 2023 crelifesciences https://doi.org/10.7554/elife.80781 2024-09-17T04:53:18Z Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of highly fecund populations. The concept of sweepstakes reproductive success, which posits a considerable variance and skew in individual reproductive output, is key to understanding the distribution of individual reproductive success. However, it still needs to be determined whether highly fecund organisms reproduce through sweepstakes and, if they do, the relative roles of neutral and selective sweepstakes. Here, we use coalescent-based statistical analysis of population genomic data to show that selective sweepstakes likely explain recruitment dynamics in the highly fecund Atlantic cod. We show that the Kingman coalescent (modelling no sweepstakes) and the Xi-Beta coalescent (modelling random sweepstakes), including complex demography and background selection, do not provide an adequate fit for the data. The Durrett–Schweinsberg coalescent, in which selective sweepstakes result from recurrent and pervasive selective sweeps of new mutations, offers greater explanatory power. Our results show that models of sweepstakes reproduction and multiple-merger coalescents are relevant and necessary for understanding genetic diversity in highly fecund natural populations. These findings have fundamental implications for understanding the recruitment variation of fish stocks and general evolutionary genomics of high-fecundity organisms. Article in Journal/Newspaper atlantic cod eLife eLife 12 |
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Open Polar |
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eLife |
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crelifesciences |
language |
English |
description |
Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of highly fecund populations. The concept of sweepstakes reproductive success, which posits a considerable variance and skew in individual reproductive output, is key to understanding the distribution of individual reproductive success. However, it still needs to be determined whether highly fecund organisms reproduce through sweepstakes and, if they do, the relative roles of neutral and selective sweepstakes. Here, we use coalescent-based statistical analysis of population genomic data to show that selective sweepstakes likely explain recruitment dynamics in the highly fecund Atlantic cod. We show that the Kingman coalescent (modelling no sweepstakes) and the Xi-Beta coalescent (modelling random sweepstakes), including complex demography and background selection, do not provide an adequate fit for the data. The Durrett–Schweinsberg coalescent, in which selective sweepstakes result from recurrent and pervasive selective sweeps of new mutations, offers greater explanatory power. Our results show that models of sweepstakes reproduction and multiple-merger coalescents are relevant and necessary for understanding genetic diversity in highly fecund natural populations. These findings have fundamental implications for understanding the recruitment variation of fish stocks and general evolutionary genomics of high-fecundity organisms. |
author2 |
Rannsóknasjóður. Rannís Deutsche Forschungsgemeinschaft Engineering and Physical Sciences Research Council Deutsche Forschungsgemeinschaft |
format |
Article in Journal/Newspaper |
author |
Árnason, Einar Koskela, Jere Halldórsdóttir, Katrín Eldon, Bjarki |
spellingShingle |
Árnason, Einar Koskela, Jere Halldórsdóttir, Katrín Eldon, Bjarki Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
author_facet |
Árnason, Einar Koskela, Jere Halldórsdóttir, Katrín Eldon, Bjarki |
author_sort |
Árnason, Einar |
title |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_short |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_full |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_fullStr |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_full_unstemmed |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_sort |
sweepstakes reproductive success via pervasive and recurrent selective sweeps |
publisher |
eLife Sciences Publications, Ltd |
publishDate |
2023 |
url |
http://dx.doi.org/10.7554/elife.80781 https://cdn.elifesciences.org/articles/80781/elife-80781-v1.pdf https://cdn.elifesciences.org/articles/80781/elife-80781-v1.xml https://elifesciences.org/articles/80781 |
genre |
atlantic cod |
genre_facet |
atlantic cod |
op_source |
eLife volume 12 ISSN 2050-084X |
op_rights |
http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.7554/elife.80781 |
container_title |
eLife |
container_volume |
12 |
_version_ |
1812811975330103296 |