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crelifesciences:10.7554/elife.39169.002
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openpolar
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crelifesciences:10.7554/elife.39169.002 2023-07-23T04:18:47+02:00 Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways. (A) The XF measures oxygen consumption rate (OCR) of the cell, which is mostly consumed at complex IV of the electron transport chain (ETC) in the mitochondria, and extracellular acidification rate (ECAR), which is generated from lactic acid produced from pyruvate, the end-product of glycolysis, and carbonic acid produced from CO2 released during the TCA cycle. Assays performed on the XF include: (B) mitochondrial respiration test, (C) extracellular acidification test, (D) glycolytic rate assay, (E) mitochondrial fuel test, (F) fatty acid oxidation assay and (G) real-time ATP rate assay. Oligo, oligomycin; FCCP, cyanide-4-[trifluoromethoxy]phenylhydrazone; AntiA and Rot, antimycin A and rotenone; 2-DG, 2-Deoxyglucose; G-6-P, glucose-6-phosphate; G-3-P, glyceraldehyde-3-phosphate; PEP, phosphoenolpyruvate; α-KG, α-ketoglutarate; OAA, oxaloacetate. 2018-12-07T12:00:20Z http://dx.doi.org/10.7554/elife.39169.002 unknown eLife Sciences Publications, Ltd component 2018 crelifesciences https://doi.org/10.7554/elife.39169.002 2023-07-05T08:45:41Z Other/Unknown Material Carbonic acid eLife (E-Journal - via Crossref)
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Open Polar
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eLife (E-Journal - via Crossref)
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crelifesciences
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unknown
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format |
Other/Unknown Material
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title |
Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
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spellingShingle |
Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
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title_short |
Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
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title_full |
Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
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title_fullStr |
Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
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title_full_unstemmed |
Figure 1. Schematic illustration of cellular metabolism pathways and XF assays used to analyze metabolic pathways.
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title_sort |
figure 1. schematic illustration of cellular metabolism pathways and xf assays used to analyze metabolic pathways.
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publisher |
eLife Sciences Publications, Ltd
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publishDate |
2018
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url |
http://dx.doi.org/10.7554/elife.39169.002
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genre |
Carbonic acid
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genre_facet |
Carbonic acid
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op_doi |
https://doi.org/10.7554/elife.39169.002
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_version_ |
1772181398808952832
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