Carboxylation of hydroxyarens with metal alkyl carbonates
Abstract The objective of this work was to investigate the possibility of using alkali metal salts of ethylcarbonic acid as a carboxylating reagent in phenol (naphthols) carboxylation and developing a new and simple method for the synthesis of hydroxybenzoic and hydroxynaphthoic acids having broad p...
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crdegruyter:10.1515/gps-2014-0098 2023-05-15T15:52:43+02:00 Carboxylation of hydroxyarens with metal alkyl carbonates Suerbaev, Khakim A. Aldabergenov, Mayliby K. Kudaibergenov, Nurbolat Zh. 2015 http://dx.doi.org/10.1515/gps-2014-0098 https://www.degruyter.com/document/doi/10.1515/gps-2014-0098/pdf unknown Walter de Gruyter GmbH Green Processing and Synthesis volume 4, issue 2 ISSN 2191-9550 2191-9542 Health, Toxicology and Mutagenesis Industrial and Manufacturing Engineering Fuel Technology Renewable Energy, Sustainability and the Environment General Chemical Engineering Environmental Chemistry journal-article 2015 crdegruyter https://doi.org/10.1515/gps-2014-0098 2022-04-14T05:01:09Z Abstract The objective of this work was to investigate the possibility of using alkali metal salts of ethylcarbonic acid as a carboxylating reagent in phenol (naphthols) carboxylation and developing a new and simple method for the synthesis of hydroxybenzoic and hydroxynaphthoic acids having broad practical application. It was found that sodium ethyl carbonate and potassium ethyl carbonate can be successfully used as carboxylating agents in carboxylation of phenol and naphthols. For the first time, the effects of the gaseous medium (air, carbon dioxide, argon), pressure, temperature and reaction time on the proceedings of the carboxylation reactions were examined. Simple and convenient procedures for the syntheses of o- and p-hydroxybenzoic, p-aminosalicylic, 1-hydroxy-2-naphthoic, 1-hydroxy-4-naphthoic and 2-hydroxy-3-naphthoic acids were developed. New efficient technologies for preparation of drugs salicylic acid (antiseptic activity), p-aminosalicylic acid (antituberculous activity) and p-hydroxybenzoic acid (bactericide activity) based on carboxylation reactions of phenol and m-aminophenol with sodium and potassium salts of ethyl carbonic acid were worked out. Article in Journal/Newspaper Carbonic acid De Gruyter (via Crossref) Green Processing and Synthesis 4 2 |
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De Gruyter (via Crossref) |
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Health, Toxicology and Mutagenesis Industrial and Manufacturing Engineering Fuel Technology Renewable Energy, Sustainability and the Environment General Chemical Engineering Environmental Chemistry |
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Health, Toxicology and Mutagenesis Industrial and Manufacturing Engineering Fuel Technology Renewable Energy, Sustainability and the Environment General Chemical Engineering Environmental Chemistry Suerbaev, Khakim A. Aldabergenov, Mayliby K. Kudaibergenov, Nurbolat Zh. Carboxylation of hydroxyarens with metal alkyl carbonates |
topic_facet |
Health, Toxicology and Mutagenesis Industrial and Manufacturing Engineering Fuel Technology Renewable Energy, Sustainability and the Environment General Chemical Engineering Environmental Chemistry |
description |
Abstract The objective of this work was to investigate the possibility of using alkali metal salts of ethylcarbonic acid as a carboxylating reagent in phenol (naphthols) carboxylation and developing a new and simple method for the synthesis of hydroxybenzoic and hydroxynaphthoic acids having broad practical application. It was found that sodium ethyl carbonate and potassium ethyl carbonate can be successfully used as carboxylating agents in carboxylation of phenol and naphthols. For the first time, the effects of the gaseous medium (air, carbon dioxide, argon), pressure, temperature and reaction time on the proceedings of the carboxylation reactions were examined. Simple and convenient procedures for the syntheses of o- and p-hydroxybenzoic, p-aminosalicylic, 1-hydroxy-2-naphthoic, 1-hydroxy-4-naphthoic and 2-hydroxy-3-naphthoic acids were developed. New efficient technologies for preparation of drugs salicylic acid (antiseptic activity), p-aminosalicylic acid (antituberculous activity) and p-hydroxybenzoic acid (bactericide activity) based on carboxylation reactions of phenol and m-aminophenol with sodium and potassium salts of ethyl carbonic acid were worked out. |
format |
Article in Journal/Newspaper |
author |
Suerbaev, Khakim A. Aldabergenov, Mayliby K. Kudaibergenov, Nurbolat Zh. |
author_facet |
Suerbaev, Khakim A. Aldabergenov, Mayliby K. Kudaibergenov, Nurbolat Zh. |
author_sort |
Suerbaev, Khakim A. |
title |
Carboxylation of hydroxyarens with metal alkyl carbonates |
title_short |
Carboxylation of hydroxyarens with metal alkyl carbonates |
title_full |
Carboxylation of hydroxyarens with metal alkyl carbonates |
title_fullStr |
Carboxylation of hydroxyarens with metal alkyl carbonates |
title_full_unstemmed |
Carboxylation of hydroxyarens with metal alkyl carbonates |
title_sort |
carboxylation of hydroxyarens with metal alkyl carbonates |
publisher |
Walter de Gruyter GmbH |
publishDate |
2015 |
url |
http://dx.doi.org/10.1515/gps-2014-0098 https://www.degruyter.com/document/doi/10.1515/gps-2014-0098/pdf |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_source |
Green Processing and Synthesis volume 4, issue 2 ISSN 2191-9550 2191-9542 |
op_doi |
https://doi.org/10.1515/gps-2014-0098 |
container_title |
Green Processing and Synthesis |
container_volume |
4 |
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2 |
_version_ |
1766387823158493184 |