A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell
Numerous large perisinusoidal cells containing prominent cytoplasmic lipid droplets were observed in the livers of adult and subadult polar bears (Ursus maritimus). The cells were identified as Ito cells by histological, histochemical, and ultrastructural criteria. The ratio of Ito cell to hepatocyt...
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Language: | English |
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Canadian Science Publishing
1988
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Online Access: | http://dx.doi.org/10.1139/z88-068 http://www.nrcresearchpress.com/doi/pdf/10.1139/z88-068 |
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crcansciencepubl:10.1139/z88-068 2023-12-17T10:49:02+01:00 A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell Leighton, F. A. Cattet, M. Norstrom, R. Trudeau, S. 1988 http://dx.doi.org/10.1139/z88-068 http://www.nrcresearchpress.com/doi/pdf/10.1139/z88-068 en eng Canadian Science Publishing http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining Canadian Journal of Zoology volume 66, issue 2, page 480-482 ISSN 0008-4301 1480-3283 Animal Science and Zoology Ecology, Evolution, Behavior and Systematics journal-article 1988 crcansciencepubl https://doi.org/10.1139/z88-068 2023-11-19T13:39:23Z Numerous large perisinusoidal cells containing prominent cytoplasmic lipid droplets were observed in the livers of adult and subadult polar bears (Ursus maritimus). The cells were identified as Ito cells by histological, histochemical, and ultrastructural criteria. The ratio of Ito cell to hepatocyte numbers in three bears was 1:5.6, much higher than that reported in humans. Total liver retinol and retinol palmitate in three livers correlated well with mean Ito cell area (r = 0.98). We postulate that the large number and size of Ito cells in polar bear livers is an adaptation to high dietary levels of vitamin A. Article in Journal/Newspaper polar bear Ursus maritimus Canadian Science Publishing (via Crossref) Canadian Journal of Zoology 66 2 480 482 |
institution |
Open Polar |
collection |
Canadian Science Publishing (via Crossref) |
op_collection_id |
crcansciencepubl |
language |
English |
topic |
Animal Science and Zoology Ecology, Evolution, Behavior and Systematics |
spellingShingle |
Animal Science and Zoology Ecology, Evolution, Behavior and Systematics Leighton, F. A. Cattet, M. Norstrom, R. Trudeau, S. A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell |
topic_facet |
Animal Science and Zoology Ecology, Evolution, Behavior and Systematics |
description |
Numerous large perisinusoidal cells containing prominent cytoplasmic lipid droplets were observed in the livers of adult and subadult polar bears (Ursus maritimus). The cells were identified as Ito cells by histological, histochemical, and ultrastructural criteria. The ratio of Ito cell to hepatocyte numbers in three bears was 1:5.6, much higher than that reported in humans. Total liver retinol and retinol palmitate in three livers correlated well with mean Ito cell area (r = 0.98). We postulate that the large number and size of Ito cells in polar bear livers is an adaptation to high dietary levels of vitamin A. |
format |
Article in Journal/Newspaper |
author |
Leighton, F. A. Cattet, M. Norstrom, R. Trudeau, S. |
author_facet |
Leighton, F. A. Cattet, M. Norstrom, R. Trudeau, S. |
author_sort |
Leighton, F. A. |
title |
A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell |
title_short |
A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell |
title_full |
A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell |
title_fullStr |
A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell |
title_full_unstemmed |
A cellular basis for high levels of vitamin A in livers of polar bears ( Ursus maritimus ): the Ito cell |
title_sort |
cellular basis for high levels of vitamin a in livers of polar bears ( ursus maritimus ): the ito cell |
publisher |
Canadian Science Publishing |
publishDate |
1988 |
url |
http://dx.doi.org/10.1139/z88-068 http://www.nrcresearchpress.com/doi/pdf/10.1139/z88-068 |
genre |
polar bear Ursus maritimus |
genre_facet |
polar bear Ursus maritimus |
op_source |
Canadian Journal of Zoology volume 66, issue 2, page 480-482 ISSN 0008-4301 1480-3283 |
op_rights |
http://www.nrcresearchpress.com/page/about/CorporateTextAndDataMining |
op_doi |
https://doi.org/10.1139/z88-068 |
container_title |
Canadian Journal of Zoology |
container_volume |
66 |
container_issue |
2 |
container_start_page |
480 |
op_container_end_page |
482 |
_version_ |
1785573384783921152 |