Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.

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Format: Other/Unknown Material
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Published: eLife Sciences Publications, Ltd 2018
Subjects:
Carbonic acid
Online Access:http://dx.doi.org/10.7554/elife.39169.002
id crelifesciences:10.7554/elife.39169.002
record_format openpolar
spelling crelifesciences:10.7554/elife.39169.002 2023-07-23T04:18:47+02:00 Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways. (A) The XF measures oxygen consumption rate (OCR) of the cell, which is mostly consumed at complex IV of the electron transport chain (ETC) in the mitochondria, and extracellular acidification rate (ECAR), which is generated from lactic acid produced from pyruvate, the end-product of glycolysis, and carbonic acid produced from CO2 released during the TCA cycle. Assays performed on the XF include: (B) mitochondrial respiration test, (C) extracellular acidification test, (D) glycolytic rate assay, (E) mitochondrial fuel test, (F) fatty acid oxidation assay and (G) real-time ATP rate assay. Oligo, oligomycin; FCCP, cyanide-4-[trifluoromethoxy]phenylhydrazone; AntiA and Rot, antimycin A and rotenone; 2-DG, 2-Deoxyglucose; G-6-P, glucose-6-phosphate; G-3-P, glyceraldehyde-3-phosphate; PEP, phosphoenolpyruvate; α-KG, α-ketoglutarate; OAA, oxaloacetate. 2018-12-07T12:00:20Z http://dx.doi.org/10.7554/elife.39169.002 unknown eLife Sciences Publications, Ltd component 2018 crelifesciences https://doi.org/10.7554/elife.39169.002 2023-07-05T08:45:41Z Other/Unknown Material Carbonic acid eLife (E-Journal - via Crossref)
institution Open Polar
collection eLife (E-Journal - via Crossref)
op_collection_id crelifesciences
language unknown
format Other/Unknown Material
title Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
spellingShingle Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
title_short Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
title_full Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
title_fullStr Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
title_full_unstemmed Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
title_sort figure 1. schematic illustration of cellular metabolism pathways and xf assays used to analyze metabolic pathways.
publisher eLife Sciences Publications, Ltd
publishDate 2018
url http://dx.doi.org/10.7554/elife.39169.002
genre Carbonic acid
genre_facet Carbonic acid
op_doi https://doi.org/10.7554/elife.39169.002
_version_ 1772181398808952832

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