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crelifesciences:10.7554/elife.06496.012
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openpolar
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crelifesciences:10.7554/elife.06496.012 2023-07-23T04:21:14+02:00 Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture. (A) a. Regions with H3K9me3 peaks detected by ChIP-seq plotted along the length of the chromosomes in which they reside. Chromosome scale indicated at the bottom of the chromosomes. b. Regions showing less than 1.3 fold decreases in H3K9me3 upon ORCA knockdown plotted along the length of the chromosomes in which they reside. Chromosome scale is indicated at the bottom of the chromosomes. (B) a-c. Representative regions showing significant decrease in the reads in H3K9me3 ChIP on ORCA knockdown. c-FOS, a region which doesn’t show decrease in H3K9me3 is also shown. (C) a-b. H3K9me2 ChIP at regions showing decrease in H3K9me3. (D) Chromatin fractionation in ORCA depleted U2OS cells and G9a and Suv39H1 IB analyses. SRSF1, a splicing factor, was used as loading control. (E) a. G9a ChIP and b. IgG ChIP at regions showing alterations in H3K9me2 and me3. Error bars represent s.d, n=3. 2015-05-25T11:15:30Z http://dx.doi.org/10.7554/elife.06496.012 unknown eLife Sciences Publications, Ltd component 2015 crelifesciences https://doi.org/10.7554/elife.06496.012 2023-07-05T08:34:48Z Other/Unknown Material Orca eLife (E-Journal - via Crossref)
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institution |
Open Polar
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collection |
eLife (E-Journal - via Crossref)
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op_collection_id |
crelifesciences
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language |
unknown
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format |
Other/Unknown Material
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title |
Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture.
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spellingShingle |
Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture.
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title_short |
Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture.
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title_full |
Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture.
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title_fullStr |
Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture.
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title_full_unstemmed |
Figure 5—figure supplement 1. ORCA depletion causes changes in chromatin architecture.
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title_sort |
figure 5—figure supplement 1. orca depletion causes changes in chromatin architecture.
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publisher |
eLife Sciences Publications, Ltd
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publishDate |
2015
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url |
http://dx.doi.org/10.7554/elife.06496.012
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genre |
Orca
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genre_facet |
Orca
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op_doi |
https://doi.org/10.7554/elife.06496.012
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_version_ |
1772186567159316480
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